841 related articles for article (PubMed ID: 23374348)
1. The dynamic process of β(2)-adrenergic receptor activation.
Nygaard R; Zou Y; Dror RO; Mildorf TJ; Arlow DH; Manglik A; Pan AC; Liu CW; Fung JJ; Bokoch MP; Thian FS; Kobilka TS; Shaw DE; Mueller L; Prosser RS; Kobilka BK
Cell; 2013 Jan; 152(3):532-42. PubMed ID: 23374348
[TBL] [Abstract][Full Text] [Related]
2. Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes.
Isin B; Estiu G; Wiest O; Oltvai ZN
PLoS One; 2012; 7(12):e50186. PubMed ID: 23300522
[TBL] [Abstract][Full Text] [Related]
3. Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators.
Reynolds KA; Katritch V; Abagyan R
J Comput Aided Mol Des; 2009 May; 23(5):273-88. PubMed ID: 19148767
[TBL] [Abstract][Full Text] [Related]
4. Insight into partial agonism by observing multiple equilibria for ligand-bound and G
Solt AS; Bostock MJ; Shrestha B; Kumar P; Warne T; Tate CG; Nietlispach D
Nat Commun; 2017 Nov; 8(1):1795. PubMed ID: 29176642
[TBL] [Abstract][Full Text] [Related]
5. Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling.
Manglik A; Kim TH; Masureel M; Altenbach C; Yang Z; Hilger D; Lerch MT; Kobilka TS; Thian FS; Hubbell WL; Prosser RS; Kobilka BK
Cell; 2015 May; 161(5):1101-1111. PubMed ID: 25981665
[TBL] [Abstract][Full Text] [Related]
6. Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
Staus DP; Strachan RT; Manglik A; Pani B; Kahsai AW; Kim TH; Wingler LM; Ahn S; Chatterjee A; Masoudi A; Kruse AC; Pardon E; Steyaert J; Weis WI; Prosser RS; Kobilka BK; Costa T; Lefkowitz RJ
Nature; 2016 Jul; 535(7612):448-52. PubMed ID: 27409812
[TBL] [Abstract][Full Text] [Related]
7. Efficacy of the β₂-adrenergic receptor is determined by conformational equilibrium in the transmembrane region.
Kofuku Y; Ueda T; Okude J; Shiraishi Y; Kondo K; Maeda M; Tsujishita H; Shimada I
Nat Commun; 2012; 3():1045. PubMed ID: 22948827
[TBL] [Abstract][Full Text] [Related]
8. Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
Rosenbaum DM; Zhang C; Lyons JA; Holl R; Aragao D; Arlow DH; Rasmussen SG; Choi HJ; Devree BT; Sunahara RK; Chae PS; Gellman SH; Dror RO; Shaw DE; Weis WI; Caffrey M; Gmeiner P; Kobilka BK
Nature; 2011 Jan; 469(7329):236-40. PubMed ID: 21228876
[TBL] [Abstract][Full Text] [Related]
9. Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study.
Kooistra AJ; Leurs R; de Esch IJ; de Graaf C
J Chem Inf Model; 2015 May; 55(5):1045-61. PubMed ID: 25848966
[TBL] [Abstract][Full Text] [Related]
10. Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.
DeVree BT; Mahoney JP; Vélez-Ruiz GA; Rasmussen SG; Kuszak AJ; Edwald E; Fung JJ; Manglik A; Masureel M; Du Y; Matt RA; Pardon E; Steyaert J; Kobilka BK; Sunahara RK
Nature; 2016 Jul; 535(7610):182-6. PubMed ID: 27362234
[TBL] [Abstract][Full Text] [Related]
11. Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Bokoch MP; Zou Y; Rasmussen SG; Liu CW; Nygaard R; Rosenbaum DM; Fung JJ; Choi HJ; Thian FS; Kobilka TS; Puglisi JD; Weis WI; Pardo L; Prosser RS; Mueller L; Kobilka BK
Nature; 2010 Jan; 463(7277):108-12. PubMed ID: 20054398
[TBL] [Abstract][Full Text] [Related]
12. Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics.
Tikhonova IG; Selvam B; Ivetac A; Wereszczynski J; McCammon JA
Biochemistry; 2013 Aug; 52(33):5593-603. PubMed ID: 23879802
[TBL] [Abstract][Full Text] [Related]
13. Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.
Liu JJ; Horst R; Katritch V; Stevens RC; Wüthrich K
Science; 2012 Mar; 335(6072):1106-10. PubMed ID: 22267580
[TBL] [Abstract][Full Text] [Related]
14. Ligand-stabilized conformational states of human beta(2) adrenergic receptor: insight into G-protein-coupled receptor activation.
Bhattacharya S; Hall SE; Li H; Vaidehi N
Biophys J; 2008 Mar; 94(6):2027-42. PubMed ID: 18065472
[TBL] [Abstract][Full Text] [Related]
15. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
Huber T; Menon S; Sakmar TP
Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
[TBL] [Abstract][Full Text] [Related]
16. Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches.
Fleetwood O; Matricon P; Carlsson J; Delemotte L
Biochemistry; 2020 Feb; 59(7):880-891. PubMed ID: 31999436
[TBL] [Abstract][Full Text] [Related]
17. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
Bhattacharya S; Hall SE; Vaidehi N
J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
[TBL] [Abstract][Full Text] [Related]
18. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
Rasmussen SG; Choi HJ; Fung JJ; Pardon E; Casarosa P; Chae PS; Devree BT; Rosenbaum DM; Thian FS; Kobilka TS; Schnapp A; Konetzki I; Sunahara RK; Gellman SH; Pautsch A; Steyaert J; Weis WI; Kobilka BK
Nature; 2011 Jan; 469(7329):175-80. PubMed ID: 21228869
[TBL] [Abstract][Full Text] [Related]
19. Structural features of β2 adrenergic receptor: crystal structures and beyond.
Bang I; Choi HJ
Mol Cells; 2015; 38(2):105-11. PubMed ID: 25537861
[TBL] [Abstract][Full Text] [Related]
20. Structure-based simulations reveal concerted dynamics of GPCR activation.
Leioatts N; Suresh P; Romo TD; Grossfield A
Proteins; 2014 Oct; 82(10):2538-51. PubMed ID: 24889093
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]