BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

592 related articles for article (PubMed ID: 23374347)

  • 1. Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.
    Czabotar PE; Westphal D; Dewson G; Ma S; Hockings C; Fairlie WD; Lee EF; Yao S; Robin AY; Smith BJ; Huang DC; Kluck RM; Adams JM; Colman PM
    Cell; 2013 Jan; 152(3):519-31. PubMed ID: 23374347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL.
    Parikh N; Koshy C; Dhayabaran V; Perumalsamy LR; Sowdhamini R; Sarin A
    BMC Cell Biol; 2007 May; 8():16. PubMed ID: 17519046
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
    Robin AY; Krishna Kumar K; Westphal D; Wardak AZ; Thompson GV; Dewson G; Colman PM; Czabotar PE
    Cell Death Dis; 2015 Jul; 6(7):e1809. PubMed ID: 26158515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bax dimerizes via a symmetric BH3:groove interface during apoptosis.
    Dewson G; Ma S; Frederick P; Hockings C; Tan I; Kratina T; Kluck RM
    Cell Death Differ; 2012 Apr; 19(4):661-70. PubMed ID: 22015607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.
    Brouwer JM; Westphal D; Dewson G; Robin AY; Uren RT; Bartolo R; Thompson GV; Colman PM; Kluck RM; Czabotar PE
    Mol Cell; 2014 Sep; 55(6):938-946. PubMed ID: 25175025
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove.
    Li MX; Tan IKL; Ma SB; Hockings C; Kratina T; Dengler MA; Alsop AE; Kluck RM; Dewson G
    Proc Natl Acad Sci U S A; 2017 Jul; 114(29):7629-7634. PubMed ID: 28673969
    [TBL] [Abstract][Full Text] [Related]  

  • 7. To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.
    Dewson G; Kratina T; Sim HW; Puthalakath H; Adams JM; Colman PM; Kluck RM
    Mol Cell; 2008 May; 30(3):369-80. PubMed ID: 18471982
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Organization of the mitochondrial apoptotic BAK pore: oligomerization of the BAK homodimers.
    Aluvila S; Mandal T; Hustedt E; Fajer P; Choe JY; Oh KJ
    J Biol Chem; 2014 Jan; 289(5):2537-51. PubMed ID: 24337568
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bax activation and mitochondrial insertion during apoptosis.
    Lalier L; Cartron PF; Juin P; Nedelkina S; Manon S; Bechinger B; Vallette FM
    Apoptosis; 2007 May; 12(5):887-96. PubMed ID: 17453158
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis.
    Annis MG; Soucie EL; Dlugosz PJ; Cruz-Aguado JA; Penn LZ; Leber B; Andrews DW
    EMBO J; 2005 Jun; 24(12):2096-103. PubMed ID: 15920484
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
    Kvansakul M; Yang H; Fairlie WD; Czabotar PE; Fischer SF; Perugini MA; Huang DC; Colman PM
    Cell Death Differ; 2008 Oct; 15(10):1564-71. PubMed ID: 18551131
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
    Cancer Res; 2003 Apr; 63(7):1712-21. PubMed ID: 12670926
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA.
    Pauleau AL; Larochette N; Giordanetto F; Scholz SR; Poncet D; Zamzami N; Goldmacher VS; Kroemer G
    Oncogene; 2007 Nov; 26(50):7067-80. PubMed ID: 17496930
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.
    Roucou X; Montessuit S; Antonsson B; Martinou JC
    Biochem J; 2002 Dec; 368(Pt 3):915-21. PubMed ID: 12193163
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions.
    Finnegan NM; Curtin JF; Prevost G; Morgan B; Cotter TG
    Br J Cancer; 2001 Jul; 85(1):115-21. PubMed ID: 11437412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association.
    Dengler MA; Robin AY; Gibson L; Li MX; Sandow JJ; Iyer S; Webb AI; Westphal D; Dewson G; Adams JM
    Cell Rep; 2019 Apr; 27(2):359-373.e6. PubMed ID: 30970242
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
    Chipuk JE; Kuwana T; Bouchier-Hayes L; Droin NM; Newmeyer DD; Schuler M; Green DR
    Science; 2004 Feb; 303(5660):1010-4. PubMed ID: 14963330
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BH3-only proteins trigger cytochrome c release, but how?
    Häcker G; Weber A
    Arch Biochem Biophys; 2007 Jun; 462(2):150-5. PubMed ID: 17306210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells.
    Naresh A; Long W; Vidal GA; Wimley WC; Marrero L; Sartor CI; Tovey S; Cooke TG; Bartlett JM; Jones FE
    Cancer Res; 2006 Jun; 66(12):6412-20. PubMed ID: 16778220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices.
    Dewson G; Kratina T; Czabotar P; Day CL; Adams JM; Kluck RM
    Mol Cell; 2009 Nov; 36(4):696-703. PubMed ID: 19941828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.