1399 related articles for article (PubMed ID: 23415312)
1. Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS.
Ash PE; Bieniek KF; Gendron TF; Caulfield T; Lin WL; Dejesus-Hernandez M; van Blitterswijk MM; Jansen-West K; Paul JW; Rademakers R; Boylan KB; Dickson DW; Petrucelli L
Neuron; 2013 Feb; 77(4):639-46. PubMed ID: 23415312
[TBL] [Abstract][Full Text] [Related]
2. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
Gendron TF; Bieniek KF; Zhang YJ; Jansen-West K; Ash PE; Caulfield T; Daughrity L; Dunmore JH; Castanedes-Casey M; Chew J; Cosio DM; van Blitterswijk M; Lee WC; Rademakers R; Boylan KB; Dickson DW; Petrucelli L
Acta Neuropathol; 2013 Dec; 126(6):829-44. PubMed ID: 24129584
[TBL] [Abstract][Full Text] [Related]
3. c9RAN translation: a potential therapeutic target for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia.
Gendron TF; Cosio DM; Petrucelli L
Expert Opin Ther Targets; 2013 Sep; 17(9):991-5. PubMed ID: 23844663
[TBL] [Abstract][Full Text] [Related]
4. Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72.
Murray ME; DeJesus-Hernandez M; Rutherford NJ; Baker M; Duara R; Graff-Radford NR; Wszolek ZK; Ferman TJ; Josephs KA; Boylan KB; Rademakers R; Dickson DW
Acta Neuropathol; 2011 Dec; 122(6):673-90. PubMed ID: 22083254
[TBL] [Abstract][Full Text] [Related]
5. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.
Zhang YJ; Jansen-West K; Xu YF; Gendron TF; Bieniek KF; Lin WL; Sasaguri H; Caulfield T; Hubbard J; Daughrity L; Chew J; Belzil VV; Prudencio M; Stankowski JN; Castanedes-Casey M; Whitelaw E; Ash PE; DeTure M; Rademakers R; Boylan KB; Dickson DW; Petrucelli L
Acta Neuropathol; 2014 Oct; 128(4):505-24. PubMed ID: 25173361
[TBL] [Abstract][Full Text] [Related]
6. Molecular Mechanisms of Neurodegeneration Related to
Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
[TBL] [Abstract][Full Text] [Related]
7. Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.
Yamakawa M; Ito D; Honda T; Kubo K; Noda M; Nakajima K; Suzuki N
Hum Mol Genet; 2015 Mar; 24(6):1630-45. PubMed ID: 25398948
[TBL] [Abstract][Full Text] [Related]
8. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Almeida S; Gascon E; Tran H; Chou HJ; Gendron TF; Degroot S; Tapper AR; Sellier C; Charlet-Berguerand N; Karydas A; Seeley WW; Boxer AL; Petrucelli L; Miller BL; Gao FB
Acta Neuropathol; 2013 Sep; 126(3):385-99. PubMed ID: 23836290
[TBL] [Abstract][Full Text] [Related]
9. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
DeJesus-Hernandez M; Mackenzie IR; Boeve BF; Boxer AL; Baker M; Rutherford NJ; Nicholson AM; Finch NA; Flynn H; Adamson J; Kouri N; Wojtas A; Sengdy P; Hsiung GY; Karydas A; Seeley WW; Josephs KA; Coppola G; Geschwind DH; Wszolek ZK; Feldman H; Knopman DS; Petersen RC; Miller BL; Dickson DW; Boylan KB; Graff-Radford NR; Rademakers R
Neuron; 2011 Oct; 72(2):245-56. PubMed ID: 21944778
[TBL] [Abstract][Full Text] [Related]
10. Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.
Todd TW; Petrucelli L
J Neurochem; 2016 Aug; 138 Suppl 1():145-62. PubMed ID: 27016280
[TBL] [Abstract][Full Text] [Related]
11. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
Wen X; Westergard T; Pasinelli P; Trotti D
Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540
[TBL] [Abstract][Full Text] [Related]
12. Characterization of a family with c9FTD/ALS associated with the GGGGCC repeat expansion in C9ORF72.
Savica R; Adeli A; Vemuri P; Knopman DS; Dejesus-Hernandez M; Rademakers R; Fields JA; Whitwell J; Jack CR; Lowe V; Petersen RC; Boeve BF
Arch Neurol; 2012 Sep; 69(9):1164-9. PubMed ID: 22637471
[TBL] [Abstract][Full Text] [Related]
13. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study.
Majounie E; Renton AE; Mok K; Dopper EG; Waite A; Rollinson S; Chiò A; Restagno G; Nicolaou N; Simon-Sanchez J; van Swieten JC; Abramzon Y; Johnson JO; Sendtner M; Pamphlett R; Orrell RW; Mead S; Sidle KC; Houlden H; Rohrer JD; Morrison KE; Pall H; Talbot K; Ansorge O; ; ; ; Hernandez DG; Arepalli S; Sabatelli M; Mora G; Corbo M; Giannini F; Calvo A; Englund E; Borghero G; Floris GL; Remes AM; Laaksovirta H; McCluskey L; Trojanowski JQ; Van Deerlin VM; Schellenberg GD; Nalls MA; Drory VE; Lu CS; Yeh TH; Ishiura H; Takahashi Y; Tsuji S; Le Ber I; Brice A; Drepper C; Williams N; Kirby J; Shaw P; Hardy J; Tienari PJ; Heutink P; Morris HR; Pickering-Brown S; Traynor BJ
Lancet Neurol; 2012 Apr; 11(4):323-30. PubMed ID: 22406228
[TBL] [Abstract][Full Text] [Related]
14. Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD.
Niblock M; Smith BN; Lee YB; Sardone V; Topp S; Troakes C; Al-Sarraj S; Leblond CS; Dion PA; Rouleau GA; Shaw CE; Gallo JM
Acta Neuropathol Commun; 2016 Feb; 4():18. PubMed ID: 26916632
[TBL] [Abstract][Full Text] [Related]
15. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
[TBL] [Abstract][Full Text] [Related]
16. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
Simón-Sánchez J; Dopper EG; Cohn-Hokke PE; Hukema RK; Nicolaou N; Seelaar H; de Graaf JR; de Koning I; van Schoor NM; Deeg DJ; Smits M; Raaphorst J; van den Berg LH; Schelhaas HJ; De Die-Smulders CE; Majoor-Krakauer D; Rozemuller AJ; Willemsen R; Pijnenburg YA; Heutink P; van Swieten JC
Brain; 2012 Mar; 135(Pt 3):723-35. PubMed ID: 22300876
[TBL] [Abstract][Full Text] [Related]
17. All in the Family: Repeats and ALS/FTD.
Pattamatta A; Cleary JD; Ranum LPW
Trends Neurosci; 2018 May; 41(5):247-250. PubMed ID: 29703376
[TBL] [Abstract][Full Text] [Related]
18. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.
Zu T; Liu Y; Bañez-Coronel M; Reid T; Pletnikova O; Lewis J; Miller TM; Harms MB; Falchook AE; Subramony SH; Ostrow LW; Rothstein JD; Troncoso JC; Ranum LP
Proc Natl Acad Sci U S A; 2013 Dec; 110(51):E4968-77. PubMed ID: 24248382
[TBL] [Abstract][Full Text] [Related]
19. Japanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF72.
Konno T; Shiga A; Tsujino A; Sugai A; Kato T; Kanai K; Yokoseki A; Eguchi H; Kuwabara S; Nishizawa M; Takahashi H; Onodera O
J Neurol Neurosurg Psychiatry; 2013 Apr; 84(4):398-401. PubMed ID: 23012445
[TBL] [Abstract][Full Text] [Related]
20. Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype.
Rutherford NJ; Heckman MG; Dejesus-Hernandez M; Baker MC; Soto-Ortolaza AI; Rayaprolu S; Stewart H; Finger E; Volkening K; Seeley WW; Hatanpaa KJ; Lomen-Hoerth C; Kertesz A; Bigio EH; Lippa C; Knopman DS; Kretzschmar HA; Neumann M; Caselli RJ; White CL; Mackenzie IR; Petersen RC; Strong MJ; Miller BL; Boeve BF; Uitti RJ; Boylan KB; Wszolek ZK; Graff-Radford NR; Dickson DW; Ross OA; Rademakers R
Neurobiol Aging; 2012 Dec; 33(12):2950.e5-7. PubMed ID: 22840558
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
