192 related articles for article (PubMed ID: 23393228)
1. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Doktorova TY; Yildirimman R; Vinken M; Vilardell M; Vanhaecke T; Gmuender H; Bort R; Brolen G; Holmgren G; Li R; Chesne C; van Delft J; Kleinjans J; Castell J; Bjorquist P; Herwig R; Rogiers V
Carcinogenesis; 2013 Jun; 34(6):1393-402. PubMed ID: 23393228
[TBL] [Abstract][Full Text] [Related]
2. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Doktorova TY; Ellinger-Ziegelbauer H; Vinken M; Vanhaecke T; van Delft J; Kleinjans J; Ahr HJ; Rogiers V
Arch Toxicol; 2012 Sep; 86(9):1399-411. PubMed ID: 22484513
[TBL] [Abstract][Full Text] [Related]
3. Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
Jennen DG; Magkoufopoulou C; Ketelslegers HB; van Herwijnen MH; Kleinjans JC; van Delft JH
Toxicol Sci; 2010 May; 115(1):66-79. PubMed ID: 20106945
[TBL] [Abstract][Full Text] [Related]
4. Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.
Mathijs K; Brauers KJ; Jennen DG; Boorsma A; van Herwijnen MH; Gottschalk RW; Kleinjans JC; van Delft JH
Toxicol Sci; 2009 Dec; 112(2):374-84. PubMed ID: 19770486
[TBL] [Abstract][Full Text] [Related]
5. Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes.
Rieswijk L; Brauers KJ; Coonen ML; van Breda SG; Jennen DG; Kleinjans JC
Mutagenesis; 2015 Nov; 30(6):771-84. PubMed ID: 25976910
[TBL] [Abstract][Full Text] [Related]
6. Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
Jetten MJ; Kleinjans JC; Claessen SM; Chesné C; van Delft JH
Toxicol In Vitro; 2013 Oct; 27(7):2031-40. PubMed ID: 23911569
[TBL] [Abstract][Full Text] [Related]
7. Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells.
Harris AJ; Dial SL; Casciano DA
Mutat Res; 2004 May; 549(1-2):79-99. PubMed ID: 15120964
[TBL] [Abstract][Full Text] [Related]
8. Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.
van Kesteren PC; Zwart PE; Schaap MM; Pronk TE; van Herwijnen MH; Kleinjans JC; Bokkers BG; Godschalk RW; Zeilmaker MJ; van Steeg H; Luijten M
Arch Toxicol; 2013 Mar; 87(3):505-15. PubMed ID: 23052197
[TBL] [Abstract][Full Text] [Related]
9. Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver.
Ellinger-Ziegelbauer H; Stuart B; Wahle B; Bomann W; Ahr HJ
Mutat Res; 2005 Aug; 575(1-2):61-84. PubMed ID: 15890375
[TBL] [Abstract][Full Text] [Related]
10. Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks.
Rieswijk L; Lizarraga D; Brauers KJ; Kleinjans JC; van Delft JH
Mutagenesis; 2014 Jan; 29(1):17-26. PubMed ID: 24280081
[TBL] [Abstract][Full Text] [Related]
11. Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.
Doktorova TY; Ellinger-Ziegelbauer H; Vinken M; Vanhaecke T; van Delft J; Kleinjans J; Ahr HJ; Rogiers V
Arch Toxicol; 2012 Nov; 86(11):1703-15. PubMed ID: 23052194
[TBL] [Abstract][Full Text] [Related]
12. Oxidative Stress Mechanisms Do Not Discriminate between Genotoxic and Nongenotoxic Liver Carcinogens.
Deferme L; Wolters J; Claessen S; Briedé J; Kleinjans J
Chem Res Toxicol; 2015 Aug; 28(8):1636-46. PubMed ID: 26198647
[TBL] [Abstract][Full Text] [Related]
13. Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity.
Rieswijk L; Brauers KJ; Coonen ML; Jennen DG; van Breda SG; Kleinjans JC
Mutagenesis; 2016 Sep; 31(5):603-15. PubMed ID: 27338304
[TBL] [Abstract][Full Text] [Related]
14. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
Josse R; Dumont J; Fautrel A; Robin MA; Guillouzo A
Toxicol Appl Pharmacol; 2012 Jan; 258(2):176-87. PubMed ID: 22100608
[TBL] [Abstract][Full Text] [Related]
15. Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.
Schaap MM; Zwart EP; Wackers PF; Huijskens I; van de Water B; Breit TM; van Steeg H; Jonker MJ; Luijten M
Arch Toxicol; 2012 Nov; 86(11):1717-27. PubMed ID: 22710402
[TBL] [Abstract][Full Text] [Related]
16. Differential gene expression profiling between genotoxic and non-genotoxic hepatocarcinogens in young rat liver determined by quantitative real-time PCR and principal component analysis.
Suenaga K; Takasawa H; Watanabe T; Wako Y; Suzuki T; Hamada S; Furihata C
Mutat Res; 2013 Feb; 751(1):73-83. PubMed ID: 23183053
[TBL] [Abstract][Full Text] [Related]
17. Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling.
van Delft JH; van Agen E; van Breda SG; Herwijnen MH; Staal YC; Kleinjans JC
Carcinogenesis; 2004 Jul; 25(7):1265-76. PubMed ID: 14963013
[TBL] [Abstract][Full Text] [Related]
18. A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.
Schaap MM; Wackers PF; Zwart EP; Huijskens I; Jonker MJ; Hendriks G; Breit TM; van Steeg H; van de Water B; Luijten M
Arch Toxicol; 2015 Dec; 89(12):2413-27. PubMed ID: 25270620
[TBL] [Abstract][Full Text] [Related]
19. Characteristic expression profiles induced by genotoxic carcinogens in rat liver.
Ellinger-Ziegelbauer H; Stuart B; Wahle B; Bomann W; Ahr HJ
Toxicol Sci; 2004 Jan; 77(1):19-34. PubMed ID: 14600272
[TBL] [Abstract][Full Text] [Related]
20. A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo.
Magkoufopoulou C; Claessen SM; Tsamou M; Jennen DG; Kleinjans JC; van Delft JH
Carcinogenesis; 2012 Jul; 33(7):1421-9. PubMed ID: 22623647
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]