232 related articles for article (PubMed ID: 23396364)
1. Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities.
Patel RA; Liu Y; Wang B; Li R; Sebti SM
Oncogene; 2014 Jan; 33(5):550-5. PubMed ID: 23396364
[TBL] [Abstract][Full Text] [Related]
2. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
Patel RA; Forinash KD; Pireddu R; Sun Y; Sun N; Martin MP; Schönbrunn E; Lawrence NJ; Sebti SM
Cancer Res; 2012 Oct; 72(19):5025-34. PubMed ID: 22846914
[TBL] [Abstract][Full Text] [Related]
3. Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway.
Sun J; Zhang D; Zheng Y; Zhao Q; Zheng M; Kovacevic Z; Richardson DR
Mol Pharmacol; 2013 Feb; 83(2):454-69. PubMed ID: 23188716
[TBL] [Abstract][Full Text] [Related]
4. Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors.
Li R; Martin MP; Liu Y; Wang B; Patel RA; Zhu JY; Sun N; Pireddu R; Lawrence NJ; Li J; Haura EB; Sung SS; Guida WC; Schonbrunn E; Sebti SM
J Med Chem; 2012 Mar; 55(5):2474-8. PubMed ID: 22272748
[TBL] [Abstract][Full Text] [Related]
5. Rho kinase collaborates with p21-activated kinase to regulate actin polymerization and contraction in airway smooth muscle.
Zhang W; Bhetwal BP; Gunst SJ
J Physiol; 2018 Aug; 596(16):3617-3635. PubMed ID: 29746010
[TBL] [Abstract][Full Text] [Related]
6. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment.
Shi J; Wu X; Surma M; Vemula S; Zhang L; Yang Y; Kapur R; Wei L
Cell Death Dis; 2013 Feb; 4(2):e483. PubMed ID: 23392171
[TBL] [Abstract][Full Text] [Related]
7. Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth.
Rath N; Munro J; Cutiongco MF; Jagiełło A; Gadegaard N; McGarry L; Unbekandt M; Michalopoulou E; Kamphorst JJ; Sumpton D; Mackay G; Vennin C; Pajic M; Timpson P; Olson MF
Cancer Res; 2018 Jun; 78(12):3321-3336. PubMed ID: 29669760
[TBL] [Abstract][Full Text] [Related]
8. RKI-1447 suppresses colorectal carcinoma cell growth via disrupting cellular bioenergetics and mitochondrial dynamics.
Li L; Chen Q; Yu Y; Chen H; Lu M; Huang Y; Li P; Chang H
J Cell Physiol; 2020 Jan; 235(1):254-266. PubMed ID: 31237697
[TBL] [Abstract][Full Text] [Related]
9. A novel small-molecule MRCK inhibitor blocks cancer cell invasion.
Unbekandt M; Croft DR; Crighton D; Mezna M; McArthur D; McConnell P; Schüttelkopf AW; Belshaw S; Pannifer A; Sime M; Bower J; Drysdale M; Olson MF
Cell Commun Signal; 2014 Oct; 12():54. PubMed ID: 25288205
[TBL] [Abstract][Full Text] [Related]
10. Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA/ROCK and CDC42/MRCK.
Wu Q; Ma X; Jin Z; Ni R; Pan Y; Yang G
J Ethnopharmacol; 2023 Oct; 315():116644. PubMed ID: 37196814
[TBL] [Abstract][Full Text] [Related]
11. Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells.
Eitaki M; Yamamori T; Meike S; Yasui H; Inanami O
BMC Cancer; 2012 Oct; 12():469. PubMed ID: 23057787
[TBL] [Abstract][Full Text] [Related]
12. Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway.
Kidera Y; Tsubaki M; Yamazoe Y; Shoji K; Nakamura H; Ogaki M; Satou T; Itoh T; Isozaki M; Kaneko J; Tanimori Y; Yanae M; Nishida S
J Exp Clin Cancer Res; 2010 Sep; 29(1):127. PubMed ID: 20843370
[TBL] [Abstract][Full Text] [Related]
13. Plumbagin reduces osteopontin-induced invasion through inhibiting the Rho-associated kinase signaling pathway in A549 cells and suppresses osteopontin-induced lung metastasis in BalB/c mice.
Kang CG; Im E; Lee HJ; Lee EO
Bioorg Med Chem Lett; 2017 May; 27(9):1914-1918. PubMed ID: 28359791
[TBL] [Abstract][Full Text] [Related]
14. Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation.
Serizawa N; Tian J; Fukada H; Baghy K; Scott F; Chen X; Kiss Z; Olson K; Hsu D; Liu FT; Török NJ; Zhao B; Jiang JX
Lab Invest; 2015 Oct; 95(10):1145-56. PubMed ID: 26146960
[TBL] [Abstract][Full Text] [Related]
15. Activation of Rho kinase isoforms in lung endothelial cells during inflammation.
Mong PY; Wang Q
J Immunol; 2009 Feb; 182(4):2385-94. PubMed ID: 19201893
[TBL] [Abstract][Full Text] [Related]
16. Increase in cell motility by carbon ion irradiation via the Rho signaling pathway and its inhibition by the ROCK inhibitor Y-27632 in lung adenocarcinoma A549 cells.
Murata K; Noda SE; Oike T; Takahashi A; Yoshida Y; Suzuki Y; Ohno T; Funayama T; Kobayashi Y; Takahashi T; Nakano T
J Radiat Res; 2014 Jul; 55(4):658-64. PubMed ID: 24659807
[TBL] [Abstract][Full Text] [Related]
17. ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration.
Ortíz-López L; Morales-Mulia S; Ramírez-Rodríguez G; Benítez-King G
J Pineal Res; 2009 Jan; 46(1):15-21. PubMed ID: 18482340
[TBL] [Abstract][Full Text] [Related]
18. Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells.
Sun K; Duan X; Cai H; Liu X; Yang Y; Li M; Zhang X; Wang J
Clin Exp Med; 2016 Feb; 16(1):37-47. PubMed ID: 25596714
[TBL] [Abstract][Full Text] [Related]
19. ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion.
Vigil D; Kim TY; Plachco A; Garton AJ; Castaldo L; Pachter JA; Dong H; Chen X; Tokar B; Campbell SL; Der CJ
Cancer Res; 2012 Oct; 72(20):5338-47. PubMed ID: 22942252
[TBL] [Abstract][Full Text] [Related]
20. Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells.
Chaturvedi LS; Marsh HM; Basson MD
Am J Physiol Cell Physiol; 2011 Nov; 301(5):C1224-38. PubMed ID: 21849669
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]