BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 23354837)

  • 1. Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
    Atkinson SC; Dogovski C; Downton MT; Czabotar PE; Dobson RC; Gerrard JA; Wagner J; Perugini MA
    Plant Mol Biol; 2013 Mar; 81(4-5):431-46. PubMed ID: 23354837
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine.
    Atkinson SC; Dogovski C; Downton MT; Pearce FG; Reboul CF; Buckle AM; Gerrard JA; Dobson RC; Wagner J; Perugini MA
    PLoS One; 2012; 7(6):e38318. PubMed ID: 22761676
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera.
    Atkinson SC; Dogovski C; Newman J; Dobson RC; Perugini MA
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2011 Dec; 67(Pt 12):1537-41. PubMed ID: 22139160
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.
    Conly CJ; Skovpen YV; Li S; Palmer DR; Sanders DA
    Biochemistry; 2014 Dec; 53(47):7396-406. PubMed ID: 25369463
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target.
    Soares da Costa TP; Desbois S; Dogovski C; Gorman MA; Ketaren NE; Paxman JJ; Siddiqui T; Zammit LM; Abbott BM; Robins-Browne RM; Parker MW; Jameson GB; Hall NE; Panjikar S; Perugini MA
    Structure; 2016 Aug; 24(8):1282-1291. PubMed ID: 27427481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase.
    Reboul CF; Porebski BT; Griffin MD; Dobson RC; Perugini MA; Gerrard JA; Buckle AM
    PLoS Comput Biol; 2012; 8(6):e1002537. PubMed ID: 22685390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
    Kefala G; Evans GL; Griffin MD; Devenish SR; Pearce FG; Perugini MA; Gerrard JA; Weiss MS; Dobson RC
    Biochem J; 2008 Apr; 411(2):351-60. PubMed ID: 18062777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.
    Domigan LJ; Scally SW; Fogg MJ; Hutton CA; Perugini MA; Dobson RC; Muscroft-Taylor AC; Gerrard JA; Devenish SR
    Biochim Biophys Acta; 2009 Oct; 1794(10):1510-6. PubMed ID: 19595801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis.
    Wolterink-van Loo S; Levisson M; Cabrières MC; Franssen MC; van der Oost J
    Extremophiles; 2008 May; 12(3):461-9. PubMed ID: 18340401
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana.
    Griffin MD; Billakanti JM; Wason A; Keller S; Mertens HD; Atkinson SC; Dobson RC; Perugini MA; Gerrard JA; Pearce FG
    PLoS One; 2012; 7(7):e40318. PubMed ID: 22792278
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
    Dobson RC; Griffin MD; Jameson GB; Gerrard JA
    Acta Crystallogr D Biol Crystallogr; 2005 Aug; 61(Pt 8):1116-24. PubMed ID: 16041077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Feedback inhibition of dihydrodipicolinate synthase enzymes by L-lysine.
    Blickling S; Knäblein J
    Biol Chem; 1997; 378(3-4):207-10. PubMed ID: 9165072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
    Soares da Costa TP; Muscroft-Taylor AC; Dobson RC; Devenish SR; Jameson GB; Gerrard JA
    Biochimie; 2010 Jul; 92(7):837-45. PubMed ID: 20353808
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dihydrodipicolinate synthase from Campylobacter jejuni: kinetic mechanism of cooperative allosteric inhibition and inhibitor-induced substrate cooperativity.
    Skovpen YV; Palmer DR
    Biochemistry; 2013 Aug; 52(32):5454-62. PubMed ID: 23902434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isothermal titration microcalorimetry reveals the cooperative and noncompetitive nature of inhibition of Sinorhizobium meliloti L5-30 dihydrodipicolinate synthase by (S)-lysine.
    Phenix CP; Palmer DR
    Biochemistry; 2008 Jul; 47(30):7779-81. PubMed ID: 18605698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.
    Dobson RC; Griffin MD; Devenish SR; Pearce FG; Hutton CA; Gerrard JA; Jameson GB; Perugini MA
    Protein Sci; 2008 Dec; 17(12):2080-90. PubMed ID: 18787203
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure and in silico studies of dihydrodipicolinate synthase (DHDPS) from Aquifex aeolicus.
    Sridharan U; Ebihara A; Kuramitsu S; Yokoyama S; Kumarevel T; Ponnuraj K
    Extremophiles; 2014 Nov; 18(6):973-85. PubMed ID: 24996798
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dihydrodipicolinate synthase from Thermotoga maritima.
    Pearce FG; Perugini MA; McKerchar HJ; Gerrard JA
    Biochem J; 2006 Dec; 400(2):359-66. PubMed ID: 16872276
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate.
    Dobson RC; Griffin MD; Roberts SJ; Gerrard JA
    Biochimie; 2004; 86(4-5):311-5. PubMed ID: 15194235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production.
    Geng F; Chen Z; Zheng P; Sun J; Zeng AP
    Appl Microbiol Biotechnol; 2013 Mar; 97(5):1963-71. PubMed ID: 22644522
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.