BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

101 related articles for article (PubMed ID: 23335077)

  • 1. Expression and clinical relevance of MET and ALK in Ewing sarcomas.
    Fleuren ED; Roeffen MH; Leenders WP; Flucke UE; Vlenterie M; Schreuder HW; Boerman OC; van der Graaf WT; Versleijen-Jonkers YM
    Int J Cancer; 2013 Jul; 133(2):427-36. PubMed ID: 23335077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphoproteomic Profiling Reveals ALK and MET as Novel Actionable Targets across Synovial Sarcoma Subtypes.
    Fleuren EDG; Vlenterie M; van der Graaf WTA; Hillebrandt-Roeffen MHS; Blackburn J; Ma X; Chan H; Magias MC; van Erp A; van Houdt L; Cebeci SAS; van de Ven A; Flucke UE; Heyer EE; Thomas DM; Lord CJ; Marini KD; Vaghjiani V; Mercer TR; Cain JE; Wu J; Versleijen-Jonkers YMH; Daly RJ
    Cancer Res; 2017 Aug; 77(16):4279-4292. PubMed ID: 28634201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
    Yamada T; Takeuchi S; Nakade J; Kita K; Nakagawa T; Nanjo S; Nakamura T; Matsumoto K; Soda M; Mano H; Uenaka T; Yano S
    Clin Cancer Res; 2012 Jul; 18(13):3592-602. PubMed ID: 22553343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma.
    Fleuren ED; Hillebrandt-Roeffen MH; Flucke UE; Te Loo DM; Boerman OC; van der Graaf WT; Versleijen-Jonkers YM
    Oncotarget; 2014 Dec; 5(24):12753-68. PubMed ID: 25528764
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crizotinib, a small-molecule dual inhibitor of the c-Met and ALK receptor tyrosine kinases.
    Rodig SJ; Shapiro GI
    Curr Opin Investig Drugs; 2010 Dec; 11(12):1477-90. PubMed ID: 21154129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anaplastic lymphoma kinase protein expression, genetic abnormalities, and phosphorylation in soft tissue tumors: Phosphorylation is associated with recurrent metastasis.
    Ishibashi Y; Miyoshi H; Hiraoka K; Arakawa F; Haraguchi T; Nakashima S; Hashiguchi T; Shoda T; Hamada T; Okawa T; Higuchi F; Shiba N; Nagata K; Ohshima K
    Oncol Rep; 2015 Apr; 33(4):1667-74. PubMed ID: 25683346
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activated MET acts as a salvage signal after treatment with alectinib, a selective ALK inhibitor, in ALK-positive non-small cell lung cancer.
    Kogita A; Togashi Y; Hayashi H; Banno E; Terashima M; De Velasco MA; Sakai K; Fujita Y; Tomida S; Takeyama Y; Okuno K; Nakagawa K; Nishio K
    Int J Oncol; 2015 Mar; 46(3):1025-30. PubMed ID: 25502629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition.
    Liu CN; Mathialagan N; Lappin P; Fortner J; Somps C; Seitis G; Johnson TR; Hu W; Matsumoto D
    Toxicol Sci; 2015 Jan; 143(1):116-25. PubMed ID: 25326243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The preclinical profile of crizotinib for the treatment of non-small-cell lung cancer and other neoplastic disorders.
    Roskoski R
    Expert Opin Drug Discov; 2013 Sep; 8(9):1165-79. PubMed ID: 23805942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of MET genomic amplification, protein expression and alternative splice isoforms in neuroblastomas.
    Yan B; Lim M; Zhou L; Kuick CH; Leong MY; Yong KJ; Aung L; Salto-Tellez M; Chang KT
    J Clin Pathol; 2013 Nov; 66(11):985-91. PubMed ID: 23801497
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Simultaneous targeting of insulin-like growth factor-1 receptor and anaplastic lymphoma kinase in embryonal and alveolar rhabdomyosarcoma: a rational choice.
    van Gaal JC; Roeffen MH; Flucke UE; van der Laak JA; van der Heijden G; de Bont ES; Suurmeijer AJ; Versleijen-Jonkers YM; van der Graaf WT
    Eur J Cancer; 2013 Nov; 49(16):3462-70. PubMed ID: 23867124
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crizotinib-resistant NPM-ALK mutants confer differential sensitivity to unrelated Alk inhibitors.
    Ceccon M; Mologni L; Bisson W; Scapozza L; Gambacorti-Passerini C
    Mol Cancer Res; 2013 Feb; 11(2):122-32. PubMed ID: 23239810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anaplastic lymphoma kinase aberrations in rhabdomyosarcoma: clinical and prognostic implications.
    van Gaal JC; Flucke UE; Roeffen MH; de Bont ES; Sleijfer S; Mavinkurve-Groothuis AM; Suurmeijer AJ; van der Graaf WT; Versleijen-Jonkers YM
    J Clin Oncol; 2012 Jan; 30(3):308-15. PubMed ID: 22184391
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Major partial response to crizotinib, a dual MET/ALK inhibitor, in a squamous cell lung (SCC) carcinoma patient with de novo c-MET amplification in the absence of ALK rearrangement.
    Schwab R; Petak I; Kollar M; Pinter F; Varkondi E; Kohanka A; Barti-Juhasz H; Schönleber J; Brauswetter D; Kopper L; Urban L
    Lung Cancer; 2014 Jan; 83(1):109-11. PubMed ID: 24192513
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High MET receptor expression but not gene amplification in ALK 2p23 rearrangement positive non-small-cell lung cancer.
    Feng Y; Minca EC; Lanigan C; Liu A; Zhang W; Yin L; Pennell NA; Farver C; Tubbs R; Ma PC
    J Thorac Oncol; 2014 May; 9(5):646-53. PubMed ID: 24722154
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crizotinib inhibits migration and expression of ID1 in MET-positive lung cancer cells: implications for MET targeting in oncology.
    Stutz E; Gautschi O; Fey MF; Gugger M; Tschan MP; Rothschild SI
    Future Oncol; 2014 Feb; 10(2):211-7. PubMed ID: 24490607
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetic/pharmacodynamic modeling of crizotinib for anaplastic lymphoma kinase inhibition and antitumor efficacy in human tumor xenograft mouse models.
    Yamazaki S; Vicini P; Shen Z; Zou HY; Lee J; Li Q; Christensen JG; Smith BJ; Shetty B
    J Pharmacol Exp Ther; 2012 Mar; 340(3):549-57. PubMed ID: 22129595
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lung cancers with concomitant EGFR mutations and ALK rearrangements: diverse responses to EGFR-TKI and crizotinib in relation to diverse receptors phosphorylation.
    Yang JJ; Zhang XC; Su J; Xu CR; Zhou Q; Tian HX; Xie Z; Chen HJ; Huang YS; Jiang BY; Wang Z; Wang BC; Yang XN; Zhong WZ; Nie Q; Liao RQ; Mok TS; Wu YL
    Clin Cancer Res; 2014 Mar; 20(5):1383-92. PubMed ID: 24443522
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation-Independent Activation of the Anaplastic Lymphoma Kinase in Neuroblastoma.
    Regairaz M; Munier F; Sartelet H; Castaing M; Marty V; Renauleaud C; Doux C; Delbé J; Courty J; Fabre M; Ohta S; Vielh P; Michiels S; Valteau-Couanet D; Vassal G
    Am J Pathol; 2016 Feb; 186(2):435-45. PubMed ID: 26687816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anaplastic lymphoma kinase gene expression in small round cell tumors of childhood--a comparative ımmunohistochemical study.
    Karakuş E; Emir S; Kaçar A; Karakuş R; Demir HA; Özyörük D
    Ann Diagn Pathol; 2015 Aug; 19(4):239-42. PubMed ID: 26005112
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.