BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 23333829)

  • 1. Evaluation of intestinal absorption of amtolmetin guacyl in rats: breast cancer resistant protein as a primary barrier of oral bioavailability.
    Rong Z; Xu Y; Zhang C; Xiang D; Li X; Liu D
    Life Sci; 2013 Feb; 92(3):245-51. PubMed ID: 23333829
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of P-glycoprotein in intestinal transport versus the BBB transport of tetraphenylphosphonium.
    Swed A; Eyal S; Madar I; Zohar-Kontante H; Weiss L; Hoffman A
    Mol Pharm; 2009; 6(6):1883-90. PubMed ID: 19722701
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.
    Ye L; Yang X; Yang Z; Gao S; Yin T; Liu W; Wang F; Hu M; Liu Z
    Toxicol Lett; 2013 Feb; 216(2-3):86-99. PubMed ID: 23200901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
    Dahan A; Amidon GL
    Am J Physiol Gastrointest Liver Physiol; 2009 Aug; 297(2):G371-7. PubMed ID: 19541926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients.
    Yamagata T; Kusuhara H; Morishita M; Takayama K; Benameur H; Sugiyama Y
    Drug Metab Dispos; 2007 Jul; 35(7):1142-8. PubMed ID: 17446265
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo assessment of the impact of efflux transporter on oral drug absorption using portal vein-cannulated rats.
    Matsuda Y; Konno Y; Hashimoto T; Nagai M; Taguchi T; Satsukawa M; Yamashita S
    Drug Metab Dispos; 2013 Aug; 41(8):1514-21. PubMed ID: 23686319
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2).
    Kondo C; Onuki R; Kusuhara H; Suzuki H; Suzuki M; Okudaira N; Kojima M; Ishiwata K; Jonker JW; Sugiyama Y
    Pharm Res; 2005 Apr; 22(4):613-8. PubMed ID: 15846469
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra.
    Cao J; Chen X; Liang J; Yu XQ; Xu AL; Chan E; Wei D; Huang M; Wen JY; Yu XY; Li XT; Sheu FS; Zhou SF
    Drug Metab Dispos; 2007 Apr; 35(4):539-53. PubMed ID: 17220245
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Assessment and modulation of forsythiaside absorption with MDCKII cells and validation with in situ intestinal experiment.
    Li YX; Zhang RQ; Peng C
    Eur J Drug Metab Pharmacokinet; 2012 Sep; 37(3):179-86. PubMed ID: 22430364
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil.
    Choi MK; Song IS
    J Pharm Pharmacol; 2012 Aug; 64(8):1074-83. PubMed ID: 22775210
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mrp2-related efflux of scutellarin in the intestinal absorption in rats.
    Cao F; Zhang H; Guo J; Ping Q
    Pharmazie; 2008 Jan; 63(1):75-80. PubMed ID: 18271309
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of intestinal efflux transporters in the intestinal absorption of methotrexate in rats.
    Yokooji T; Murakami T; Yumoto R; Nagai J; Takano M
    J Pharm Pharmacol; 2007 Sep; 59(9):1263-70. PubMed ID: 17883898
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.
    Li Y; Song W; Ou X; Luo G; Xie Y; Sun R; Wang Y; Qi X; Hu M; Liu Z; Zhu L
    Drug Metab Dispos; 2019 Mar; 47(3):203-214. PubMed ID: 30602435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein.
    Allen JD; Van Dort SC; Buitelaar M; van Tellingen O; Schinkel AH
    Cancer Res; 2003 Mar; 63(6):1339-44. PubMed ID: 12649196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib.
    Chen Y; Agarwal S; Shaik NM; Chen C; Yang Z; Elmquist WF
    J Pharmacol Exp Ther; 2009 Sep; 330(3):956-63. PubMed ID: 19491323
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of efflux transporters involved in distribution and disposition of apixaban.
    Zhang D; He K; Herbst JJ; Kolb J; Shou W; Wang L; Balimane PV; Han YH; Gan J; Frost CE; Humphreys WG
    Drug Metab Dispos; 2013 Apr; 41(4):827-35. PubMed ID: 23382458
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
    Dahan A; Sabit H; Amidon GL
    Drug Metab Dispos; 2009 Oct; 37(10):2028-36. PubMed ID: 19589874
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new intestinal cell culture model to discriminate the relative contribution of P-gp and BCRP on transport of substrates such as imatinib.
    Graber-Maier A; Gutmann H; Drewe J
    Mol Pharm; 2010 Oct; 7(5):1618-28. PubMed ID: 20701289
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan.
    Jonker JW; Smit JW; Brinkhuis RF; Maliepaard M; Beijnen JH; Schellens JH; Schinkel AH
    J Natl Cancer Inst; 2000 Oct; 92(20):1651-6. PubMed ID: 11036110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Breast cancer resistance protein (ABCG2) determines distribution of genistein phase II metabolites: reevaluation of the roles of ABCG2 in the disposition of genistein.
    Yang Z; Zhu W; Gao S; Yin T; Jiang W; Hu M
    Drug Metab Dispos; 2012 Oct; 40(10):1883-93. PubMed ID: 22736306
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.