BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 23358144)

  • 1. Differential mRNA expression and the uptake of methotrexate in primary MAEC and MLF cells: involvement of the Abc and Slco/Oatp transporters in alveolar epithelial cell toxicity.
    Ohbayashi M; Yamamoto C; Shiozawa A; Kohyama N; Kobayashi Y; Yamamoto T
    J Toxicol Sci; 2013 Feb; 38(1):103-14. PubMed ID: 23358144
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models.
    Endter S; Francombe D; Ehrhardt C; Gumbleton M
    J Pharm Pharmacol; 2009 May; 61(5):583-91. PubMed ID: 19405996
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.
    Ohbayashi M; Suzuki M; Yashiro Y; Fukuwaka S; Yasuda M; Kohyama N; Kobayashi Y; Yamamoto T
    J Toxicol Sci; 2010 Oct; 35(5):653-61. PubMed ID: 20930460
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps).
    Cheng X; Maher J; Chen C; Klaassen CD
    Drug Metab Dispos; 2005 Jul; 33(7):1062-73. PubMed ID: 15843488
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of methotrexate treatment on expression levels of multidrug resistance protein 2, breast cancer resistance protein and organic anion transporters Oat1, Oat2 and Oat3 in rats.
    Shibayama Y; Ushinohama K; Ikeda R; Yoshikawa Y; Motoya T; Takeda Y; Yamada K
    Cancer Sci; 2006 Nov; 97(11):1260-6. PubMed ID: 16925582
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate.
    Patik I; Kovacsics D; Német O; Gera M; Várady G; Stieger B; Hagenbuch B; Szakács G; Özvegy-Laczka C
    Biochem Pharmacol; 2015 Dec; 98(4):649-58. PubMed ID: 26415544
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methotrexate Disposition in Pediatric Patients with Acute Lymphoblastic Leukemia: What Have We Learnt From the Genetic Variants of Drug Transporters.
    Hu YH; Zhou L; Wang SS; Jing X; Guo HL; Sun F; Zhang Y; Chen F; Xu J; Ji X
    Curr Pharm Des; 2019; 25(6):627-634. PubMed ID: 30931851
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells.
    Seithel A; Karlsson J; Hilgendorf C; Björquist A; Ungell AL
    Eur J Pharm Sci; 2006 Jul; 28(4):291-9. PubMed ID: 16704924
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of transport mechanisms of methotrexate in human choriocarcinoma cell lines by LC-MS/MS.
    Bai M; Shen Q; Wu Y; Ma Z; Wang Y; Chen M; Liu D; Zhou L
    J Pharm Biomed Anal; 2024 Sep; 247():116268. PubMed ID: 38823222
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic knockdown of a single organic anion transporter alters the expression of functionally related genes in Malpighian tubules of Drosophila melanogaster.
    Chahine S; Campos A; O'Donnell MJ
    J Exp Biol; 2012 Aug; 215(Pt 15):2601-10. PubMed ID: 22786636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effects of drug transporters on the efficacy of methotrexate in the treatment of rheumatoid arthritis.
    Gao J; Wang C; Wei W
    Life Sci; 2021 Mar; 268():118907. PubMed ID: 33428880
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
    Cheng X; Maher J; Dieter MZ; Klaassen CD
    Drug Metab Dispos; 2005 Sep; 33(9):1276-82. PubMed ID: 15919853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants.
    Badagnani I; Castro RA; Taylor TR; Brett CM; Huang CC; Stryke D; Kawamoto M; Johns SJ; Ferrin TE; Carlson EJ; Burchard EG; Giacomini KM
    J Pharmacol Exp Ther; 2006 Aug; 318(2):521-9. PubMed ID: 16702441
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).
    van de Steeg E; van der Kruijssen CM; Wagenaar E; Burggraaff JE; Mesman E; Kenworthy KE; Schinkel AH
    Drug Metab Dispos; 2009 Feb; 37(2):277-81. PubMed ID: 19022939
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology.
    Wu ZT; Yao D; Ji SY; Ni X; Gao YM; Hui LJ; Pan GY
    Cell Physiol Biochem; 2016; 38(5):1815-30. PubMed ID: 27160211
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of multidrug resistance-associated protein mRNAs expression profiles in Caco-2 and HT-1080 cell lines induced by methotrexate.
    Ikeda K; Myotoku M; Hirotani Y
    Pharmazie; 2008 Dec; 63(12):883-9. PubMed ID: 19177904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.
    Jørgensen L; Van Beek J; Lund S; Schousboe A; Badolo L
    Eur J Pharm Sci; 2007 Feb; 30(2):181-9. PubMed ID: 17174077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methotrexate influx via folate transporters into alveolar epithelial cell line A549.
    Kawami M; Miyamoto M; Yumoto R; Takano M
    Drug Metab Pharmacokinet; 2015 Aug; 30(4):276-81. PubMed ID: 26190800
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.
    Durmus S; Lozano-Mena G; van Esch A; Wagenaar E; van Tellingen O; Schinkel AH
    Mol Pharm; 2015 Dec; 12(12):4259-69. PubMed ID: 26474710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells.
    Sato K; Seki T; Mizutani A; Muranaka Y; Hirota S; Nishi K; Yamazaki K; Nishii R; Nakanishi T; Tamai I; Kawai K; Kobayashi M
    Front Pharmacol; 2022; 13():1069321. PubMed ID: 36712667
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.