BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 23331088)

  • 1. Metabolism of R- and S-warfarin by CYP2C19 into four hydroxywarfarins.
    Kim SY; Kang JY; Hartman JH; Park SH; Jones DR; Yun CH; Boysen G; Miller GP
    Drug Metab Lett; 2012 Sep; 6(3):157-64. PubMed ID: 23331088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.
    Jones DR; Kim SY; Guderyon M; Yun CH; Moran JH; Miller GP
    Chem Res Toxicol; 2010 May; 23(5):939-45. PubMed ID: 20429590
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regioselectivity significantly impacts microsomal glucuronidation efficiency of R/S-6, 7-, and 8-hydroxywarfarin.
    Kim SY; Jones DR; Kang JY; Yun CH; Miller GP
    Xenobiotica; 2019 Apr; 49(4):397-403. PubMed ID: 29543105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.
    Zielinska A; Lichti CF; Bratton S; Mitchell NC; Gallus-Zawada A; Le VH; Finel M; Miller GP; Radominska-Pandya A; Moran JH
    J Pharmacol Exp Ther; 2008 Jan; 324(1):139-48. PubMed ID: 17921187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes.
    Takahashi H; Kashima T; Nomizo Y; Muramoto N; Shimizu T; Nasu K; Kubota T; Kimura S; Echizen H
    Clin Pharmacol Ther; 1998 May; 63(5):519-28. PubMed ID: 9630825
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
    Wienkers LC; Wurden CJ; Storch E; Kunze KL; Rettie AE; Trager WF
    Drug Metab Dispos; 1996 May; 24(5):610-4. PubMed ID: 8723744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.
    Jones DR; Kim SY; Boysen G; Yun CH; Miller GP
    Drug Metab Lett; 2010 Dec; 4(4):213-9. PubMed ID: 20615193
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques.
    Uno Y; Matsushita A; Shukuya M; Matsumoto Y; Murayama N; Yamazaki H
    Biochem Pharmacol; 2014 Sep; 91(2):242-8. PubMed ID: 25036290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Warfarin analog inhibition of human CYP2C9-catalyzed S-warfarin 7-hydroxylation.
    Zhang ZY; Kerr J; Wexler RS; Li HY; Robinson AJ; Harlow PP; Kaminsky LS
    Thromb Res; 1997 Nov; 88(4):389-98. PubMed ID: 9526963
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9.
    He M; Korzekwa KR; Jones JP; Rettie AE; Trager WF
    Arch Biochem Biophys; 1999 Dec; 372(1):16-28. PubMed ID: 10562412
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
    Inoue T; Nitta K; Sugihara K; Horie T; Kitamura S; Ohta S
    Drug Metab Dispos; 2008 Dec; 36(12):2429-33. PubMed ID: 18784266
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases.
    Bratton SM; Mosher CM; Khallouki F; Finel M; Court MH; Moran JH; Radominska-Pandya A
    J Pharmacol Exp Ther; 2012 Jan; 340(1):46-55. PubMed ID: 21972237
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.
    Pugh CP; Pouncey DL; Hartman JH; Nshimiyimana R; Desrochers LP; Goodwin TE; Boysen G; Miller GP
    Arch Biochem Biophys; 2014 Dec; 564():244-53. PubMed ID: 25447818
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions.
    Rettie AE; Korzekwa KR; Kunze KL; Lawrence RF; Eddy AC; Aoyama T; Gelboin HV; Gonzalez FJ; Trager WF
    Chem Res Toxicol; 1992; 5(1):54-9. PubMed ID: 1581537
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM; Wester MR; Aramsombatdee E; Raucy JL
    Arch Biochem Biophys; 1998 May; 353(1):16-28. PubMed ID: 9578596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of ethanol on S-warfarin and diclofenac metabolism by recombinant human CYP2C9.1.
    Tatsumi A; Ikegami Y; Morii R; Sugiyama M; Kadobayashi M; Iwakawa S
    Biol Pharm Bull; 2009 Mar; 32(3):517-9. PubMed ID: 19252308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies.
    Kunze KL; Wienkers LC; Thummel KE; Trager WF
    Drug Metab Dispos; 1996 Apr; 24(4):414-21. PubMed ID: 8801056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of glimepiride and glibenclamide on S-warfarin 7-hydroxylation by human liver microsomes, recombinant human CYP2C9.1 and CYP2C9.3.
    Iwakawa S; Miyashita K; Hashimoto Y; Kuroda T
    Biol Pharm Bull; 2006 Sep; 29(9):1983-5. PubMed ID: 16946524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel multi-mode ultra performance liquid chromatography-tandem mass spectrometry assay for profiling enantiomeric hydroxywarfarins and warfarin in human plasma.
    Jones DR; Boysen G; Miller GP
    J Chromatogr B Analyt Technol Biomed Life Sci; 2011 May; 879(15-16):1056-62. PubMed ID: 21470921
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H; Shimada T
    Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.