These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 23392766)

  • 1. Mutational biosynthesis of tacrolimus analogues by fkbO deletion mutant of Streptomyces sp. KCTC 11604BP.
    Kim DH; Ryu JH; Lee KS; Lee BM; Lee MO; Lim SK; Maeng PJ
    Appl Microbiol Biotechnol; 2013 Jul; 97(13):5881-92. PubMed ID: 23392766
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutational biosynthesis of a FK506 analogue containing a non-natural starter unit.
    Ban YH; Lee JH; Gu GR; Lee B; Mo S; Kwon HJ; Yoon YJ
    Mol Biosyst; 2013 May; 9(5):944-7. PubMed ID: 23223556
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate.
    Andexer JN; Kendrew SG; Nur-e-Alam M; Lazos O; Foster TA; Zimmermann AS; Warneck TD; Suthar D; Coates NJ; Koehn FE; Skotnicki JS; Carter GT; Gregory MA; Martin CJ; Moss SJ; Leadlay PF; Wilkinson B
    Proc Natl Acad Sci U S A; 2011 Mar; 108(12):4776-81. PubMed ID: 21383123
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.
    Wu K; Chung L; Revill WP; Katz L; Reeves CD
    Gene; 2000 Jun; 251(1):81-90. PubMed ID: 10863099
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Application of a combined approach involving classical random mutagenesis and metabolic engineering to enhance FK506 production in Streptomyces sp. RM7011.
    Mo S; Lee SK; Jin YY; Oh CH; Suh JW
    Appl Microbiol Biotechnol; 2013 Apr; 97(7):3053-62. PubMed ID: 23053074
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic network model guided engineering ethylmalonyl-CoA pathway to improve ascomycin production in Streptomyces hygroscopicus var. ascomyceticus.
    Wang J; Wang C; Song K; Wen J
    Microb Cell Fact; 2017 Oct; 16(1):169. PubMed ID: 28974216
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects.
    Ban YH; Park SR; Yoon YJ
    J Ind Microbiol Biotechnol; 2016 Mar; 43(2-3):389-400. PubMed ID: 26342319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of fkbN in positive regulation and tcs7 in negative regulation of FK506 biosynthesis in Streptomyces sp. strain KCTC 11604BP.
    Mo S; Yoo YJ; Ban YH; Lee SK; Kim E; Suh JW; Yoon YJ
    Appl Environ Microbiol; 2012 Apr; 78(7):2249-55. PubMed ID: 22267670
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.
    Motamedi H; Shafiee A
    Eur J Biochem; 1998 Sep; 256(3):528-34. PubMed ID: 9780228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Target genes of the Streptomyces tsukubaensis FkbN regulator include most of the tacrolimus biosynthesis genes, a phosphopantetheinyl transferase and other PKS genes.
    Ordóñez-Robles M; Rodríguez-García A; Martín JF
    Appl Microbiol Biotechnol; 2016 Sep; 100(18):8091-103. PubMed ID: 27357227
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trends in the biosynthesis and production of the immunosuppressant tacrolimus (FK506).
    Barreiro C; Martínez-Castro M
    Appl Microbiol Biotechnol; 2014 Jan; 98(2):497-507. PubMed ID: 24272367
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roles of rapH and rapG in positive regulation of rapamycin biosynthesis in Streptomyces hygroscopicus.
    Kuscer E; Coates N; Challis I; Gregory M; Wilkinson B; Sheridan R; Petković H
    J Bacteriol; 2007 Jul; 189(13):4756-63. PubMed ID: 17468238
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Integration of parallel
    Qi H; Lv M; Song K; Wen J
    Biotechnol Bioeng; 2017 May; 114(5):1036-1044. PubMed ID: 27869289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies.
    Huang D; Xia M; Li S; Wen J; Jia X
    J Ind Microbiol Biotechnol; 2013 Sep; 40(9):1023-37. PubMed ID: 23779221
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.
    Mo S; Kim DH; Lee JH; Park JW; Basnet DB; Ban YH; Yoo YJ; Chen SW; Park SR; Choi EA; Kim E; Jin YY; Lee SK; Park JY; Liu Y; Lee MO; Lee KS; Kim SJ; Kim D; Park BC; Lee SG; Kwon HJ; Suh JW; Moore BS; Lim SK; Yoon YJ
    J Am Chem Soc; 2011 Feb; 133(4):976-85. PubMed ID: 21175203
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanistic implications for the chorismatase FkbO based on the crystal structure.
    Juneja P; Hubrich F; Diederichs K; Welte W; Andexer JN
    J Mol Biol; 2014 Jan; 426(1):105-15. PubMed ID: 24036425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New Sipanmycin Analogues Generated by Combinatorial Biosynthesis and Mutasynthesis Approaches Relying on the Substrate Flexibility of Key Enzymes in the Biosynthetic Pathway.
    Malmierca MG; Pérez-Victoria I; Martín J; Reyes F; Méndez C; Salas JA; Olano C
    Appl Environ Microbiol; 2020 Jan; 86(3):. PubMed ID: 31732573
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficient pyramidal arrangement of an ordered cosmid library: Rapid screening of genes of the tacrolimus-producer Streptomyces sp. ATCC 55098.
    Martínez-Castro M; Solera E; Martín JF; Barreiro C
    J Microbiol Methods; 2009 Aug; 78(2):150-4. PubMed ID: 19445977
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biosynthesis of rapamycin and its regulation: past achievements and recent progress.
    Park SR; Yoo YJ; Ban YH; Yoon YJ
    J Antibiot (Tokyo); 2010 Aug; 63(8):434-41. PubMed ID: 20588302
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative analysis of rapamycin biosynthesis clusters between Actinoplanes sp. N902-109 and Streptomyces hygroscopicus ATCC29253.
    Huang H; Ren SX; Yang S; Hu HF
    Chin J Nat Med; 2015 Feb; 13(2):90-8. PubMed ID: 25769891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.