BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 23373462)

  • 1. Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase.
    Burgos ES; Vetticatt MJ; Schramm VL
    J Am Chem Soc; 2013 Mar; 135(9):3485-93. PubMed ID: 23373462
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase.
    Takahashi R; Nakamura S; Nakazawa T; Minoura K; Yoshida T; Nishi Y; Kobayashi Y; Ohkubo T
    J Biochem; 2010 Jan; 147(1):95-107. PubMed ID: 19819904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD
    Grolla AA; Miggiano R; Di Marino D; Bianchi M; Gori A; Orsomando G; Gaudino F; Galli U; Del Grosso E; Mazzola F; Angeletti C; Guarneri M; Torretta S; Calabrò M; Boumya S; Fan X; Colombo G; Travelli C; Rocchio F; Aronica E; Wohlschlegel JA; Deaglio S; Rizzi M; Genazzani AA; Garavaglia S
    J Biol Chem; 2020 Mar; 295(11):3635-3651. PubMed ID: 31988240
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma.
    Hara N; Yamada K; Shibata T; Osago H; Tsuchiya M
    PLoS One; 2011; 6(8):e22781. PubMed ID: 21826208
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
    Burgos ES; Ho MC; Almo SC; Schramm VL
    Proc Natl Acad Sci U S A; 2009 Aug; 106(33):13748-53. PubMed ID: 19666527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase.
    Burgos ES; Schramm VL
    Biochemistry; 2008 Oct; 47(42):11086-96. PubMed ID: 18823127
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NAMPT in regulated NAD biosynthesis and its pivotal role in human metabolism.
    Burgos ES
    Curr Med Chem; 2011; 18(13):1947-61. PubMed ID: 21517777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into Xanthomonas campestris pv. campestris NAD
    Xu G; Ma J; Fang Q; Peng Q; Jiao X; Hu W; Zhao Q; Kong Y; Liu F; Shi X; Tang DJ; Tang JL; Ming Z
    Commun Biol; 2024 Mar; 7(1):255. PubMed ID: 38429435
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.
    Zhang Y; Schramm VL
    J Am Chem Soc; 2010 Jun; 132(25):8787-94. PubMed ID: 20527751
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity.
    Houry D; Raasakka A; Ferrario E; Niere M; Bifulco E; Kursula P; Ziegler M
    J Struct Biol; 2023 Sep; 215(3):108004. PubMed ID: 37495196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic isotope effect characterization of the transition state for oxidized nicotinamide adenine dinucleotide hydrolysis by pertussis toxin.
    Scheuring J; Schramm VL
    Biochemistry; 1997 Apr; 36(15):4526-34. PubMed ID: 9109661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of evolutionary and kinetic drivers of NAD-dependent signaling.
    Bockwoldt M; Houry D; Niere M; Gossmann TI; Reinartz I; Schug A; Ziegler M; Heiland I
    Proc Natl Acad Sci U S A; 2019 Aug; 116(32):15957-15966. PubMed ID: 31341085
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transition state structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli and its similarity to transition state analogues.
    Singh V; Lee JE; Núñez S; Howell PL; Schramm VL
    Biochemistry; 2005 Sep; 44(35):11647-59. PubMed ID: 16128565
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin.
    Parikh SL; Schramm VL
    Biochemistry; 2004 Feb; 43(5):1204-12. PubMed ID: 14756556
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improvement of an enzymatic cascade synthesis of nicotinamide mononucleotide via protein engineering and reaction-process reinforcement.
    Peng F; Hong J; Cui J; An YN; Guo Q; Shen Q; Cheng F; Xue YP; Zheng YG
    Biotechnol J; 2024 Feb; 19(2):e2300748. PubMed ID: 38403401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD
    Ratia KM; Shen Z; Gordon-Blake J; Lee H; Laham MS; Krider IS; Christie N; Ackerman-Berrier M; Penton C; Knowles NG; Musku SR; Fu J; Velma GR; Xiong R; Thatcher GRJ
    Biochemistry; 2023 Feb; 62(4):923-933. PubMed ID: 36746631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening.
    Ozgencil F; Eren G; Ozkan Y; Guntekin-Ergun S; Cetin-Atalay R
    Bioorg Med Chem; 2020 Jan; 28(1):115217. PubMed ID: 31818629
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity.
    Ugamraj HS; Dang K; Ouisse LH; Buelow B; Chini EN; Castello G; Allison J; Clarke SC; Davison LM; Buelow R; Deng R; Iyer S; Schellenberger U; Manika SN; Bijpuria S; Musnier A; Poupon A; Cuturi MC; van Schooten W; Dalvi P
    MAbs; 2022; 14(1):2095949. PubMed ID: 35867844
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ground-state destabilization in orotate phosphoribosyltransferases by binding isotope effects.
    Zhang Y; Schramm VL
    Biochemistry; 2011 May; 50(21):4813-8. PubMed ID: 21526795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
    Shen Z; Ratia K; Krider I; Ackerman-Berrier M; Penton C; Musku SR; Gordon-Blake JM; Laham MS; Christie N; Ma N; Fu J; Xiong R; Courey JM; Velma GR; Thatcher GRJ
    J Med Chem; 2023 Dec; 66(24):16704-16727. PubMed ID: 38096366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.