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2. Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase. Ogushi F; Hubbard RC; Vogelmeier C; Fells GA; Crystal RG J Clin Invest; 1991 Mar; 87(3):1060-5. PubMed ID: 1999486 [TBL] [Abstract][Full Text] [Related]
3. Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase. Hubbard RC; Ogushi F; Fells GA; Cantin AM; Jallat S; Courtney M; Crystal RG J Clin Invest; 1987 Nov; 80(5):1289-95. PubMed ID: 2824559 [TBL] [Abstract][Full Text] [Related]
4. Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase. Ogushi F; Fells GA; Hubbard RC; Straus SD; Crystal RG J Clin Invest; 1987 Nov; 80(5):1366-74. PubMed ID: 3500183 [TBL] [Abstract][Full Text] [Related]
6. Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages. Hubbard RC; Fells G; Gadek J; Pacholok S; Humes J; Crystal RG J Clin Invest; 1991 Sep; 88(3):891-7. PubMed ID: 1653278 [TBL] [Abstract][Full Text] [Related]
7. The elastase/alpha 1-proteinase inhibitor balance in the lung. A review. Virca GD; Schnebli HP Schweiz Med Wochenschr; 1984 Jun; 114(25):895-8. PubMed ID: 6379867 [TBL] [Abstract][Full Text] [Related]
8. Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor. Vogelmeier C; Hubbard RC; Fells GA; Schnebli HP; Thompson RC; Fritz H; Crystal RG J Clin Invest; 1991 Feb; 87(2):482-8. PubMed ID: 1671391 [TBL] [Abstract][Full Text] [Related]
9. [Trypsin and pancreatic elastase-inhibitory capacity of serum and bronchoalveolar lavage fluid of smokers, ex-smokers and nonsmokers]. Ebert W; Trefz G; Heck B; Schulz V Pneumologie; 1990 Feb; 44 Suppl 1():267-8. PubMed ID: 2367387 [TBL] [Abstract][Full Text] [Related]
10. The mucosal defence capacity against proteolytic leukocyte enzymes. Tegner H; Fryksmark U; Ohlsson K Eur J Respir Dis Suppl; 1985; 139():62-5. PubMed ID: 3876236 [TBL] [Abstract][Full Text] [Related]
11. Analysis of secretory leukocyte protease inhibitor (SLPI) in bronchial secretions from patients with hypersecretory respiratory diseases. Kouchi I; Yasuoka S; Ueda Y; Ogura T Tokushima J Exp Med; 1993 Jun; 40(1-2):95-107. PubMed ID: 8105562 [TBL] [Abstract][Full Text] [Related]
12. Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population. de Santi MM; Martorana PA; Cavarra E; Lungarella G Lab Invest; 1995 Jul; 73(1):40-7. PubMed ID: 7603039 [TBL] [Abstract][Full Text] [Related]
13. Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema. Abboud RT; Vimalanathan S Int J Tuberc Lung Dis; 2008 Apr; 12(4):361-7. PubMed ID: 18371259 [TBL] [Abstract][Full Text] [Related]
14. Potency of antileukoprotease and alpha 1-antitrypsin to inhibit degradation of fibrinogen by adherent polymorphonuclear leukocytes from normal subjects and patients with chronic granulomatous disease. Stolk J; Davies P; Kramps JA; Dijkman JH; Humes JJ; Knight WB; Green BG; Mumford R; Bonney RJ; Hanlon WA Am J Respir Cell Mol Biol; 1992 May; 6(5):521-6. PubMed ID: 1316132 [TBL] [Abstract][Full Text] [Related]
15. Neutrophil recruitment into the lungs is associated with increased lung elastase burden, decreased lung elastin, and emphysema in alpha 1 proteinase inhibitor-deficient mice. Cavarra E; Martorana PA; Gambelli F; de Santi M; van Even P; Lungarella G Lab Invest; 1996 Aug; 75(2):273-80. PubMed ID: 8765327 [TBL] [Abstract][Full Text] [Related]
16. Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. Birrer P; McElvaney NG; Rüdeberg A; Sommer CW; Liechti-Gallati S; Kraemer R; Hubbard R; Crystal RG Am J Respir Crit Care Med; 1994 Jul; 150(1):207-13. PubMed ID: 7912987 [TBL] [Abstract][Full Text] [Related]
17. Contribution of additional elastase inhibitors other than alpha 1-protease inhibitor and bronchial antileukoprotease to neutrophil elastase inhibiting capacity of bronchoalveolar lavage. Abboud R; Tsang A; Taller M Ann N Y Acad Sci; 1991; 624():315. PubMed ID: 2064232 [No Abstract] [Full Text] [Related]
18. The antielastase screen of the lower respiratory tract of alpha 1-proteinase inhibitor-sufficient patients with emphysema or pneumothorax. Gast A; Dietemann-Molard A; Pelletier A; Pauli G; Bieth JG Am Rev Respir Dis; 1990 Apr; 141(4 Pt 1):880-3. PubMed ID: 2327650 [TBL] [Abstract][Full Text] [Related]
19. Alpha 1-proteinase inhibitor and mucus proteinase inhibitor in human lung emphysema. Trefz G; Schliesser J; Heck B; Schulz V; Ebert W Clin Investig; 1992; 70(3-4):269-76. PubMed ID: 1521041 [TBL] [Abstract][Full Text] [Related]
20. [A study of antielastase activity in the development of pulmonary emphysema in a family with alpha 1-antitrypsin deficiency]. Kishi F; Kakinoki A Nihon Kyobu Shikkan Gakkai Zasshi; 1989 May; 27(5):565-70. PubMed ID: 2615095 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]