BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 2335526)

  • 1. Identification and characterization of a mutation in the dihydrofolate reductase gene from the methotrexate-resistant Chinese hamster ovary cell line Pro-3 MtxRIII.
    Dicker AP; Volkenandt M; Schweitzer BI; Banerjee D; Bertino JR
    J Biol Chem; 1990 May; 265(14):8317-21. PubMed ID: 2335526
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells.
    McIvor RS; Simonsen CC
    Nucleic Acids Res; 1990 Dec; 18(23):7025-32. PubMed ID: 2263462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amplification of a polymorphic dihydrofolate reductase gene expressing an enzyme with decreased binding to methotrexate in a human colon carcinoma cell line, HCT-8R4, resistant to this drug.
    Srimatkandada S; Schweitzer BI; Moroson BA; Dube S; Bertino JR
    J Biol Chem; 1989 Feb; 264(6):3524-8. PubMed ID: 2914962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line.
    Neumann K; Al-Batayneh KM; Kuiper MJ; Parsons-Sheldrake J; Tyshenko MG; Flintoff WF; Cole SP; Walker VK
    Genome; 2003 Aug; 46(4):707-15. PubMed ID: 12897877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation.
    Dicker AP; Waltham MC; Volkenandt M; Schweitzer BI; Otter GM; Schmid FA; Sirotnak FM; Bertino JR
    Proc Natl Acad Sci U S A; 1993 Dec; 90(24):11797-801. PubMed ID: 8265628
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.
    Milbrandt JD; Heintz NH; White WC; Rothman SM; Hamlin JL
    Proc Natl Acad Sci U S A; 1981 Oct; 78(10):6043-7. PubMed ID: 6273843
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transfection of DHFR- and DHFR+ mammalian cells using methotrexate-resistant mutants of mouse dihydrofolate reductase.
    Thillet J; Pictet R
    FEBS Lett; 1990 Sep; 269(2):450-3. PubMed ID: 2401371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation and characterization of a dihydrofolate reductase gene mutation in methotrexate-resistant Drosophila cells.
    Hao H; Tyshenko MG; Walker VK
    Gene Expr; 1996; 6(4):231-9. PubMed ID: 9196078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Saturation mutagenesis at dihydrofolate reductase codons 22 and 31. A variety of amino acid substitutions conferring methotrexate resistance.
    Morris JA; McIvor RS
    Biochem Pharmacol; 1994 Mar; 47(7):1207-20. PubMed ID: 8161350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim.
    Thillet J; Absil J; Stone SR; Pictet R
    J Biol Chem; 1988 Sep; 263(25):12500-8. PubMed ID: 3045118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Similar 150-kilobase DNA sequences are amplified in independently derived methotrexate-resistant Chinese hamster cells.
    Montoya-Zavala M; Hamlin JL
    Mol Cell Biol; 1985 Apr; 5(4):619-27. PubMed ID: 2985962
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of abbreviated mouse dihydrofolate reductase genes in cultured hamster cells.
    Gasser CS; Simonsen CC; Schilling JW; Schimke RT
    Proc Natl Acad Sci U S A; 1982 Nov; 79(21):6522-6. PubMed ID: 6959133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transfection with a cDNA encoding a Ser31 or Ser34 mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance.
    Banerjee D; Schweitzer BI; Volkenandt M; Li MX; Waltham M; Mineishi S; Zhao SC; Bertino JR
    Gene; 1994 Feb; 139(2):269-74. PubMed ID: 8112617
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and characterization of a gene that is coamplified with dihydrofolate reductase in a methotrexate-resistant CHO cell line.
    Foreman PK; Hamlin JL
    Mol Cell Biol; 1989 Mar; 9(3):1137-47. PubMed ID: 2725490
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overproduction of dihydrofolate reductase and gene amplification in methotrexate-resistant Chinese hamster ovary cells.
    Flintoff WF; Weber MK; Nagainis CR; Essani AK; Robertson D; Salser W
    Mol Cell Biol; 1982 Mar; 2(3):275-85. PubMed ID: 6287233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
    Affleck JG; Al-Batayneh KM; Neumann K; Cole SP; Walker VK
    Eur J Pharmacol; 2006 Jan; 529(1-3):71-8. PubMed ID: 16325803
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene.
    Flintoff WF; Livingston E; Duff C; Worton RG
    Mol Cell Biol; 1984 Jan; 4(1):69-76. PubMed ID: 6700586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Allelic variation in the dihydrofolate reductase gene at amino acid position 95 contributes to antifolate resistance in Chinese hamster cells.
    Yu M; Melera PW
    Cancer Res; 1993 Dec; 53(24):6031-5. PubMed ID: 8261418
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amplification of a cloned Chinese hamster dihydrofolate reductase gene after transfer into a dihydrofolate reductase-deficient cell line.
    Milbrandt JD; Azizkhan JC; Hamlin JL
    Mol Cell Biol; 1983 Jul; 3(7):1274-82. PubMed ID: 6310371
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Detection of a single base mutation in the human dihydrofolate reductase gene from a methotrexate-resistant cell line using the polymerase chain reaction.
    Dicker AP; Volkenandt M; Bertino JR
    Cancer Commun; 1989; 1(1):7-12. PubMed ID: 2640157
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.