These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 23363599)

  • 1. Means of self-preservation: how an intrinsically disordered ubiquitin-protein ligase averts self-destruction.
    Fredrickson EK; Clowes Candadai SV; Tam CH; Gardner RG
    Mol Biol Cell; 2013 Apr; 24(7):1041-52. PubMed ID: 23363599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation.
    Amm I; Wolf DH
    FEBS Lett; 2016 Jun; 590(12):1765-75. PubMed ID: 27173001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The San1 Ubiquitin Ligase Functions Preferentially with Ubiquitin-conjugating Enzyme Ubc1 during Protein Quality Control.
    Ibarra R; Sandoval D; Fredrickson EK; Gardner RG; Kleiger G
    J Biol Chem; 2016 Sep; 291(36):18778-90. PubMed ID: 27405755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exposed hydrophobicity is a key determinant of nuclear quality control degradation.
    Fredrickson EK; Rosenbaum JC; Locke MN; Milac TI; Gardner RG
    Mol Biol Cell; 2011 Jul; 22(13):2384-95. PubMed ID: 21551067
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How a disordered ubiquitin ligase maintains order in nuclear protein homeostasis.
    Rosenbaum JC; Gardner RG
    Nucleus; 2011; 2(4):264-70. PubMed ID: 21941105
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate recognition in nuclear protein quality control degradation is governed by exposed hydrophobicity that correlates with aggregation and insolubility.
    Fredrickson EK; Gallagher PS; Clowes Candadai SV; Gardner RG
    J Biol Chem; 2013 Mar; 288(9):6130-9. PubMed ID: 23335508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein quality control degron-containing substrates are differentially targeted in the cytoplasm and nucleus by ubiquitin ligases.
    Hickey CM; Breckel C; Zhang M; Theune WC; Hochstrasser M
    Genetics; 2021 Mar; 217(1):1-19. PubMed ID: 33683364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.
    Guharoy M; Bhowmick P; Tompa P
    J Biol Chem; 2016 Mar; 291(13):6723-31. PubMed ID: 26851277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Cdc48 Complex Alleviates the Cytotoxicity of Misfolded Proteins by Regulating Ubiquitin Homeostasis.
    Higgins R; Kabbaj MH; Sherwin D; Howell LA; Hatcher A; Tomko RJ; Wang Y
    Cell Rep; 2020 Jul; 32(2):107898. PubMed ID: 32668237
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural insights into Ubr1-mediated N-degron polyubiquitination.
    Pan M; Zheng Q; Wang T; Liang L; Mao J; Zuo C; Ding R; Ai H; Xie Y; Si D; Yu Y; Liu L; Zhao M
    Nature; 2021 Dec; 600(7888):334-338. PubMed ID: 34789879
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HUWE1 ubiquitinates MyoD and targets it for proteasomal degradation.
    Noy T; Suad O; Taglicht D; Ciechanover A
    Biochem Biophys Res Commun; 2012 Feb; 418(2):408-13. PubMed ID: 22277673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The requirement for Cdc48/p97 in nuclear protein quality control degradation depends on the substrate and correlates with substrate insolubility.
    Gallagher PS; Clowes Candadai SV; Gardner RG
    J Cell Sci; 2014 May; 127(Pt 9):1980-91. PubMed ID: 24569878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the San1 ubiquitin ligase in the heat stress-induced degradation of nonnative Nup1 in the nuclear pore complex.
    Ikeda T; Yamazaki K; Okumura F; Kamura T; Nakatsukasa K
    Genetics; 2024 Apr; 226(4):. PubMed ID: 38302116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.
    Boomsma W; Nielsen SV; Lindorff-Larsen K; Hartmann-Petersen R; Ellgaard L
    PeerJ; 2016; 4():e1725. PubMed ID: 26966660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.
    Eisele F; Wolf DH
    FEBS Lett; 2008 Dec; 582(30):4143-6. PubMed ID: 19041308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase.
    Kong KE; Fischer B; Meurer M; Kats I; Li Z; Rühle F; Barry JD; Kirrmaier D; Chevyreva V; San Luis BJ; Costanzo M; Huber W; Andrews BJ; Boone C; Knop M; Khmelinskii A
    Mol Cell; 2021 Jun; 81(11):2460-2476.e11. PubMed ID: 33974913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate.
    Jones RD; Enam C; Ibarra R; Borror HR; Mostoller KE; Fredrickson EK; Lin J; Chuang E; March Z; Shorter J; Ravid T; Kleiger G; Gardner RG
    Mol Biol Cell; 2020 Feb; 31(3):221-233. PubMed ID: 31825716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sir Antagonist 1 (San1) is a ubiquitin ligase.
    Dasgupta A; Ramsey KL; Smith JS; Auble DT
    J Biol Chem; 2004 Jun; 279(26):26830-8. PubMed ID: 15078868
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.
    Rosenbaum JC; Fredrickson EK; Oeser ML; Garrett-Engele CM; Locke MN; Richardson LA; Nelson ZW; Hetrick ED; Milac TI; Gottschling DE; Gardner RG
    Mol Cell; 2011 Jan; 41(1):93-106. PubMed ID: 21211726
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.