228 related articles for article (PubMed ID: 23364608)
1. Human electrophysiological and pharmacological properties of XEN-D0101: a novel atrial-selective Kv1.5/IKur inhibitor.
Ford J; Milnes J; Wettwer E; Christ T; Rogers M; Sutton K; Madge D; Virag L; Jost N; Horvath Z; Matschke K; Varro A; Ravens U
J Cardiovasc Pharmacol; 2013 May; 61(5):408-15. PubMed ID: 23364608
[TBL] [Abstract][Full Text] [Related]
2. The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.
Ford J; Milnes J; El Haou S; Wettwer E; Loose S; Matschke K; Tyl B; Round P; Ravens U
Heart Rhythm; 2016 Feb; 13(2):555-64. PubMed ID: 26455450
[TBL] [Abstract][Full Text] [Related]
3. Kv1.5 is an important component of repolarizing K+ current in canine atrial myocytes.
Fedida D; Eldstrom J; Hesketh JC; Lamorgese M; Castel L; Steele DF; Van Wagoner DR
Circ Res; 2003 Oct; 93(8):744-51. PubMed ID: 14500335
[TBL] [Abstract][Full Text] [Related]
4. Novel, potent inhibitors of human Kv1.5 K+ channels and ultrarapidly activating delayed rectifier potassium current.
Lagrutta A; Wang J; Fermini B; Salata JJ
J Pharmacol Exp Ther; 2006 Jun; 317(3):1054-63. PubMed ID: 16522807
[TBL] [Abstract][Full Text] [Related]
5. Revealing kinetics and state-dependent binding properties of I
Ellinwood N; Dobrev D; Morotti S; Grandi E
Chaos; 2017 Sep; 27(9):093918. PubMed ID: 28964116
[TBL] [Abstract][Full Text] [Related]
6. The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation.
Wettwer E; Christ T; Endig S; Rozmaritsa N; Matschke K; Lynch JJ; Pourrier M; Gibson JK; Fedida D; Knaut M; Ravens U
Cardiovasc Res; 2013 Apr; 98(1):145-54. PubMed ID: 23341576
[TBL] [Abstract][Full Text] [Related]
7. Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes.
Bachmann A; Gutcher I; Kopp K; Brendel J; Bosch RF; Busch AE; Gögelein H
Naunyn Schmiedebergs Arch Pharmacol; 2001 Nov; 364(5):472-8. PubMed ID: 11692231
[TBL] [Abstract][Full Text] [Related]
8. Raloxifene inhibits transient outward and ultra-rapid delayed rectifier potassium currents in human atrial myocytes.
Liu H; Jin MW; Xiang JZ; Huang Y; Sun HY; Chiu SW; Lau CP; Li GR
Eur J Pharmacol; 2007 Jun; 563(1-3):61-8. PubMed ID: 17337266
[TBL] [Abstract][Full Text] [Related]
9. Pathology-specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation.
Christ T; Wettwer E; Voigt N; Hála O; Radicke S; Matschke K; Várro A; Dobrev D; Ravens U
Br J Pharmacol; 2008 Aug; 154(8):1619-30. PubMed ID: 18536759
[TBL] [Abstract][Full Text] [Related]
10. Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.
Devalla HD; Schwach V; Ford JW; Milnes JT; El-Haou S; Jackson C; Gkatzis K; Elliott DA; Chuva de Sousa Lopes SM; Mummery CL; Verkerk AO; Passier R
EMBO Mol Med; 2015 Apr; 7(4):394-410. PubMed ID: 25700171
[TBL] [Abstract][Full Text] [Related]
11. Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation.
Wettwer E; Hála O; Christ T; Heubach JF; Dobrev D; Knaut M; Varró A; Ravens U
Circulation; 2004 Oct; 110(16):2299-306. PubMed ID: 15477405
[TBL] [Abstract][Full Text] [Related]
12. Inhibitory effects of hesperetin on Kv1.5 potassium channels stably expressed in HEK 293 cells and ultra-rapid delayed rectifier K(+) current in human atrial myocytes.
Wang H; Wang HF; Wang C; Chen YF; Ma R; Xiang JZ; Du XL; Tang Q
Eur J Pharmacol; 2016 Oct; 789():98-108. PubMed ID: 27397430
[TBL] [Abstract][Full Text] [Related]
13. Intravenous anesthetic propofol inhibits multiple human cardiac potassium channels.
Yang L; Liu H; Sun HY; Li GR
Anesthesiology; 2015 Mar; 122(3):571-84. PubMed ID: 25321870
[TBL] [Abstract][Full Text] [Related]
14. A double-blind, randomised, placebo-controlled, cross-over study assessing the use of XEN-D0103 in patients with paroxysmal atrial fibrillation and implanted pacemakers allowing continuous beat-to-beat monitoring of drug efficacy.
Shunmugam SR; Sugihara C; Freemantle N; Round P; Furniss S; Sulke N
J Interv Card Electrophysiol; 2018 Apr; 51(3):191-197. PubMed ID: 29460236
[TBL] [Abstract][Full Text] [Related]
15. Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito.
Turnow K; Metzner K; Cotella D; Morales MJ; Schaefer M; Christ T; Ravens U; Wettwer E; Kämmerer S
Basic Res Cardiol; 2015 Mar; 110(2):5. PubMed ID: 25600224
[TBL] [Abstract][Full Text] [Related]
16. Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation.
Baczko I; Liknes D; Yang W; Hamming KC; Searle G; Jaeger K; Husti Z; Juhasz V; Klausz G; Pap R; Saghy L; Varro A; Dolinsky V; Wang S; Rauniyar V; Hall D; Dyck JR; Light PE
Br J Pharmacol; 2014 Jan; 171(1):92-106. PubMed ID: 24102184
[TBL] [Abstract][Full Text] [Related]
17. Vernakalant does not alter early repolarization or contractility in normal and electrically remodelled atria.
van Hunnik A; Nasrallah H; Lau DH; Kuiper M; Verheule S; Schotten U
Europace; 2018 Jan; 20(1):140-148. PubMed ID: 28449044
[TBL] [Abstract][Full Text] [Related]
18. Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.
Knobloch K; Brendel J; Rosenstein B; Bleich M; Busch AE; Wirth KJ
Med Sci Monit; 2004 Jul; 10(7):BR221-8. PubMed ID: 15232496
[TBL] [Abstract][Full Text] [Related]
19. Altered Na(+) currents in atrial fibrillation effects of ranolazine on arrhythmias and contractility in human atrial myocardium.
Sossalla S; Kallmeyer B; Wagner S; Mazur M; Maurer U; Toischer K; Schmitto JD; Seipelt R; Schöndube FA; Hasenfuss G; Belardinelli L; Maier LS
J Am Coll Cardiol; 2010 May; 55(21):2330-42. PubMed ID: 20488304
[TBL] [Abstract][Full Text] [Related]
20. Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes.
Wang Z; Fermini B; Nattel S
J Pharmacol Exp Ther; 1995 Jan; 272(1):184-96. PubMed ID: 7815332
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]