BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 23344974)

  • 61. A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
    Kozlyuk N; Gilston BA; Salay LE; Gogliotti RD; Christov PP; Kim K; Ovee M; Waterson AG; Chazin WJ
    Proteins; 2021 Nov; 89(11):1399-1412. PubMed ID: 34156100
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.
    Li Y; He Y; Luo Y
    Acta Crystallogr D Biol Crystallogr; 2009 Jun; 65(Pt 6):602-10. PubMed ID: 19465774
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51.
    Draxler SW; Bauer M; Eickmeier C; Nadal S; Nar H; Rangel Rojas D; Seeliger D; Zeeb M; Fiegen D
    J Med Chem; 2020 Jun; 63(11):5856-5864. PubMed ID: 32420743
    [TBL] [Abstract][Full Text] [Related]  

  • 64. NMR characterization of weak interactions between RhoGDI2 and fragment screening hits.
    Liu J; Gao J; Li F; Ma R; Wei Q; Wang A; Wu J; Ruan K
    Biochim Biophys Acta Gen Subj; 2017 Jan; 1861(1 Pt A):3061-3070. PubMed ID: 27721047
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Crystallographic fragment-based drug discovery: use of a brominated fragment library targeting HIV protease.
    Tiefenbrunn T; Forli S; Happer M; Gonzalez A; Tsai Y; Soltis M; Elder JH; Olson AJ; Stout CD
    Chem Biol Drug Des; 2014 Feb; 83(2):141-8. PubMed ID: 23998903
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Roles of the human Rad51 L1 and L2 loops in DNA binding.
    Matsuo Y; Sakane I; Takizawa Y; Takahashi M; Kurumizaka H
    FEBS J; 2006 Jul; 273(14):3148-59. PubMed ID: 16780572
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity.
    Chatterjee G; Jimenez-Sainz J; Presti T; Nguyen T; Jensen RB
    Nucleic Acids Res; 2016 Jun; 44(11):5256-70. PubMed ID: 27084934
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Identification of Rad51 regulation by BRCA2 using Caenorhabditis elegans BRCA2 and bimolecular fluorescence complementation analysis.
    Min J; Park PG; Ko E; Choi E; Lee H
    Biochem Biophys Res Commun; 2007 Nov; 362(4):958-64. PubMed ID: 17767921
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins.
    Chen LT; Ko TP; Chang YC; Lin KA; Chang CS; Wang AH; Wang TF
    Nucleic Acids Res; 2007; 35(6):1787-801. PubMed ID: 17329376
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
    Kolinjivadi AM; Sannino V; De Antoni A; Zadorozhny K; Kilkenny M; Técher H; Baldi G; Shen R; Ciccia A; Pellegrini L; Krejci L; Costanzo V
    Mol Cell; 2017 Sep; 67(5):867-881.e7. PubMed ID: 28757209
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum.
    Genois MM; Mukherjee A; Ubeda JM; Buisson R; Paquet E; Roy G; Plourde M; Coulombe Y; Ouellette M; Masson JY
    Nucleic Acids Res; 2012 Aug; 40(14):6570-84. PubMed ID: 22505581
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.
    Esashi F; Galkin VE; Yu X; Egelman EH; West SC
    Nat Struct Mol Biol; 2007 Jun; 14(6):468-74. PubMed ID: 17515904
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Analysis of cooperativity by isothermal titration calorimetry.
    Brown A
    Int J Mol Sci; 2009 Aug; 10(8):3457-77. PubMed ID: 20111687
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway.
    Chun J; Buechelmaier ES; Powell SN
    Mol Cell Biol; 2013 Jan; 33(2):387-95. PubMed ID: 23149936
    [TBL] [Abstract][Full Text] [Related]  

  • 75. The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.
    Zhao W; Wiese C; Kwon Y; Hromas R; Sung P
    Annu Rev Biochem; 2019 Jun; 88():221-245. PubMed ID: 30917004
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Biophysical and computational fragment-based approaches to targeting protein-protein interactions: applications in structure-guided drug discovery.
    Winter A; Higueruelo AP; Marsh M; Sigurdardottir A; Pitt WR; Blundell TL
    Q Rev Biophys; 2012 Nov; 45(4):383-426. PubMed ID: 22971516
    [TBL] [Abstract][Full Text] [Related]  

  • 77. A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.
    Luo K; Li L; Li Y; Wu C; Yin Y; Chen Y; Deng M; Nowsheen S; Yuan J; Lou Z
    Genes Dev; 2016 Dec; 30(23):2581-2595. PubMed ID: 27941124
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Conformational flexibility revealed by the crystal structure of a crenarchaeal RadA.
    Ariza A; Richard DJ; White MF; Bond CS
    Nucleic Acids Res; 2005; 33(5):1465-73. PubMed ID: 15755748
    [TBL] [Abstract][Full Text] [Related]  

  • 79. The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction.
    Yang H; Li Q; Fan J; Holloman WK; Pavletich NP
    Nature; 2005 Feb; 433(7026):653-7. PubMed ID: 15703751
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Sulfolobus tokodaii RadA paralog, stRadC2, is involved in DNA recombination via interaction with RadA and Hjc.
    Wang L; Sheng D; Han W; Huang B; Zhu S; Ni J; Li J; Shen Y
    Sci China Life Sci; 2012 Mar; 55(3):261-7. PubMed ID: 22437993
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.