404 related articles for article (PubMed ID: 23382044)
21. SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Lee DH; Park JS; Lee YS; Han J; Lee DK; Kwon SW; Han DH; Lee YH; Bae SH
Autophagy; 2020 Nov; 16(11):1949-1973. PubMed ID: 31913745
[TBL] [Abstract][Full Text] [Related]
22. Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.
Shibata T; Ohta T; Tong KI; Kokubu A; Odogawa R; Tsuta K; Asamura H; Yamamoto M; Hirohashi S
Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13568-73. PubMed ID: 18757741
[TBL] [Abstract][Full Text] [Related]
23. Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein.
Camp ND; James RG; Dawson DW; Yan F; Davison JM; Houck SA; Tang X; Zheng N; Major MB; Moon RT
J Biol Chem; 2012 Feb; 287(9):6539-50. PubMed ID: 22215675
[TBL] [Abstract][Full Text] [Related]
24. Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma.
Knatko EV; Higgins M; Fahey JW; Dinkova-Kostova AT
Sci Rep; 2016 May; 6():25804. PubMed ID: 27216826
[TBL] [Abstract][Full Text] [Related]
25. Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1.
Fukutomi T; Takagi K; Mizushima T; Ohuchi N; Yamamoto M
Mol Cell Biol; 2014 Mar; 34(5):832-46. PubMed ID: 24366543
[TBL] [Abstract][Full Text] [Related]
26. Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Toyama T; Sumi D; Shinkai Y; Yasutake A; Taguchi K; Tong KI; Yamamoto M; Kumagai Y
Biochem Biophys Res Commun; 2007 Nov; 363(3):645-50. PubMed ID: 17904103
[TBL] [Abstract][Full Text] [Related]
27. CDK20 interacts with KEAP1 to activate NRF2 and promotes radiochemoresistance in lung cancer cells.
Wang Q; Ma J; Lu Y; Zhang S; Huang J; Chen J; Bei JX; Yang K; Wu G; Huang K; Chen J; Xu S
Oncogene; 2017 Sep; 36(37):5321-5330. PubMed ID: 28534518
[TBL] [Abstract][Full Text] [Related]
28. An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes.
Liu Z; Deng M; Wu L; Zhang S
Mol Med; 2020 May; 26(1):48. PubMed ID: 32434476
[TBL] [Abstract][Full Text] [Related]
29. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
Furukawa M; Xiong Y
Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
[TBL] [Abstract][Full Text] [Related]
30. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.
Zhang DD; Lo SC; Sun Z; Habib GM; Lieberman MW; Hannink M
J Biol Chem; 2005 Aug; 280(34):30091-9. PubMed ID: 15983046
[TBL] [Abstract][Full Text] [Related]
31. Loss-of-function mutations in KEAP1 drive lung cancer progression via KEAP1/NRF2 pathway activation.
Gong M; Li Y; Ye X; Zhang L; Wang Z; Xu X; Shen Y; Zheng C
Cell Commun Signal; 2020 Jun; 18(1):98. PubMed ID: 32576270
[TBL] [Abstract][Full Text] [Related]
32. Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
Padmanabhan B; Tong KI; Ohta T; Nakamura Y; Scharlock M; Ohtsuji M; Kang MI; Kobayashi A; Yokoyama S; Yamamoto M
Mol Cell; 2006 Mar; 21(5):689-700. PubMed ID: 16507366
[TBL] [Abstract][Full Text] [Related]
33. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress.
Zhang DD; Hannink M
Mol Cell Biol; 2003 Nov; 23(22):8137-51. PubMed ID: 14585973
[TBL] [Abstract][Full Text] [Related]
34. Canonical and non-canonical mechanisms of Nrf2 activation.
Silva-Islas CA; Maldonado PD
Pharmacol Res; 2018 Aug; 134():92-99. PubMed ID: 29913224
[TBL] [Abstract][Full Text] [Related]
35. Acute expression of the transcription factor Nrf2 after treatment with quinolinic acid is not induced by oxidative stress in the rat striatum.
Silva-Islas CA; Chánez-Cárdenas ME; Barrera-Oviedo D; Ibarra-Rubio ME; Maldonado PD
Neurotoxicology; 2019 Jul; 73():120-131. PubMed ID: 30876764
[TBL] [Abstract][Full Text] [Related]
36. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.
Lau A; Wang XJ; Zhao F; Villeneuve NF; Wu T; Jiang T; Sun Z; White E; Zhang DD
Mol Cell Biol; 2010 Jul; 30(13):3275-85. PubMed ID: 20421418
[TBL] [Abstract][Full Text] [Related]
37. Sp1 is a substrate of Keap1 and regulates the activity of CRL4A
Siswanto FM; Oguro A; Imaoka S
J Biol Chem; 2021; 296():100704. PubMed ID: 33895141
[TBL] [Abstract][Full Text] [Related]
38. Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex.
Baird L; Llères D; Swift S; Dinkova-Kostova AT
Proc Natl Acad Sci U S A; 2013 Sep; 110(38):15259-64. PubMed ID: 23986495
[TBL] [Abstract][Full Text] [Related]
39. Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process.
Matić S; Kekez I; Tomin M; Bogár F; Šupljika F; Kazazić S; Hanić M; Jha S; Brkić H; Bourgeois B; Madl T; Gruber K; Macheroux P; Matković-Čalogović D; Matovina M; Tomić S
J Biomol Struct Dyn; 2021 Nov; 39(18):6870-6881. PubMed ID: 32811353
[TBL] [Abstract][Full Text] [Related]
40. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases.
Villeneuve NF; Lau A; Zhang DD
Antioxid Redox Signal; 2010 Dec; 13(11):1699-712. PubMed ID: 20486766
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]