BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 23395820)

  • 1. EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner.
    Nadanaka S; Zhou S; Kagiyama S; Shoji N; Sugahara K; Sugihara K; Asano M; Kitagawa H
    J Biol Chem; 2013 Mar; 288(13):9321-33. PubMed ID: 23395820
    [TBL] [Abstract][Full Text] [Related]  

  • 2. EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.
    Nadanaka S; Kitagawa H
    Matrix Biol; 2014 Apr; 35():18-24. PubMed ID: 24176719
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate.
    Kitagawa H; Shimakawa H; Sugahara K
    J Biol Chem; 1999 May; 274(20):13933-7. PubMed ID: 10318803
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biosynthesis of heparan sulfate in EXT1-deficient cells.
    Okada M; Nadanaka S; Shoji N; Tamura J; Kitagawa H
    Biochem J; 2010 May; 428(3):463-71. PubMed ID: 20377530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of phosphatase that dephosphorylates xylose in the glycosaminoglycan-protein linkage region of proteoglycans.
    Koike T; Izumikawa T; Sato B; Kitagawa H
    J Biol Chem; 2014 Mar; 289(10):6695-6708. PubMed ID: 24425863
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced Expression of EXTL2, a Member of the Exostosin (EXT) Family of Glycosyltransferases, in Human Embryonic Kidney 293 Cells Results in Longer Heparan Sulfate Chains.
    Katta K; Imran T; Busse-Wicher M; Grønning M; Czajkowski S; Kusche-Gullberg M
    J Biol Chem; 2015 May; 290(21):13168-77. PubMed ID: 25829497
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes.
    Nadanaka S; Kagiyama S; Kitagawa H
    Biochem J; 2013 Aug; 454(1):133-45. PubMed ID: 23734945
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.
    Kim BT; Kitagawa H; Tamura J; Saito T; Kusche-Gullberg M; Lindahl U; Sugahara K
    Proc Natl Acad Sci U S A; 2001 Jun; 98(13):7176-81. PubMed ID: 11390981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate.
    Kitagawa H; Egusa N; Tamura JI; Kusche-Gullberg M; Lindahl U; Sugahara K
    J Biol Chem; 2001 Feb; 276(7):4834-8. PubMed ID: 11121397
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation.
    Busse M; Feta A; Presto J; Wilén M; Grønning M; Kjellén L; Kusche-Gullberg M
    J Biol Chem; 2007 Nov; 282(45):32802-10. PubMed ID: 17761672
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GlcUAβ1-3Galβ1-3Galβ1-4Xyl(2-O-phosphate) is the preferred substrate for chondroitin N-acetylgalactosaminyltransferase-1.
    Izumikawa T; Sato B; Mikami T; Tamura J; Igarashi M; Kitagawa H
    J Biol Chem; 2015 Feb; 290(9):5438-48. PubMed ID: 25568321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2.
    Nadanaka S; Kitagawa H
    Biochim Biophys Acta Gen Subj; 2018 Apr; 1862(4):791-799. PubMed ID: 29305908
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region.
    Koike T; Izumikawa T; Tamura J; Kitagawa H
    Biochem J; 2009 Jun; 421(2):157-62. PubMed ID: 19473117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate.
    Lind T; Tufaro F; McCormick C; Lindahl U; Lidholt K
    J Biol Chem; 1998 Oct; 273(41):26265-8. PubMed ID: 9756849
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Demonstration of the immature glycosaminoglycan tetrasaccharide sequence GlcAbeta1-3Galbeta1-3Galbeta1-4Xyl on recombinant soluble human alpha-thrombomodulin. An oligosaccharide structure on a "part-time" proteoglycan.
    Nadanaka S; Kitagawa H; Sugahara K
    J Biol Chem; 1998 Dec; 273(50):33728-34. PubMed ID: 9837960
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and characterization of a novel member of the EXT gene family, EXTL2.
    Wuyts W; Van Hul W; Hendrickx J; Speleman F; Wauters J; De Boulle K; Van Roy N; Van Agtmael T; Bossuyt P; Willems PJ
    Eur J Hum Genet; 1997; 5(6):382-9. PubMed ID: 9450183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulfation of the galactose residues in the glycosaminoglycan-protein linkage region by recombinant human chondroitin 6-O-sulfotransferase-1.
    Kitagawa H; Tsutsumi K; Ikegami-Kuzuhara A; Nadanaka S; Goto F; Ogawa T; Sugahara K
    J Biol Chem; 2008 Oct; 283(41):27438-27443. PubMed ID: 18697746
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of glycosaminoglycan-protein linkage tetrasaccharides as acceptors for GalNAc- and GlcNAc-transferases from mouse mastocytoma.
    Lidholt K; Fjelstad M; Lindahl U; Goto F; Ogawa T; Kitagawa H; Sugahara K
    Glycoconj J; 1997 Sep; 14(6):737-42. PubMed ID: 9337087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation analysis of hereditary multiple exostoses in the Chinese.
    Xu L; Xia J; Jiang H; Zhou J; Li H; Wang D; Pan Q; Long Z; Fan C; Deng HX
    Hum Genet; 1999; 105(1-2):45-50. PubMed ID: 10480354
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.
    Han C; Belenkaya TY; Khodoun M; Tauchi M; Lin X; Lin X
    Development; 2004 Apr; 131(7):1563-75. PubMed ID: 14998928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.