153 related articles for article (PubMed ID: 2338648)
1. Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: roles of glutathione.
Thomassen D; Slattery JT; Nelson SD
J Pharmacol Exp Ther; 1990 May; 253(2):567-72. PubMed ID: 2338648
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.
Khojasteh-Bakht SC; Chen W; Koenigs LL; Peter RM; Nelson SD
Drug Metab Dispos; 1999 May; 27(5):574-80. PubMed ID: 10220485
[TBL] [Abstract][Full Text] [Related]
3. The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran.
Gordon WP; Huitric AC; Seth CL; McClanahan RH; Nelson SD
Drug Metab Dispos; 1987; 15(5):589-94. PubMed ID: 2891472
[TBL] [Abstract][Full Text] [Related]
4. Contribution of menthofuran to the hepatotoxicity of pulegone: assessment based on matched area under the curve and on matched time course.
Thomassen D; Slattery JT; Nelson SD
J Pharmacol Exp Ther; 1988 Mar; 244(3):825-9. PubMed ID: 3252034
[TBL] [Abstract][Full Text] [Related]
5. Partial characterization of biliary metabolites of pulegone by tandem mass spectrometry. Detection of glucuronide, glutathione, and glutathionyl glucuronide conjugates.
Thomassen D; Pearson PG; Slattery JT; Nelson SD
Drug Metab Dispos; 1991; 19(5):997-1003. PubMed ID: 1686249
[TBL] [Abstract][Full Text] [Related]
6. Effects of drug metabolism modifiers on pulegone-induced hepatotoxicity in mice.
Mizutani T; Nomura H; Nakanishi K; Fujita S
Res Commun Chem Pathol Pharmacol; 1987 Oct; 58(1):75-83. PubMed ID: 3432735
[TBL] [Abstract][Full Text] [Related]
7. Metabolism of (R)-(+)-pulegone in F344 rats.
Chen LJ; Lebetkin EH; Burka LT
Drug Metab Dispos; 2001 Dec; 29(12):1567-77. PubMed ID: 11717176
[TBL] [Abstract][Full Text] [Related]
8. Investigations of mechanisms of reactive metabolite formation from (R)-(+)-pulegone.
Nelson SD; McClanahan RH; Thomassen D; Gordon WP; Knebel N
Xenobiotica; 1992; 22(9-10):1157-64. PubMed ID: 1441606
[TBL] [Abstract][Full Text] [Related]
9. Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones.
Khojasteh-Bakht SC; Nelson SD; Atkins WM
Arch Biochem Biophys; 1999 Oct; 370(1):59-65. PubMed ID: 10496977
[TBL] [Abstract][Full Text] [Related]
10. Enhancement of cisplatin toxicity by buthionine sulfoximine, a glutathione-depleting agent, in mice.
Ishikawa M; Takayanagi Y; Sasaki K
Res Commun Chem Pathol Pharmacol; 1990 Jan; 67(1):131-41. PubMed ID: 2326543
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites.
Chen LJ; Lebetkin EH; Burka LT
Drug Metab Dispos; 2003 Oct; 31(10):1208-13. PubMed ID: 12975329
[TBL] [Abstract][Full Text] [Related]
12. Role of C-5 chiral center in R-(+)-pulegone-mediated hepatotoxicity: metabolic disposition and toxicity of 5, 5-dimethyl-2-(1-Methylethylidene)-cyclohexanone in rats.
Thulasiram HV; Gadad AK; Madyastha MK
Drug Metab Dispos; 2000 Jul; 28(7):833-44. PubMed ID: 10859158
[TBL] [Abstract][Full Text] [Related]
13. Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature.
Anderson IB; Mullen WH; Meeker JE; Khojasteh-BakhtSC ; Oishi S; Nelson SD; Blanc PD
Ann Intern Med; 1996 Apr; 124(8):726-34. PubMed ID: 8633832
[TBL] [Abstract][Full Text] [Related]
14. Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene.
Bertea CM; Schalk M; Karp F; Maffei M; Croteau R
Arch Biochem Biophys; 2001 Jun; 390(2):279-86. PubMed ID: 11396930
[TBL] [Abstract][Full Text] [Related]
15. Final report on the safety assessment of Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, and Mentha Piperita (Peppermint) Leaf Water.
Nair B
Int J Toxicol; 2001; 20 Suppl 3():61-73. PubMed ID: 11766133
[TBL] [Abstract][Full Text] [Related]
16. Changes in rat liver gene expression induced by thioacetamide: protective role of S-adenosyl-L-methionine by a glutathione-dependent mechanism.
Mesa ML; Carrizosa R; MartÃnez-Honduvilla C; Benito M; Fabregat I
Hepatology; 1996 Mar; 23(3):600-6. PubMed ID: 8617442
[TBL] [Abstract][Full Text] [Related]
17. Pulegone mediated hepatotoxicity: evidence for covalent binding of R(+)-[14C]pulegone to microsomal proteins in vitro.
Madyastha KM; Moorthy B
Chem Biol Interact; 1989; 72(3):325-33. PubMed ID: 2691105
[TBL] [Abstract][Full Text] [Related]
18. 14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats.
Ferguson LJ; Lebetkin EH; Lih FB; Tomer KB; Parkinson HD; Borghoff SJ; Burka LT
J Toxicol Environ Health A; 2007 Sep; 70(17):1416-23. PubMed ID: 17687727
[TBL] [Abstract][Full Text] [Related]
19. Role of glutathione in cyclosporine A in vitro hepatotoxicity.
Wolf A; Trendelenburg CF; Diez-Fernandez C; Prieto P; Cordier A
Transplant Proc; 1994 Oct; 26(5):2912-4. PubMed ID: 7940920
[No Abstract] [Full Text] [Related]
20. Hepatotoxicity of pulegone in rats: its effects on microsomal enzymes, in vivo.
Moorthy B; Madyastha P; Madyastha KM
Toxicology; 1989 May; 55(3):327-37. PubMed ID: 2541521
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
