201 related articles for article (PubMed ID: 23340136)
1. Differential selectivity of JAK2 inhibitors in enzymatic and cellular settings.
Yu V; Pistillo J; Archibeque I; Han Lee J; Sun BC; Schenkel LB; Geuns-Meyer S; Liu L; Emkey R
Exp Hematol; 2013 May; 41(5):491-500. PubMed ID: 23340136
[TBL] [Abstract][Full Text] [Related]
2. Discovery of potent and selective pyrazolopyrimidine janus kinase 2 inhibitors.
Hanan EJ; van Abbema A; Barrett K; Blair WS; Blaney J; Chang C; Eigenbrot C; Flynn S; Gibbons P; Hurley CA; Kenny JR; Kulagowski J; Lee L; Magnuson SR; Morris C; Murray J; Pastor RM; Rawson T; Siu M; Ultsch M; Zhou A; Sampath D; Lyssikatos JP
J Med Chem; 2012 Nov; 55(22):10090-107. PubMed ID: 23061660
[TBL] [Abstract][Full Text] [Related]
3. CYT387, a selective JAK1/JAK2 inhibitor: in vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients.
Pardanani A; Lasho T; Smith G; Burns CJ; Fantino E; Tefferi A
Leukemia; 2009 Aug; 23(8):1441-5. PubMed ID: 19295546
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
Dymock BW; See CS
Expert Opin Ther Pat; 2013 Apr; 23(4):449-501. PubMed ID: 23367873
[TBL] [Abstract][Full Text] [Related]
5. Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitors.
Schenkel LB; Huang X; Cheng A; Deak HL; Doherty E; Emkey R; Gu Y; Gunaydin H; Kim JL; Lee J; Loberg R; Olivieri P; Pistillo J; Tang J; Wan Q; Wang HL; Wang SW; Wells MC; Wu B; Yu V; Liu L; Geuns-Meyer S
J Med Chem; 2011 Dec; 54(24):8440-50. PubMed ID: 22087750
[TBL] [Abstract][Full Text] [Related]
6. Comparison of two homogeneous cell-based kinase assays for JAK2 V617F: SureFire pSTAT5 and GeneBLAzer fluorescence resonance energy transfer assays.
Qian J; Mason JL; Holskin BP; Murray KA; Meyer SL; Ator MA; Angeles TS
Assay Drug Dev Technol; 2012 Apr; 10(2):212-7. PubMed ID: 22132729
[TBL] [Abstract][Full Text] [Related]
7. A receptor-independent, cell-based JAK activation assay for screening for JAK3-specific inhibitors.
Oh K; Joo KM; Jung YS; Lee J; Kang H; Lee HY; Lee DS
J Immunol Methods; 2010 Mar; 354(1-2):45-52. PubMed ID: 20138049
[TBL] [Abstract][Full Text] [Related]
8. Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells.
Lacronique V; Boureux A; Monni R; Dumon S; Mauchauffé M; Mayeux P; Gouilleux F; Berger R; Gisselbrecht S; Ghysdael J; Bernard OA
Blood; 2000 Mar; 95(6):2076-83. PubMed ID: 10706877
[TBL] [Abstract][Full Text] [Related]
9. 9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.
Zimmermann K; Sang X; Mastalerz HA; Johnson WL; Zhang G; Liu Q; Batt D; Lombardo LJ; Vyas D; Trainor GL; Tokarski JS; Lorenzi MV; You D; Gottardis MM; Lippy J; Khan J; Sack JS; Purandare AV
Bioorg Med Chem Lett; 2015 Jul; 25(14):2809-12. PubMed ID: 25987372
[TBL] [Abstract][Full Text] [Related]
10. Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling.
Ho JM; Beattie BK; Squire JA; Frank DA; Barber DL
Blood; 1999 Jun; 93(12):4354-64. PubMed ID: 10361134
[TBL] [Abstract][Full Text] [Related]
11. The TEL-Jak2 oncoprotein induces Socs1 expression and altered cytokine response in Ba/F3 cells.
Monni R; Santos SC; Mauchauffe M; Berger R; Ghysdael J; Gouilleux F; Gisselbrecht S; Bernard O; Penard-Lacronique V
Oncogene; 2001 Feb; 20(7):849-58. PubMed ID: 11314018
[TBL] [Abstract][Full Text] [Related]
12. Homoharringtonine affects the JAK2-STAT5 signal pathway through alteration of protein tyrosine kinase phosphorylation in acute myeloid leukemia cells.
Tong H; Ren Y; Zhang F; Jin J
Eur J Haematol; 2008 Oct; 81(4):259-66. PubMed ID: 18616510
[TBL] [Abstract][Full Text] [Related]
13. Discovery of novel Jak2-Stat pathway inhibitors with extended residence time on target.
Guan H; Lamb ML; Peng B; Huang S; Degrace N; Read J; Hussain S; Wu J; Rivard C; Alimzhanov M; Bebernitz G; Bell K; Ye M; Zinda M; Ioannidis S
Bioorg Med Chem Lett; 2013 May; 23(10):3105-10. PubMed ID: 23562594
[TBL] [Abstract][Full Text] [Related]
14. ATP-mediated kinome selectivity: the missing link in understanding the contribution of individual JAK Kinase isoforms to cellular signaling.
Thorarensen A; Banker ME; Fensome A; Telliez JB; Juba B; Vincent F; Czerwinski RM; Casimiro-Garcia A
ACS Chem Biol; 2014 Jul; 9(7):1552-8. PubMed ID: 24814050
[TBL] [Abstract][Full Text] [Related]
15. JAK kinases overexpression promotes in vitro cell transformation.
Knoops L; Hornakova T; Royer Y; Constantinescu SN; Renauld JC
Oncogene; 2008 Mar; 27(11):1511-9. PubMed ID: 17873904
[TBL] [Abstract][Full Text] [Related]
16. TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations.
Pardanani A; Hood J; Lasho T; Levine RL; Martin MB; Noronha G; Finke C; Mak CC; Mesa R; Zhu H; Soll R; Gilliland DG; Tefferi A
Leukemia; 2007 Aug; 21(8):1658-68. PubMed ID: 17541402
[TBL] [Abstract][Full Text] [Related]
17. Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2.
Purandare AV; McDevitt TM; Wan H; You D; Penhallow B; Han X; Vuppugalla R; Zhang Y; Ruepp SU; Trainor GL; Lombardo L; Pedicord D; Gottardis MM; Ross-Macdonald P; de Silva H; Hosbach J; Emanuel SL; Blat Y; Fitzpatrick E; Taylor TL; McIntyre KW; Michaud E; Mulligan C; Lee FY; Woolfson A; Lasho TL; Pardanani A; Tefferi A; Lorenzi MV
Leukemia; 2012 Feb; 26(2):280-8. PubMed ID: 22015772
[TBL] [Abstract][Full Text] [Related]
18. The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3.
Lee SM; Yoon KB; Lee HJ; Kim J; Chung YK; Cho WJ; Mukai C; Choi S; Kang KW; Han SY; Ko H; Kim YC
Bioorg Med Chem; 2016 Nov; 24(21):5036-5046. PubMed ID: 27555284
[TBL] [Abstract][Full Text] [Related]
19. Single cell network profiling (SCNP): mapping drug and target interactions.
Covey TM; Putta S; Cesano A
Assay Drug Dev Technol; 2010 Jun; 8(3):321-43. PubMed ID: 20158439
[TBL] [Abstract][Full Text] [Related]
20. Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation.
Funakoshi-Tago M; Tago K; Nishizawa C; Takahashi K; Mashino T; Iwata S; Inoue H; Sonoda Y; Kasahara T
Biochem Pharmacol; 2008 Dec; 76(12):1681-93. PubMed ID: 18848530
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
