BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 23382194)

  • 21. Angiotensin II up-regulates the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF), a regulator of G protein signaling domain-containing RhoGEF, in vascular smooth muscle cells.
    Ying Z; Jin L; Palmer T; Webb RC
    Mol Pharmacol; 2006 Mar; 69(3):932-40. PubMed ID: 16354763
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identification of the first Rho-GEF inhibitor, TRIPalpha, which targets the RhoA-specific GEF domain of Trio.
    Schmidt S; Diriong S; Méry J; Fabbrizio E; Debant A
    FEBS Lett; 2002 Jul; 523(1-3):35-42. PubMed ID: 12123800
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Recognition and activation of Rho GTPases by Vav1 and Vav2 guanine nucleotide exchange factors.
    Heo J; Thapar R; Campbell SL
    Biochemistry; 2005 May; 44(17):6573-85. PubMed ID: 15850391
    [TBL] [Abstract][Full Text] [Related]  

  • 24. LARG links histamine-H1-receptor-activated Gq to Rho-GTPase-dependent signaling pathways.
    Pfreimer M; Vatter P; Langer T; Wieland T; Gierschik P; Moepps B
    Cell Signal; 2012 Mar; 24(3):652-63. PubMed ID: 22100544
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hyaluronan-CD44 interaction with leukemia-associated RhoGEF and epidermal growth factor receptor promotes Rho/Ras co-activation, phospholipase C epsilon-Ca2+ signaling, and cytoskeleton modification in head and neck squamous cell carcinoma cells.
    Bourguignon LY; Gilad E; Brightman A; Diedrich F; Singleton P
    J Biol Chem; 2006 May; 281(20):14026-40. PubMed ID: 16565089
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural insights into the activation of the RhoA GTPase by the lymphoid blast crisis (Lbc) oncoprotein.
    Lenoir M; Sugawara M; Kaur J; Ball LJ; Overduin M
    J Biol Chem; 2014 Aug; 289(34):23992-4004. PubMed ID: 24993829
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
    Wang L; Zhu K; Zheng Y
    Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.
    Perrot V; Vazquez-Prado J; Gutkind JS
    J Biol Chem; 2002 Nov; 277(45):43115-20. PubMed ID: 12183458
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Targeting the Dbl and dock-family RhoGEFs: a yeast-based assay to identify cell-active inhibitors of Rho-controlled pathways.
    Blangy A; Fort P
    Enzymes; 2013; 33 Pt A():169-91. PubMed ID: 25033805
    [TBL] [Abstract][Full Text] [Related]  

  • 30. CYLD regulates RhoA activity by modulating LARG ubiquitination.
    Yang Y; Sun L; Tala ; Gao J; Li D; Zhou J; Liu M
    PLoS One; 2013; 8(2):e55833. PubMed ID: 23405219
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.
    Bielnicki JA; Shkumatov AV; Derewenda U; Somlyo AV; Svergun DI; Derewenda ZS
    J Biol Chem; 2011 Oct; 286(40):35163-75. PubMed ID: 21816819
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases.
    Shang X; Marchioni F; Sipes N; Evelyn CR; Jerabek-Willemsen M; Duhr S; Seibel W; Wortman M; Zheng Y
    Chem Biol; 2012 Jun; 19(6):699-710. PubMed ID: 22726684
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs).
    Yamada T; Ohoka Y; Kogo M; Inagaki S
    J Biol Chem; 2005 May; 280(19):19358-63. PubMed ID: 15755723
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion.
    Kitzing TM; Sahadevan AS; Brandt DT; Knieling H; Hannemann S; Fackler OT; Grosshans J; Grosse R
    Genes Dev; 2007 Jun; 21(12):1478-83. PubMed ID: 17575049
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface.
    Suzuki N; Tsumoto K; Hajicek N; Daigo K; Tokita R; Minami S; Kodama T; Hamakubo T; Kozasa T
    J Biol Chem; 2009 Feb; 284(8):5000-9. PubMed ID: 19074425
    [TBL] [Abstract][Full Text] [Related]  

  • 36. [Role of the multifunctional Trio protein in the control of the Rac1 and RhoA gtpase signaling pathways].
    Bellanger JM; Zugasti O; Lazaro JB; Diriong S; Lamb N; Sardet C; Debant A
    C R Seances Soc Biol Fil; 1998; 192(2):367-74. PubMed ID: 9759378
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Oligomerization of DH domain is essential for Dbl-induced transformation.
    Zhu K; Debreceni B; Bi F; Zheng Y
    Mol Cell Biol; 2001 Jan; 21(2):425-37. PubMed ID: 11134331
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation--molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor.
    Higashibata A; Imamizo-Sato M; Seki M; Yamazaki T; Ishioka N
    BMC Biochem; 2006 Jun; 7():19. PubMed ID: 16803636
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.
    Williams CM; Harper MT; Goggs R; Walsh TG; Offermanns S; Poole AW
    J Thromb Haemost; 2015 Nov; 13(11):2102-7. PubMed ID: 26334261
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho.
    Fukuhara S; Chikumi H; Gutkind JS
    FEBS Lett; 2000 Nov; 485(2-3):183-8. PubMed ID: 11094164
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.