BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 23363599)

  • 1. Means of self-preservation: how an intrinsically disordered ubiquitin-protein ligase averts self-destruction.
    Fredrickson EK; Clowes Candadai SV; Tam CH; Gardner RG
    Mol Biol Cell; 2013 Apr; 24(7):1041-52. PubMed ID: 23363599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation.
    Amm I; Wolf DH
    FEBS Lett; 2016 Jun; 590(12):1765-75. PubMed ID: 27173001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The San1 Ubiquitin Ligase Functions Preferentially with Ubiquitin-conjugating Enzyme Ubc1 during Protein Quality Control.
    Ibarra R; Sandoval D; Fredrickson EK; Gardner RG; Kleiger G
    J Biol Chem; 2016 Sep; 291(36):18778-90. PubMed ID: 27405755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exposed hydrophobicity is a key determinant of nuclear quality control degradation.
    Fredrickson EK; Rosenbaum JC; Locke MN; Milac TI; Gardner RG
    Mol Biol Cell; 2011 Jul; 22(13):2384-95. PubMed ID: 21551067
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How a disordered ubiquitin ligase maintains order in nuclear protein homeostasis.
    Rosenbaum JC; Gardner RG
    Nucleus; 2011; 2(4):264-70. PubMed ID: 21941105
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate recognition in nuclear protein quality control degradation is governed by exposed hydrophobicity that correlates with aggregation and insolubility.
    Fredrickson EK; Gallagher PS; Clowes Candadai SV; Gardner RG
    J Biol Chem; 2013 Mar; 288(9):6130-9. PubMed ID: 23335508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein quality control degron-containing substrates are differentially targeted in the cytoplasm and nucleus by ubiquitin ligases.
    Hickey CM; Breckel C; Zhang M; Theune WC; Hochstrasser M
    Genetics; 2021 Mar; 217(1):1-19. PubMed ID: 33683364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.
    Guharoy M; Bhowmick P; Tompa P
    J Biol Chem; 2016 Mar; 291(13):6723-31. PubMed ID: 26851277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Cdc48 Complex Alleviates the Cytotoxicity of Misfolded Proteins by Regulating Ubiquitin Homeostasis.
    Higgins R; Kabbaj MH; Sherwin D; Howell LA; Hatcher A; Tomko RJ; Wang Y
    Cell Rep; 2020 Jul; 32(2):107898. PubMed ID: 32668237
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into Ubr1-mediated N-degron polyubiquitination.
    Pan M; Zheng Q; Wang T; Liang L; Mao J; Zuo C; Ding R; Ai H; Xie Y; Si D; Yu Y; Liu L; Zhao M
    Nature; 2021 Dec; 600(7888):334-338. PubMed ID: 34789879
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HUWE1 ubiquitinates MyoD and targets it for proteasomal degradation.
    Noy T; Suad O; Taglicht D; Ciechanover A
    Biochem Biophys Res Commun; 2012 Feb; 418(2):408-13. PubMed ID: 22277673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The requirement for Cdc48/p97 in nuclear protein quality control degradation depends on the substrate and correlates with substrate insolubility.
    Gallagher PS; Clowes Candadai SV; Gardner RG
    J Cell Sci; 2014 May; 127(Pt 9):1980-91. PubMed ID: 24569878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the San1 ubiquitin ligase in the heat stress-induced degradation of nonnative Nup1 in the nuclear pore complex.
    Ikeda T; Yamazaki K; Okumura F; Kamura T; Nakatsukasa K
    Genetics; 2024 Apr; 226(4):. PubMed ID: 38302116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.
    Boomsma W; Nielsen SV; Lindorff-Larsen K; Hartmann-Petersen R; Ellgaard L
    PeerJ; 2016; 4():e1725. PubMed ID: 26966660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.
    Eisele F; Wolf DH
    FEBS Lett; 2008 Dec; 582(30):4143-6. PubMed ID: 19041308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase.
    Kong KE; Fischer B; Meurer M; Kats I; Li Z; Rühle F; Barry JD; Kirrmaier D; Chevyreva V; San Luis BJ; Costanzo M; Huber W; Andrews BJ; Boone C; Knop M; Khmelinskii A
    Mol Cell; 2021 Jun; 81(11):2460-2476.e11. PubMed ID: 33974913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate.
    Jones RD; Enam C; Ibarra R; Borror HR; Mostoller KE; Fredrickson EK; Lin J; Chuang E; March Z; Shorter J; Ravid T; Kleiger G; Gardner RG
    Mol Biol Cell; 2020 Feb; 31(3):221-233. PubMed ID: 31825716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sir Antagonist 1 (San1) is a ubiquitin ligase.
    Dasgupta A; Ramsey KL; Smith JS; Auble DT
    J Biol Chem; 2004 Jun; 279(26):26830-8. PubMed ID: 15078868
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.
    Rosenbaum JC; Fredrickson EK; Oeser ML; Garrett-Engele CM; Locke MN; Richardson LA; Nelson ZW; Hetrick ED; Milac TI; Gottschling DE; Gardner RG
    Mol Cell; 2011 Jan; 41(1):93-106. PubMed ID: 21211726
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.