407 related articles for article (PubMed ID: 23393161)
1. TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication.
Milenkovic D; Matic S; Kühl I; Ruzzenente B; Freyer C; Jemt E; Park CB; Falkenberg M; Larsson NG
Hum Mol Genet; 2013 May; 22(10):1983-93. PubMed ID: 23393161
[TBL] [Abstract][Full Text] [Related]
2. Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase.
Sen D; Nandakumar D; Tang GQ; Patel SS
J Biol Chem; 2012 Apr; 287(18):14545-56. PubMed ID: 22383523
[TBL] [Abstract][Full Text] [Related]
3. Stimulation of Variant Forms of the Mitochondrial DNA Helicase Twinkle by the Mitochondrial Single-Stranded DNA-Binding Protein.
Rodrigues APC; Oliveira MT
Methods Mol Biol; 2021; 2281():313-322. PubMed ID: 33847968
[TBL] [Abstract][Full Text] [Related]
4. Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling.
Goffart S; Cooper HM; Tyynismaa H; Wanrooij S; Suomalainen A; Spelbrink JN
Hum Mol Genet; 2009 Jan; 18(2):328-40. PubMed ID: 18971204
[TBL] [Abstract][Full Text] [Related]
5. Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
Khan I; Crouch JD; Bharti SK; Sommers JA; Carney SM; Yakubovskaya E; Garcia-Diaz M; Trakselis MA; Brosh RM
J Biol Chem; 2016 Jul; 291(27):14324-14339. PubMed ID: 27226550
[TBL] [Abstract][Full Text] [Related]
6. Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication.
Rajala N; Gerhold JM; Martinsson P; Klymov A; Spelbrink JN
Nucleic Acids Res; 2014 Jan; 42(2):952-67. PubMed ID: 24163258
[TBL] [Abstract][Full Text] [Related]
7. Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.
Wanrooij S; Goffart S; Pohjoismäki JL; Yasukawa T; Spelbrink JN
Nucleic Acids Res; 2007; 35(10):3238-51. PubMed ID: 17452351
[TBL] [Abstract][Full Text] [Related]
8. Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression.
Song L; Shan Y; Lloyd KC; Cortopassi GA
Hum Mol Genet; 2012 Dec; 21(23):5147-58. PubMed ID: 22949510
[TBL] [Abstract][Full Text] [Related]
9. TWINKLE and Other Human Mitochondrial DNA Helicases: Structure, Function and Disease.
Peter B; Falkenberg M
Genes (Basel); 2020 Apr; 11(4):. PubMed ID: 32283748
[TBL] [Abstract][Full Text] [Related]
10. The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ.
Johnson LC; Singh A; Patel SS
J Biol Chem; 2023 Jan; 299(1):102797. PubMed ID: 36528058
[TBL] [Abstract][Full Text] [Related]
11. Reduced stimulation of recombinant DNA polymerase γ and mitochondrial DNA (mtDNA) helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA replication in animal cells.
Oliveira MT; Kaguni LS
J Biol Chem; 2011 Nov; 286(47):40649-58. PubMed ID: 21953457
[TBL] [Abstract][Full Text] [Related]
12. Reconstitution of a minimal mtDNA replisome in vitro.
Korhonen JA; Pham XH; Pellegrini M; Falkenberg M
EMBO J; 2004 Jun; 23(12):2423-9. PubMed ID: 15167897
[TBL] [Abstract][Full Text] [Related]
13. Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB.
Hensen F; Potter A; van Esveld SL; Tarrés-Solé A; Chakraborty A; Solà M; Spelbrink JN
Nucleic Acids Res; 2019 Apr; 47(7):3680-3698. PubMed ID: 30715486
[TBL] [Abstract][Full Text] [Related]
14. Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element.
Jemt E; Persson Ö; Shi Y; Mehmedovic M; Uhler JP; Dávila López M; Freyer C; Gustafsson CM; Samuelsson T; Falkenberg M
Nucleic Acids Res; 2015 Oct; 43(19):9262-75. PubMed ID: 26253742
[TBL] [Abstract][Full Text] [Related]
15. Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase.
Kaur P; Longley MJ; Pan H; Wang W; Countryman P; Wang H; Copeland WC
J Biol Chem; 2020 Apr; 295(17):5564-5576. PubMed ID: 32213598
[TBL] [Abstract][Full Text] [Related]
16. In Vitro Assays of TWINKLE Function.
Uhler JP; Alexandersson U; Falkenberg M
Methods Mol Biol; 2023; 2615():191-201. PubMed ID: 36807793
[TBL] [Abstract][Full Text] [Related]
17. The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function.
Farge G; Pham XH; Holmlund T; Khorostov I; Falkenberg M
Nucleic Acids Res; 2007; 35(3):902-11. PubMed ID: 17251196
[TBL] [Abstract][Full Text] [Related]
18. The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis.
Jemt E; Farge G; Bäckström S; Holmlund T; Gustafsson CM; Falkenberg M
Nucleic Acids Res; 2011 Nov; 39(21):9238-49. PubMed ID: 21840902
[TBL] [Abstract][Full Text] [Related]
19. Structural basis for adPEO-causing mutations in the mitochondrial TWINKLE helicase.
Peter B; Farge G; Pardo-Hernandez C; Tångefjord S; Falkenberg M
Hum Mol Genet; 2019 Apr; 28(7):1090-1099. PubMed ID: 30496414
[TBL] [Abstract][Full Text] [Related]
20. Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM.
Riccio AA; Bouvette J; Longley MJ; Krahn JM; Borgnia MJ; Copeland WC
Methods; 2022 Sep; 205():263-270. PubMed ID: 35779765
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]