BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 23401857)

  • 1. Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.
    Zhang X; Lavoie G; Fort L; Huttlin EL; Tcherkezian J; Galan JA; Gu H; Gygi SP; Carreno S; Roux PP
    Mol Cell Biol; 2013 Apr; 33(8):1657-70. PubMed ID: 23401857
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.
    Yang S; Ji M; Zhang L; Chen Y; Wennmann DO; Kremerskothen J; Dong J
    Cell Signal; 2014 Feb; 26(2):343-51. PubMed ID: 24269383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.
    Zhang X; Lavoie G; Méant A; Aubert L; Cargnello M; Haman A; Hoang T; Roux PP
    Mol Cell Biol; 2017 Apr; 37(7):. PubMed ID: 28096188
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
    Nyga R; Pecquet C; Harir N; Gu H; Dhennin-Duthille I; Régnier A; Gouilleux-Gruart V; Lassoued K; Gouilleux F
    Biochem J; 2005 Aug; 390(Pt 1):359-66. PubMed ID: 15833084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation.
    Wang L; Xue J; Zadorozny EV; Robinson LJ
    Cell Signal; 2008 Oct; 20(10):1890-9. PubMed ID: 18644434
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner.
    Bongartz H; Gille K; Hessenkemper W; Mandel K; Lewitzky M; Feller SM; Schaper F
    Cell Commun Signal; 2019 Oct; 17(1):135. PubMed ID: 31651330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation.
    Herrera Abreu MT; Hughes WE; Mele K; Lyons RJ; Rickwood D; Browne BC; Bennett HL; Vallotton P; Brummer T; Daly RJ
    Mol Biol Cell; 2011 Jan; 22(1):105-16. PubMed ID: 21118992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms.
    Zhou L; Talebian A; Meakin SO
    J Mol Neurosci; 2015 Mar; 55(3):663-77. PubMed ID: 25159185
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.
    Liu Y; Jenkins B; Shin JL; Rohrschneider LR
    Mol Cell Biol; 2001 May; 21(9):3047-56. PubMed ID: 11287610
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2.
    Craddock BL; Hobbs J; Edmead CE; Welham MJ
    J Biol Chem; 2001 Jun; 276(26):24274-83. PubMed ID: 11335710
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.
    Roux PP; Shahbazian D; Vu H; Holz MK; Cohen MS; Taunton J; Sonenberg N; Blenis J
    J Biol Chem; 2007 May; 282(19):14056-64. PubMed ID: 17360704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor.
    Frigault MM; Naujokas MA; Park M
    J Cell Physiol; 2008 Mar; 214(3):694-705. PubMed ID: 17894413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A role for the scaffolding adapter GAB2 in breast cancer.
    Bentires-Alj M; Gil SG; Chan R; Wang ZC; Wang Y; Imanaka N; Harris LN; Richardson A; Neel BG; Gu H
    Nat Med; 2006 Jan; 12(1):114-21. PubMed ID: 16369543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V; Scott RP; Ibáñez CF
    J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase.
    Futami M; Zhu QS; Whichard ZL; Xia L; Ke Y; Neel BG; Feng GS; Corey SJ
    Blood; 2011 Jul; 118(4):1077-86. PubMed ID: 21636860
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1.
    Zhao C; Yu DH; Shen R; Feng GS
    J Biol Chem; 1999 Jul; 274(28):19649-54. PubMed ID: 10391903
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.
    Voena C; Conte C; Ambrogio C; Boeri Erba E; Boccalatte F; Mohammed S; Jensen ON; Palestro G; Inghirami G; Chiarle R
    Cancer Res; 2007 May; 67(9):4278-86. PubMed ID: 17483340
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical role for Gab2 in transformation by BCR/ABL.
    Sattler M; Mohi MG; Pride YB; Quinnan LR; Malouf NA; Podar K; Gesbert F; Iwasaki H; Li S; Van Etten RA; Gu H; Griffin JD; Neel BG
    Cancer Cell; 2002 Jun; 1(5):479-92. PubMed ID: 12124177
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation.
    Arnaud M; Crouin C; Deon C; Loyaux D; Bertoglio J
    J Immunol; 2004 Sep; 173(6):3962-71. PubMed ID: 15356145
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.
    Abe Y; Yoon SO; Kubota K; Mendoza MC; Gygi SP; Blenis J
    J Biol Chem; 2009 May; 284(22):14939-48. PubMed ID: 19332537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.