BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 23391575)

  • 1. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
    Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
    Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
    Kaina B; Christmann M; Naumann S; Roos WP
    DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
    Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
    DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PARP1-MGMT complex underpins pathway crosstalk in O
    Cropper JD; Alimbetov DS; Brown KTG; Likhotvorik RI; Robles AJ; Guerra JT; He B; Chen Y; Kwon Y; Kurmasheva RT
    J Hematol Oncol; 2022 Oct; 15(1):146. PubMed ID: 36242092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
    Roos W; Baumgartner M; Kaina B
    Oncogene; 2004 Jan; 23(2):359-67. PubMed ID: 14724564
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
    Göder A; Nagel G; Kraus A; Dörsam B; Seiwert N; Kaina B; Fahrer J
    Carcinogenesis; 2015 Aug; 36(8):817-31. PubMed ID: 25998848
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repair of O(6)-methylguanine is not affected by thymine base pairing and the presence of MMR proteins.
    Lips J; Kaina B
    Mutat Res; 2001 Nov; 487(1-2):59-66. PubMed ID: 11595409
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O
    Kraus A; McKeague M; Seiwert N; Nagel G; Geisen SM; Ziegler N; Trantakis IA; Kaina B; Thomas AD; Sturla SJ; Fahrer J
    Arch Toxicol; 2019 Feb; 93(2):559-572. PubMed ID: 30446773
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.
    Hashimoto K; Sharma V; Sasanuma H; Tian X; Takata M; Takeda S; Swenberg JA; Nakamura J
    Oncotarget; 2016 Sep; 7(37):59795-59808. PubMed ID: 27486975
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triazene compounds: mechanism of action and related DNA repair systems.
    Marchesi F; Turriziani M; Tortorelli G; Avvisati G; Torino F; De Vecchis L
    Pharmacol Res; 2007 Oct; 56(4):275-87. PubMed ID: 17897837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Methylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNP.
    Kristensen LS; Nielsen HM; Hager H; Hansen LL
    Lung Cancer; 2011 Feb; 71(2):130-6. PubMed ID: 20627446
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.
    Fahrer J; Frisch J; Nagel G; Kraus A; Dörsam B; Thomas AD; Reißig S; Waisman A; Kaina B
    Carcinogenesis; 2015 Oct; 36(10):1235-44. PubMed ID: 26243310
    [TBL] [Abstract][Full Text] [Related]  

  • 13. O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke.
    Christmann M; Kaina B
    Mutat Res; 2012 Aug; 736(1-2):64-74. PubMed ID: 21708177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alkylation damage in DNA and RNA--repair mechanisms and medical significance.
    Drabløs F; Feyzi E; Aas PA; Vaagbø CB; Kavli B; Bratlie MS; Peña-Diaz J; Otterlei M; Slupphaug G; Krokan HE
    DNA Repair (Amst); 2004 Nov; 3(11):1389-407. PubMed ID: 15380096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.
    Leng S; Wu G; Collins LB; Thomas CL; Tellez CS; Jauregui AR; Picchi MA; Zhang X; Juri DE; Desai D; Amin SG; Crowell RE; Stidley CA; Liu Y; Swenberg JA; Lin Y; Wathelet MG; Gilliland FD; Belinsky SA
    Cancer Res; 2015 Aug; 75(15):3108-17. PubMed ID: 26183928
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lung cancer risk and variation in MGMT activity and sequence.
    Povey AC; Margison GP; Santibáñez-Koref MF
    DNA Repair (Amst); 2007 Aug; 6(8):1134-44. PubMed ID: 17569600
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA-Targeted Inhibition of MGMT.
    Marsoner T; Schmidt OP; Triemer T; Luedtke NW
    Chembiochem; 2017 May; 18(10):894-898. PubMed ID: 28177192
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.
    Malley DS; Hamoudi RA; Kocialkowski S; Pearson DM; Collins VP; Ichimura K
    Acta Neuropathol; 2011 May; 121(5):651-61. PubMed ID: 21287394
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An O6-methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein.
    Morita R; Nakagawa N; Kuramitsu S; Masui R
    J Biochem; 2008 Aug; 144(2):267-77. PubMed ID: 18483064
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The L84F polymorphism in the O6-Methylguanine-DNA-Methyltransferase (MGMT) gene is associated with increased hypoxanthine phosphoribosyltransferase (HPRT) mutant frequency in lymphocytes of tobacco smokers.
    Hill CE; Wickliffe JK; Guerin AT; Kinslow CJ; Wolfe KJ; Ammenheuser MM; Abdel-Rahman SZ
    Pharmacogenet Genomics; 2007 Sep; 17(9):743-53. PubMed ID: 17700363
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.