BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 23395885)

  • 1. GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells.
    Schwartz-Roberts JL; Shajahan AN; Cook KL; Wärri A; Abu-Asab M; Clarke R
    Mol Cancer Ther; 2013 Apr; 12(4):448-59. PubMed ID: 23395885
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis.
    Carew JS; Espitia CM; Esquivel JA; Mahalingam D; Kelly KR; Reddy G; Giles FJ; Nawrocki ST
    J Biol Chem; 2011 Feb; 286(8):6602-13. PubMed ID: 21148553
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy.
    Heidari N; Hicks MA; Harada H
    Cell Death Dis; 2010 Sep; 1(9):e76. PubMed ID: 21364679
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes.
    Basit F; Cristofanon S; Fulda S
    Cell Death Differ; 2013 Sep; 20(9):1161-73. PubMed ID: 23744296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik.
    Chen S; Zhou L; Zhang Y; Leng Y; Pei XY; Lin H; Jones R; Orlowski RZ; Dai Y; Grant S
    Mol Cell Biol; 2014 Sep; 34(18):3435-49. PubMed ID: 25002530
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells.
    Nehra R; Riggins RB; Shajahan AN; Zwart A; Crawford AC; Clarke R
    FASEB J; 2010 Jun; 24(6):2040-55. PubMed ID: 20154269
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophagy and lysosomal related protein expression patterns in human glioblastoma.
    Giatromanolaki A; Sivridis E; Mitrakas A; Kalamida D; Zois CE; Haider S; Piperidou C; Pappa A; Gatter KC; Harris AL; Koukourakis MI
    Cancer Biol Ther; 2014; 15(11):1468-78. PubMed ID: 25482944
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy facilitates the progression of ERalpha-positive breast cancer cells to antiestrogen resistance.
    Schoenlein PV; Periyasamy-Thandavan S; Samaddar JS; Jackson WH; Barrett JT
    Autophagy; 2009 Apr; 5(3):400-3. PubMed ID: 19221464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells.
    Periyasamy-Thandavan S; Jackson WH; Samaddar JS; Erickson B; Barrett JR; Raney L; Gopal E; Ganapathy V; Hill WD; Bhalla KN; Schoenlein PV
    Autophagy; 2010 Jan; 6(1):19-35. PubMed ID: 20110775
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.
    Su JC; Tseng PH; Hsu CY; Tai WT; Huang JW; Ko CH; Lin MW; Liu CY; Chen KF; Shiau CW
    Oncotarget; 2014 Jul; 5(13):4909-19. PubMed ID: 24952874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis.
    Jakhar R; Paul S; Bhardwaj M; Kang SC
    Cancer Lett; 2016 Mar; 372(1):89-100. PubMed ID: 26739061
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.
    Boyer-Guittaut M; Poillet L; Liang Q; Bôle-Richard E; Ouyang X; Benavides GA; Chakrama FZ; Fraichard A; Darley-Usmar VM; Despouy G; Jouvenot M; Delage-Mourroux R; Zhang J
    Autophagy; 2014 Jun; 10(6):986-1003. PubMed ID: 24879149
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes.
    Ji C; Tang M; Zeidler C; Höhfeld J; Johnson GV
    Autophagy; 2019 Jul; 15(7):1199-1213. PubMed ID: 30744518
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells.
    Qiu W; Su M; Xie F; Ai J; Ren Y; Zhang J; Guan R; He W; Gong Y; Guo Y
    Cell Death Dis; 2014 Mar; 5(3):e1123. PubMed ID: 24625982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells.
    Yu L; Wu WK; Gu C; Zhong D; Zhao X; Kong Y; Lin Q; Chan MT; Zhou Z; Liu S
    Oncotarget; 2016 Mar; 7(12):14693-707. PubMed ID: 26910910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.
    Sarkar C; Zhao Z; Aungst S; Sabirzhanov B; Faden AI; Lipinski MM
    Autophagy; 2014; 10(12):2208-22. PubMed ID: 25484084
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Manumycin A inhibits triple-negative breast cancer growth through LC3-mediated cytoplasmic vacuolation death.
    Singha PK; Pandeswara S; Venkatachalam MA; Saikumar P
    Cell Death Dis; 2013 Jan; 4(1):e457. PubMed ID: 23328664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.
    Rui YN; Xu Z; Chen Z; Zhang S
    Autophagy; 2015; 11(5):812-32. PubMed ID: 25984893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of autophagy-related markers beclin-1, light chain 3A, light chain 3B and p62 according to the molecular subtype of breast cancer.
    Choi J; Jung W; Koo JS
    Histopathology; 2013 Jan; 62(2):275-86. PubMed ID: 23134379
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Divergent roles of BECN1 in LC3 lipidation and autophagosomal function.
    He R; Peng J; Yuan P; Xu F; Wei W
    Autophagy; 2015; 11(5):740-7. PubMed ID: 25955014
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.