BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 23331901)

  • 1. The decrease in farnesoid X receptor, pregnane X receptor and constitutive androstane receptor in the liver after intestinal ischemia-reperfusion.
    Ogura J; Terada Y; Tsujimoto T; Koizumi T; Kuwayama K; Maruyama H; Fujikawa A; Takaya A; Kobayashi M; Itagaki S; Takahashi N; Hirano T; Yamaguchi H; Iseki K
    J Pharm Pharm Sci; 2012; 15(5):616-31. PubMed ID: 23331901
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
    Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
    J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
    Guo GL; Lambert G; Negishi M; Ward JM; Brewer HB; Kliewer SA; Gonzalez FJ; Sinal CJ
    J Biol Chem; 2003 Nov; 278(46):45062-71. PubMed ID: 12923173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
    Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
    Luisier R; Lempiäinen H; Scherbichler N; Braeuning A; Geissler M; Dubost V; Müller A; Scheer N; Chibout SD; Hara H; Picard F; Theil D; Couttet P; Vitobello A; Grenet O; Grasl-Kraupp B; Ellinger-Ziegelbauer H; Thomson JP; Meehan RR; Elcombe CR; Henderson CJ; Wolf CR; Schwarz M; Moulin P; Terranova R; Moggs JG
    Toxicol Sci; 2014 Jun; 139(2):501-11. PubMed ID: 24690595
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
    Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
    Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes.
    Howe K; Sanat F; Thumser AE; Coleman T; Plant N
    Xenobiotica; 2011 Jul; 41(7):519-29. PubMed ID: 21476904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels.
    Chang TK; Bandiera SM; Chen J
    Drug Metab Dispos; 2003 Jan; 31(1):7-10. PubMed ID: 12485946
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor.
    Liu MJ; Takahashi Y; Wada T; He J; Gao J; Tian Y; Li S; Xie W
    Mol Pharmacol; 2009 Sep; 76(3):604-11. PubMed ID: 19542321
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity.
    Lim YP; Cheng CH; Chen WC; Chang SY; Hung DZ; Chen JJ; Wan L; Ma WC; Lin YH; Chen CY; Yokoi T; Nakajima M; Chen CJ
    Arch Toxicol; 2015 Jan; 89(1):57-72. PubMed ID: 25069801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis.
    Gabbia D; Pozza AD; Albertoni L; Lazzari R; Zigiotto G; Carrara M; Baldo V; Baldovin T; Floreani A; Martin S
    World J Gastroenterol; 2017 Nov; 23(42):7519-7530. PubMed ID: 29204052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Repression of farnesoid X receptor during the acute phase response.
    Kim MS; Shigenaga J; Moser A; Feingold K; Grunfeld C
    J Biol Chem; 2003 Mar; 278(11):8988-95. PubMed ID: 12519762
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK; Hoque MT; Jenabian MA; Routy JP; Bendayan R
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interplay of pregnane X receptor with other nuclear receptors on gene regulation.
    Lim YP; Huang JD
    Drug Metab Pharmacokinet; 2008; 23(1):14-21. PubMed ID: 18305371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear receptors and nonalcoholic fatty liver disease.
    Cave MC; Clair HB; Hardesty JE; Falkner KC; Feng W; Clark BJ; Sidey J; Shi H; Aqel BA; McClain CJ; Prough RA
    Biochim Biophys Acta; 2016 Sep; 1859(9):1083-1099. PubMed ID: 26962021
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
    Cui JY; Klaassen CD
    Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders.
    Fiorucci S; Zampella A; Distrutti E
    Curr Top Med Chem; 2012; 12(6):605-24. PubMed ID: 22242859
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
    Hu Q; Yao N; Wu J; Liu M; Liu F; Zhang H; Xiong Y; Xia C
    Biochem Pharmacol; 2019 Jan; 159():32-39. PubMed ID: 30414935
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression.
    Zhang S; Pan X; Jeong H
    Drug Metab Dispos; 2015 May; 43(5):743-8. PubMed ID: 25725071
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.