140 related articles for article (PubMed ID: 23411396)
1. Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: nonradioactive counterparts of putative PET-compatible apoptosis imaging agents.
Limpachayaporn P; Schäfers M; Schober O; Kopka K; Haufe G
Bioorg Med Chem; 2013 Apr; 21(7):2025-36. PubMed ID: 23411396
[TBL] [Abstract][Full Text] [Related]
2. Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7.
Limpachayaporn P; Riemann B; Kopka K; Schober O; Schäfers M; Haufe G
Eur J Med Chem; 2013 Jun; 64():562-78. PubMed ID: 23685941
[TBL] [Abstract][Full Text] [Related]
3. Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis.
Podichetty AK; Wagner S; Schröer S; Faust A; Schäfers M; Schober O; Kopka K; Haufe G
J Med Chem; 2009 Jun; 52(11):3484-95. PubMed ID: 19445513
[TBL] [Abstract][Full Text] [Related]
4. 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis.
Kopka K; Faust A; Keul P; Wagner S; Breyholz HJ; Höltke C; Schober O; Schäfers M; Levkau B
J Med Chem; 2006 Nov; 49(23):6704-15. PubMed ID: 17154501
[TBL] [Abstract][Full Text] [Related]
5. The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent.
Faust A; Wagner S; Law MP; Hermann S; Schnöckel U; Keul P; Schober O; Schäfers M; Levkau B; Kopka K
Q J Nucl Med Mol Imaging; 2007 Mar; 51(1):67-73. PubMed ID: 17372575
[TBL] [Abstract][Full Text] [Related]
6. Fluorinated isatin derivatives. Part 3. New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors.
Podichetty AK; Wagner S; Faust A; Schäfers M; Schober O; Kopka K; Haufe G
Future Med Chem; 2009 Aug; 1(5):969-89. PubMed ID: 21426092
[TBL] [Abstract][Full Text] [Related]
7. Fluorinated isatin derivatives. Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors.
Podichetty AK; Faust A; Kopka K; Wagner S; Schober O; Schäfers M; Haufe G
Bioorg Med Chem; 2009 Apr; 17(7):2680-8. PubMed ID: 19299147
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography.
Limpachayaporn P; Wagner S; Kopka K; Hermann S; Schäfers M; Haufe G
J Med Chem; 2013 Jun; 56(11):4509-20. PubMed ID: 23656488
[TBL] [Abstract][Full Text] [Related]
9. Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging.
Limpachayaporn P; Schäfers M; Haufe G
Future Med Chem; 2015; 7(9):1173-96. PubMed ID: 26132525
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of 7-halogenated isatin sulfonamides: nonradioactive counterparts of caspase-3/-7 inhibitor-based potential radiopharmaceuticals for molecular imaging of apoptosis.
Limpachayaporn P; Wagner S; Kopka K; Schober O; Schäfers M; Haufe G
J Med Chem; 2014 Nov; 57(22):9383-95. PubMed ID: 25358116
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.
Zhou D; Chu W; Rothfuss J; Zeng C; Xu J; Jones L; Welch MJ; Mach RH
Bioorg Med Chem Lett; 2006 Oct; 16(19):5041-6. PubMed ID: 16891117
[TBL] [Abstract][Full Text] [Related]
12. Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis.
Waldmann CM; Hermann S; Faust A; Riemann B; Schober O; Schäfers M; Haufe G; Kopka K
Bioorg Med Chem; 2015 Sep; 23(17):5734-9. PubMed ID: 26210158
[TBL] [Abstract][Full Text] [Related]
13. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.
Chu W; Zhang J; Zeng C; Rothfuss J; Tu Z; Chu Y; Reichert DE; Welch MJ; Mach RH
J Med Chem; 2005 Dec; 48(24):7637-47. PubMed ID: 16302804
[TBL] [Abstract][Full Text] [Related]
14. Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors.
Firoozpour L; Gao L; Moghimi S; Pasalar P; Davoodi J; Wang MW; Rezaei Z; Dadgar A; Yahyavi H; Amanlou M; Foroumadi A
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1674-1684. PubMed ID: 32842789
[TBL] [Abstract][Full Text] [Related]
15. Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.
Chu W; Rothfuss J; d'Avignon A; Zeng C; Zhou D; Hotchkiss RS; Mach RH
J Med Chem; 2007 Jul; 50(15):3751-5. PubMed ID: 17585855
[TBL] [Abstract][Full Text] [Related]
16. In vitro cytotoxicity evaluation of some substituted isatin derivatives.
Vine KL; Locke JM; Ranson M; Benkendorff K; Pyne SG; Bremner JB
Bioorg Med Chem; 2007 Jan; 15(2):931-8. PubMed ID: 17088067
[TBL] [Abstract][Full Text] [Related]
17. A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury.
Chapman JG; Magee WP; Stukenbrok HA; Beckius GE; Milici AJ; Tracey WR
Eur J Pharmacol; 2002 Dec; 456(1-3):59-68. PubMed ID: 12450570
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and evaluation of N-acyl-substituted 1,2-benzisothiazol-3-one derivatives as caspase-3 inhibitors.
Li Z; Pan Y; Zhong W; Zhu Y; Zhao Y; Li L; Liu W; Zhou H; Yang C
Bioorg Med Chem; 2014 Dec; 22(24):6735-45. PubMed ID: 25468037
[TBL] [Abstract][Full Text] [Related]
19. Potent and selective nonpeptide inhibitors of caspases 3 and 7.
Lee D; Long SA; Murray JH; Adams JL; Nuttall ME; Nadeau DP; Kikly K; Winkler JD; Sung CM; Ryan MD; Levy MA; Keller PM; DeWolf WE
J Med Chem; 2001 Jun; 44(12):2015-26. PubMed ID: 11384246
[TBL] [Abstract][Full Text] [Related]
20. Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise.
Flütsch A; Ackermann R; Schroeder T; Lukarska M; Hausammann GJ; Weinert C; Briand C; Grütter MG
Biochem J; 2014 Jul; 461(2):279-90. PubMed ID: 24779913
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
