These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 23369253)

  • 1. Characterization of the novel Trypanosoma brucei inosine 5'-monophosphate dehydrogenase.
    Bessho T; Morii S; Kusumoto T; Shinohara T; Noda M; Uchiyama S; Shuto S; Nishimura S; Djikeng A; Duszenko M; Martin SK; Inui T; Kubata KB
    Parasitology; 2013 May; 140(6):735-45. PubMed ID: 23369253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid.
    Digits JA; Hedstrom L
    Biochemistry; 1999 Nov; 38(46):15388-97. PubMed ID: 10563825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
    Dobie F; Berg A; Boitz JM; Jardim A
    Mol Biochem Parasitol; 2007 Mar; 152(1):11-21. PubMed ID: 17173987
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.
    Hager PW; Collart FR; Huberman E; Mitchell BS
    Biochem Pharmacol; 1995 May; 49(9):1323-9. PubMed ID: 7763314
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Monovalent cation activation in Escherichia coli inosine 5'-monophosphate dehydrogenase.
    Kerr KM; Cahoon M; Bosco DA; Hedstrom L
    Arch Biochem Biophys; 2000 Mar; 375(1):131-7. PubMed ID: 10683258
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Prosise GL; Luecke H
    J Mol Biol; 2003 Feb; 326(2):517-27. PubMed ID: 12559919
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acid-base catalysis in the chemical mechanism of inosine monophosphate dehydrogenase.
    Markham GD; Bock CL; Schalk-Hihi C
    Biochemistry; 1999 Apr; 38(14):4433-40. PubMed ID: 10194364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.
    Gan L; Petsko GA; Hedstrom L
    Biochemistry; 2002 Nov; 41(44):13309-17. PubMed ID: 12403633
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.
    Pankiewicz KW; Patterson SE; Black PL; Jayaram HN; Risal D; Goldstein BM; Stuyver LJ; Schinazi RF
    Curr Med Chem; 2004 Apr; 11(7):887-900. PubMed ID: 15083807
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors.
    Nass K; Redecke L; Perbandt M; Yefanov O; Klinge M; Koopmann R; Stellato F; Gabdulkhakov A; Schönherr R; Rehders D; Lahey-Rudolph JM; Aquila A; Barty A; Basu S; Doak RB; Duden R; Frank M; Fromme R; Kassemeyer S; Katona G; Kirian R; Liu H; Majoul I; Martin-Garcia JM; Messerschmidt M; Shoeman RL; Weierstall U; Westenhoff S; White TA; Williams GJ; Yoon CH; Zatsepin N; Fromme P; Duszenko M; Chapman HN; Betzel C
    Nat Commun; 2020 Jan; 11(1):620. PubMed ID: 32001697
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of Tritrichomonas foetus inosine monophosphate dehydrogenase in complex with the inhibitor ribavirin monophosphate reveals a catalysis-dependent ion-binding site.
    Prosise GL; Wu JZ; Luecke H
    J Biol Chem; 2002 Dec; 277(52):50654-9. PubMed ID: 12235158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery.
    Shu Q; Nair V
    Med Res Rev; 2008 Mar; 28(2):219-32. PubMed ID: 17480004
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel Characteristics of Trypanosoma brucei Guanosine 5'-monophosphate Reductase Distinct from Host Animals.
    Bessho T; Okada T; Kimura C; Shinohara T; Tomiyama A; Imamura A; Kuwamura M; Nishimura K; Fujimori K; Shuto S; Ishibashi O; Kubata BK; Inui T
    PLoS Negl Trop Dis; 2016 Jan; 10(1):e0004339. PubMed ID: 26731263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
    Makowska-Grzyska M; Kim Y; Wu R; Wilton R; Gollapalli DR; Wang XK; Zhang R; Jedrzejczak R; Mack JC; Maltseva N; Mulligan R; Binkowski TA; Gornicki P; Kuhn ML; Anderson WF; Hedstrom L; Joachimiak A
    Biochemistry; 2012 Aug; 51(31):6148-63. PubMed ID: 22788966
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate.
    Wang W; Papov VV; Minakawa N; Matsuda A; Biemann K; Hedstrom L
    Biochemistry; 1996 Jan; 35(1):95-101. PubMed ID: 8555204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation and characterization of mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase.
    Farazi T; Leichman J; Harris T; Cahoon M; Hedstrom L
    J Biol Chem; 1997 Jan; 272(2):961-5. PubMed ID: 8995388
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.
    Fleming MA; Chambers SP; Connelly PR; Nimmesgern E; Fox T; Bruzzese FJ; Hoe ST; Fulghum JR; Livingston DJ; Stuver CM; Sintchak MD; Wilson KP; Thomson JA
    Biochemistry; 1996 Jun; 35(22):6990-7. PubMed ID: 8679523
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
    McMillan FM; Cahoon M; White A; Hedstrom L; Petsko GA; Ringe D
    Biochemistry; 2000 Apr; 39(15):4533-42. PubMed ID: 10758003
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cloning, characterization and validation of inosine 5'-monophosphate dehydrogenase of Babesia gibsoni as molecular drug target.
    Cao S; Aboge GO; Terkawi MA; Zhou M; Luo Y; Yu L; Li Y; Goo Y; Kamyingkird K; Masatani T; Suzuki H; Igarashi I; Nishikawa Y; Xuan X
    Parasitol Int; 2013 Apr; 62(2):87-94. PubMed ID: 23142571
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
    Hedstrom L; Wang CC
    Biochemistry; 1990 Jan; 29(4):849-54. PubMed ID: 1971185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.