213 related articles for article (PubMed ID: 23411397)
1. Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis.
Mani T; Wang F; Knabe WE; Sinn AL; Khanna M; Jo I; Sandusky GE; Sledge GW; Jones DR; Khanna R; Pollok KE; Meroueh SO
Bioorg Med Chem; 2013 Apr; 21(7):2145-55. PubMed ID: 23411397
[TBL] [Abstract][Full Text] [Related]
2. Targeting multiple conformations leads to small molecule inhibitors of the uPAR·uPA protein-protein interaction that block cancer cell invasion.
Khanna M; Wang F; Jo I; Knabe WE; Wilson SM; Li L; Bum-Erdene K; Li J; W Sledge G; Khanna R; Meroueh SO
ACS Chem Biol; 2011 Nov; 6(11):1232-43. PubMed ID: 21875078
[TBL] [Abstract][Full Text] [Related]
3. A new class of orthosteric uPAR·uPA small-molecule antagonists are allosteric inhibitors of the uPAR·vitronectin interaction.
Liu D; Zhou D; Wang B; Knabe WE; Meroueh SO
ACS Chem Biol; 2015 Jun; 10(6):1521-34. PubMed ID: 25671694
[TBL] [Abstract][Full Text] [Related]
4. Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.
Wang F; Li J; Sinn AL; Knabe WE; Khanna M; Jo I; Silver JM; Oh K; Li L; Sandusky GE; Sledge GW; Nakshatri H; Jones DR; Pollok KE; Meroueh SO
J Med Chem; 2011 Oct; 54(20):7193-205. PubMed ID: 21851064
[TBL] [Abstract][Full Text] [Related]
5. Angiogenin interacts with the plasminogen activation system at the cell surface of breast cancer cells to regulate plasmin formation and cell migration.
Dutta S; Bandyopadhyay C; Bottero V; Veettil MV; Wilson L; Pins MR; Johnson KE; Warshall C; Chandran B
Mol Oncol; 2014 May; 8(3):483-507. PubMed ID: 24457100
[TBL] [Abstract][Full Text] [Related]
6. Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness.
Holst-Hansen C; Johannessen B; Høyer-Hansen G; Rømer J; Ellis V; Brünner N
Clin Exp Metastasis; 1996 May; 14(3):297-307. PubMed ID: 8674284
[TBL] [Abstract][Full Text] [Related]
7. CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.
Montgomery N; Hill A; McFarlane S; Neisen J; O'Grady A; Conlon S; Jirstrom K; Kay EW; Waugh DJ
Breast Cancer Res; 2012 May; 14(3):R84. PubMed ID: 22621373
[TBL] [Abstract][Full Text] [Related]
8. Calcitonin inhibits invasion of breast cancer cells: involvement of urokinase-type plasminogen activator (uPA) and uPA receptor.
Han B; Nakamura M; Zhou G; Ishii A; Nakamura A; Bai Y; Mori I; Kakudo K
Int J Oncol; 2006 Apr; 28(4):807-14. PubMed ID: 16525628
[TBL] [Abstract][Full Text] [Related]
9. Growth inhibition of MDA-MB-231 cell line by peptides designed based on uPA.
Tarighi P; Khorramizadeh M; Madadkar-Sobhani A; Ostad S; Ghahremani M
Acta Med Iran; 2015 Jul; 53(7):403-7. PubMed ID: 26520626
[TBL] [Abstract][Full Text] [Related]
10. Down-regulation of uPA and uPAR by 3,3'-diindolylmethane contributes to the inhibition of cell growth and migration of breast cancer cells.
Ahmad A; Kong D; Wang Z; Sarkar SH; Banerjee S; Sarkar FH
J Cell Biochem; 2009 Nov; 108(4):916-25. PubMed ID: 19693769
[TBL] [Abstract][Full Text] [Related]
11. Baicalin suppresses migration, invasion and metastasis of breast cancer via p38MAPK signaling pathway.
Wang XF; Zhou QM; Du J; Zhang H; Lu YY; Su SB
Anticancer Agents Med Chem; 2013 Jul; 13(6):923-31. PubMed ID: 23387975
[TBL] [Abstract][Full Text] [Related]
12. Evodiamine induces apoptosis and inhibits metastasis in MDA‑MB-231 human breast cancer cells in vitro and in vivo.
Du J; Wang XF; Zhou QM; Zhang TL; Lu YY; Zhang H; Su SB
Oncol Rep; 2013 Aug; 30(2):685-94. PubMed ID: 23708383
[TBL] [Abstract][Full Text] [Related]
13. Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428.
Xing RH; Mazar A; Henkin J; Rabbani SA
Cancer Res; 1997 Aug; 57(16):3585-93. PubMed ID: 9270032
[TBL] [Abstract][Full Text] [Related]
14. Small molecule antagonists of the urokinase (uPA): urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand.
De Souza M; Matthews H; Lee JA; Ranson M; Kelso MJ
Bioorg Med Chem; 2011 Apr; 19(8):2549-56. PubMed ID: 21454081
[TBL] [Abstract][Full Text] [Related]
15. Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK.
Luo J; Sun X; Gao F; Zhao X; Zhong B; Wang H; Sun Z
J Exp Clin Cancer Res; 2011 Jul; 30(1):71. PubMed ID: 21798065
[TBL] [Abstract][Full Text] [Related]
16. Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
Sun Y; Wang X; Zhou Q; Lu Y; Zhang H; Chen Q; Zhao M; Su S
Oncol Rep; 2015 Jan; 33(1):338-46. PubMed ID: 25370743
[TBL] [Abstract][Full Text] [Related]
17. Small-Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection.
Xu D; Bum-Erdene K; Leth JM; Ghozayel MK; Ploug M; Meroueh SO
ChemMedChem; 2021 Jan; 16(2):377-387. PubMed ID: 33107192
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.
Chia JS; Du JL; Hsu WB; Sun A; Chiang CP; Wang WB
BMC Cancer; 2010 Apr; 10():175. PubMed ID: 20429953
[TBL] [Abstract][Full Text] [Related]
19. Maspin regulates hypoxia-mediated stimulation of uPA/uPAR complex in invasive breast cancer cells.
Amir S; Margaryan NV; Odero-Marah V; Khalkhali-Ellis Z; Hendrix MJ
Cancer Biol Ther; 2005 Apr; 4(4):400-6. PubMed ID: 15846059
[TBL] [Abstract][Full Text] [Related]
20. [Mechanism of tumor cell-induced extracellular matrix degradation--inhibition of cell-surface proteolytic activity might have a therapeutic effect on tumor cell invasion and metastasis].
Kobayashi H
Nihon Sanka Fujinka Gakkai Zasshi; 1996 Aug; 48(8):623-32. PubMed ID: 8808830
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
