BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 23403946)

  • 1. Asparagine synthetase: regulation by cell stress and involvement in tumor biology.
    Balasubramanian MN; Butterworth EA; Kilberg MS
    Am J Physiol Endocrinol Metab; 2013 Apr; 304(8):E789-99. PubMed ID: 23403946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
    Gjymishka A; Su N; Kilberg MS
    Biochem J; 2009 Feb; 417(3):695-703. PubMed ID: 18840095
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Asparagine synthetase: Function, structure, and role in disease.
    Lomelino CL; Andring JT; McKenna R; Kilberg MS
    J Biol Chem; 2017 Dec; 292(49):19952-19958. PubMed ID: 29084849
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion.
    Jiang J; Srivastava S; Seim G; Pavlova NN; King B; Zou L; Zhang C; Zhong M; Feng H; Kapur R; Wek RC; Fan J; Zhang J
    J Biol Chem; 2019 Dec; 294(49):18674-18684. PubMed ID: 31659118
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized histone acetylation.
    Chen H; Pan YX; Dudenhausen EE; Kilberg MS
    J Biol Chem; 2004 Dec; 279(49):50829-39. PubMed ID: 15385533
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of asparagine synthetase on nutrient metabolism in pancreatic disease.
    Tsai CY; Kilberg MS; Husain SZ
    Pancreatology; 2020 Sep; 20(6):1029-1034. PubMed ID: 32800652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.
    Williams RT; Guarecuco R; Gates LA; Barrows D; Passarelli MC; Carey B; Baudrier L; Jeewajee S; La K; Prizer B; Malik S; Garcia-Bermudez J; Zhu XG; Cantor J; Molina H; Carroll T; Roeder RG; Abdel-Wahab O; Allis CD; Birsoy K
    Cell Metab; 2020 Apr; 31(4):852-861.e6. PubMed ID: 32268116
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter.
    Pan Y; Chen H; Siu F; Kilberg MS
    J Biol Chem; 2003 Oct; 278(40):38402-12. PubMed ID: 12881527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene.
    Su N; Kilberg MS
    J Biol Chem; 2008 Dec; 283(50):35106-17. PubMed ID: 18940792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response.
    Nakamura A; Nambu T; Ebara S; Hasegawa Y; Toyoshima K; Tsuchiya Y; Tomita D; Fujimoto J; Kurasawa O; Takahara C; Ando A; Nishigaki R; Satomi Y; Hata A; Hara T
    Proc Natl Acad Sci U S A; 2018 Aug; 115(33):E7776-E7785. PubMed ID: 30061420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.
    Gwinn DM; Lee AG; Briones-Martin-Del-Campo M; Conn CS; Simpson DR; Scott AI; Le A; Cowan TM; Ruggero D; Sweet-Cordero EA
    Cancer Cell; 2018 Jan; 33(1):91-107.e6. PubMed ID: 29316436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.
    Balasubramanian MN; Shan J; Kilberg MS
    Biochem J; 2013 Jan; 449(1):219-29. PubMed ID: 22978410
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia.
    Chiu M; Taurino G; Bianchi MG; Kilberg MS; Bussolati O
    Front Oncol; 2019; 9():1480. PubMed ID: 31998641
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Asparagine Synthetase Is Highly Expressed at Baseline in the Pancreas Through Heightened PERK Signaling.
    Mukherjee A; Ahmed N; Rose FT; Ahmad AN; Javed TA; Wen L; Bottino R; Xiao X; Kilberg MS; Husain SZ
    Cell Mol Gastroenterol Hepatol; 2020; 9(1):1-13. PubMed ID: 31421261
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells.
    Nishikawa G; Kawada K; Hanada K; Maekawa H; Itatani Y; Miyoshi H; Taketo MM; Obama K
    Cells; 2022 Oct; 11(20):. PubMed ID: 36291140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression.
    Grima-Reyes M; Vandenberghe A; Nemazanyy I; Meola P; Paul R; Reverso-Meinietti J; Martinez-Turtos A; Nottet N; Chan WK; Lorenzi PL; Marchetti S; Ricci JE; Chiche J
    Sci Adv; 2022 Jul; 8(27):eabn6491. PubMed ID: 35857457
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Utility of
    Watanabe A; Miyake K; Yamada Y; Sunamura EI; Yotani T; Kagami K; Kasai S; Tamai M; Harama D; Akahane K; Goi K; Sakaguchi K; Goto H; Kitahara S; Inukai T
    Epigenetics; 2023 Dec; 18(1):2268814. PubMed ID: 37839090
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL.
    Akahane K; Kimura S; Miyake K; Watanabe A; Kagami K; Yoshimura K; Shinohara T; Harama D; Kasai S; Goi K; Kawai T; Hata K; Kiyokawa N; Koh K; Imamura T; Horibe K; Look AT; Minegishi M; Sugita K; Takita J; Inukai T
    Blood Adv; 2022 Jan; 6(1):212-224. PubMed ID: 34535013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bisabosqual A: A novel asparagine synthetase inhibitor suppressing the proliferation and migration of human non-small cell lung cancer A549 cells.
    Pan Y; Suzuki T; Sakai K; Hirano Y; Ikeda H; Hattori A; Dohmae N; Nishio K; Kakeya H
    Eur J Pharmacol; 2023 Dec; 960():176156. PubMed ID: 38059445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.
    Yu Q; Wang X; Wang L; Zheng J; Wang J; Wang B
    Scand J Gastroenterol; 2016 Oct; 51(10):1220-6. PubMed ID: 27251594
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.