BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

342 related articles for article (PubMed ID: 23355008)

  • 1. Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus.
    Krishnan K; Feng X; Powers-Fletcher MV; Bick G; Richie DL; Woollett LA; Askew DS
    Eukaryot Cell; 2013 Apr; 12(4):512-9. PubMed ID: 23355008
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR).
    Richie DL; Feng X; Hartl L; Aimanianda V; Krishnan K; Powers-Fletcher MV; Watson DS; Galande AK; White SM; Willett T; Latgé JP; Rhodes JC; Askew DS
    Virulence; 2011; 2(1):12-21. PubMed ID: 21217201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus.
    Guirao-Abad JP; Weichert M; Luengo-Gil G; Sze Wah Wong S; Aimanianda V; Grisham C; Malev N; Reddy S; Woollett L; Askew DS
    mBio; 2021 Oct; 12(5):e0273521. PubMed ID: 34663092
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca
    Weichert M; Guirao-Abad J; Aimanianda V; Krishnan K; Grisham C; Snyder P; Sheehan A; Abbu RR; Liu H; Filler SG; Gruenstein EI; Latgé JP; Askew DS
    mBio; 2020 Jun; 11(3):. PubMed ID: 32487759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.
    Feng X; Krishnan K; Richie DL; Aimanianda V; Hartl L; Grahl N; Powers-Fletcher MV; Zhang M; Fuller KK; Nierman WC; Lu LJ; Latgé JP; Woollett L; Newman SL; Cramer RA; Rhodes JC; Askew DS
    PLoS Pathog; 2011 Oct; 7(10):e1002330. PubMed ID: 22028661
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components.
    Raj S; Krishnan K; Askew DS; Helynck O; Suzanne P; Lesnard A; Rault S; Zeidler U; d'Enfert C; Latgé JP; Munier-Lehmann H; Saveanu C
    Antimicrob Agents Chemother; 2015 Dec; 60(3):1438-49. PubMed ID: 26666917
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Erg4A and Erg4B Are Required for Conidiation and Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus.
    Long N; Xu X; Zeng Q; Sang H; Lu L
    Appl Environ Microbiol; 2017 Feb; 83(4):. PubMed ID: 27986720
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SREBP-dependent triazole susceptibility in Aspergillus fumigatus is mediated through direct transcriptional regulation of erg11A (cyp51A).
    Blosser SJ; Cramer RA
    Antimicrob Agents Chemother; 2012 Jan; 56(1):248-57. PubMed ID: 22006005
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Aspergillus fumigatus pkcA G579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model.
    Rocha MC; Godoy KF; de Castro PA; Hori JI; Bom VL; Brown NA; Cunha AF; Goldman GH; Malavazi I
    PLoS One; 2015; 10(8):e0135195. PubMed ID: 26295576
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic reticulum-associated degradation mediated by MoHrd1 and MoDer1 is pivotal for appressorium development and pathogenicity of Magnaporthe oryzae.
    Tang W; Jiang H; Aron O; Wang M; Wang X; Chen J; Lin B; Chen X; Zheng Q; Gao X; He D; Wang A; Wang Z
    Environ Microbiol; 2020 Dec; 22(12):4953-4973. PubMed ID: 32410295
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dsc orthologs are required for hypoxia adaptation, triazole drug responses, and fungal virulence in Aspergillus fumigatus.
    Willger SD; Cornish EJ; Chung D; Fleming BA; Lehmann MM; Puttikamonkul S; Cramer RA
    Eukaryot Cell; 2012 Dec; 11(12):1557-67. PubMed ID: 23104569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein.
    Fujikawa K; Nakahara K; Takasugi N; Nishiya T; Ito A; Uchida K; Uehara T
    Biochem Biophys Res Commun; 2020 Apr; 524(4):910-915. PubMed ID: 32051088
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence.
    Vaknin Y; Hillmann F; Iannitti R; Ben Baruch N; Sandovsky-Losica H; Shadkchan Y; Romani L; Brakhage A; Kniemeyer O; Osherov N
    Infect Immun; 2016 Jun; 84(6):1866-1878. PubMed ID: 27068092
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus.
    Powers-Fletcher MV; Jambunathan K; Brewer JL; Krishnan K; Feng X; Galande AK; Askew DS
    PLoS One; 2011; 6(12):e28865. PubMed ID: 22163332
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy is dispensable to overcome ER stress in the filamentous fungus Aspergillus niger.
    Burggraaf AM; Ram AF
    Microbiologyopen; 2016 Aug; 5(4):647-58. PubMed ID: 27027276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
    Shi J; Hu X; Guo Y; Wang L; Ji J; Li J; Zhang ZR
    J Biol Chem; 2019 Dec; 294(52):20084-20096. PubMed ID: 31748412
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glycosylation-independent ERAD pathway serves as a backup system under ER stress.
    Ushioda R; Hoseki J; Nagata K
    Mol Biol Cell; 2013 Oct; 24(20):3155-63. PubMed ID: 23966469
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus Aspergillus fumigatus and Suggests Noncanonical Functions within the Pathway.
    Guirao-Abad JP; Weichert M; Albee A; Deck K; Askew DS
    mSphere; 2020 Oct; 5(5):. PubMed ID: 33087521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A sphingolipid synthesis-related protein OrmA in Aspergillus fumigatus is responsible for azole susceptibility and virulence.
    Zhai P; Song J; Gao L; Lu L
    Cell Microbiol; 2019 Dec; 21(12):e13092. PubMed ID: 31376233
    [TBL] [Abstract][Full Text] [Related]  

  • 20. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
    Harada K; Kato M; Nakamura N
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.