BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 23350987)

  • 1. Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.
    Neill T; Jones HR; Crane-Smith Z; Owens RT; Schaefer L; Iozzo RV
    FEBS J; 2013 May; 280(10):2353-68. PubMed ID: 23350987
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
    Neill T; Painter H; Buraschi S; Owens RT; Lisanti MP; Schaefer L; Iozzo RV
    J Biol Chem; 2012 Feb; 287(8):5492-506. PubMed ID: 22194599
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
    Nakashima M; Adachi S; Yasuda I; Yamauchi T; Kawaguchi J; Hanamatsu T; Yoshioka T; Okano Y; Hirose Y; Kozawa O; Moriwaki H
    Mol Cancer; 2011 Jul; 10():79. PubMed ID: 21722395
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin.
    Neill T; Torres A; Buraschi S; Owens RT; Hoek JB; Baffa R; Iozzo RV
    J Biol Chem; 2014 Feb; 289(8):4952-68. PubMed ID: 24403067
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Decorin as a multivalent therapeutic agent against cancer.
    Neill T; Schaefer L; Iozzo RV
    Adv Drug Deliv Rev; 2016 Feb; 97():174-85. PubMed ID: 26522384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells.
    Du S; Wang S; Wu Q; Hu J; Li T
    Exp Eye Res; 2013 Nov; 116():151-60. PubMed ID: 24016866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel role of Rho-kinase in the regulation of ligand-induced phosphorylated EGFR endocytosis via the early/late endocytic pathway in human fibrosarcoma cells.
    Nishimura Y; Bereczky B; Yoshioka K; Taniguchi S; Itoh K
    J Mol Histol; 2011 Oct; 42(5):427-42. PubMed ID: 21847509
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA.
    Edlund S; Landström M; Heldin CH; Aspenström P
    Mol Biol Cell; 2002 Mar; 13(3):902-14. PubMed ID: 11907271
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.
    Buraschi S; Neill T; Owens RT; Iniguez LA; Purkins G; Vadigepalli R; Evans B; Schaefer L; Peiper SC; Wang ZX; Iozzo RV
    PLoS One; 2012; 7(9):e45559. PubMed ID: 23029096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RhoA as a mediator of clinically relevant androgen action in prostate cancer cells.
    Schmidt LJ; Duncan K; Yadav N; Regan KM; Verone AR; Lohse CM; Pop EA; Attwood K; Wilding G; Mohler JL; Sebo TJ; Tindall DJ; Heemers HV
    Mol Endocrinol; 2012 May; 26(5):716-35. PubMed ID: 22456196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.
    Takata K; Morishige K; Takahashi T; Hashimoto K; Tsutsumi S; Yin L; Ohta T; Kawagoe J; Takahashi K; Kurachi H
    Mol Cancer Ther; 2008 Jun; 7(6):1551-61. PubMed ID: 18566226
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial Cells.
    Hauke M; Eckenstaler R; Ripperger A; Ender A; Braun H; Benndorf RA
    J Am Heart Assoc; 2022 Jun; 11(12):e025119. PubMed ID: 35699166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasion.
    Bourguignon LY; Wong G; Earle C; Krueger K; Spevak CC
    J Biol Chem; 2010 Nov; 285(47):36721-35. PubMed ID: 20843787
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Catabolic degradation of endothelial VEGFA via autophagy.
    Neill T; Chen CG; Buraschi S; Iozzo RV
    J Biol Chem; 2020 May; 295(18):6064-6079. PubMed ID: 32209654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells.
    Ohta T; Takahashi T; Shibuya T; Amita M; Henmi N; Takahashi K; Kurachi H
    Cancer Biol Ther; 2012 Jan; 13(1):25-33. PubMed ID: 22336585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ADAM12 Is a Novel Regulator of Tumor Angiogenesis via STAT3 Signaling.
    Roy R; Dagher A; Butterfield C; Moses MA
    Mol Cancer Res; 2017 Nov; 15(11):1608-1622. PubMed ID: 28765266
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.
    Buraschi S; Pal N; Tyler-Rubinstein N; Owens RT; Neill T; Iozzo RV
    J Biol Chem; 2010 Dec; 285(53):42075-85. PubMed ID: 20974860
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy.
    Neill T; Sharpe C; Owens RT; Iozzo RV
    J Biol Chem; 2017 Sep; 292(39):16211-16220. PubMed ID: 28798237
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Elevated phosphatase of regenerating liver 3 (PRL-3) promotes cytoskeleton reorganization, cell migration and invasion in endometrial stromal cells from endometrioma.
    Zhan H; Ma J; Ruan F; Bedaiwy MA; Peng B; Wu R; Lin J
    Hum Reprod; 2016 Apr; 31(4):723-33. PubMed ID: 26874360
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An anti-oncogenic role for decorin. Down-regulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells.
    Santra M; Eichstetter I; Iozzo RV
    J Biol Chem; 2000 Nov; 275(45):35153-61. PubMed ID: 10942781
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.