BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 23417678)

  • 1. Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.
    Hashimoto K; Otero M; Imagawa K; de Andrés MC; Coico JM; Roach HI; Oreffo ROC; Marcu KB; Goldring MB
    J Biol Chem; 2013 Apr; 288(14):10061-10072. PubMed ID: 23417678
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis.
    Imagawa K; de Andrés MC; Hashimoto K; Pitt D; Itoi E; Goldring MB; Roach HI; Oreffo RO
    Biochem Biophys Res Commun; 2011 Feb; 405(3):362-7. PubMed ID: 21219853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes.
    Hashimoto K; Oreffo RO; Gibson MB; Goldring MB; Roach HI
    Arthritis Rheum; 2009 Nov; 60(11):3303-13. PubMed ID: 19877066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes.
    Takahashi A; de Andrés MC; Hashimoto K; Itoi E; Otero M; Goldring MB; Oreffo ROC
    Sci Rep; 2017 Aug; 7(1):7771. PubMed ID: 28798419
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
    Otero M; Plumb DA; Tsuchimochi K; Dragomir CL; Hashimoto K; Peng H; Olivotto E; Bevilacqua M; Tan L; Yang Z; Zhan Y; Oettgen P; Li Y; Marcu KB; Goldring MB
    J Biol Chem; 2012 Jan; 287(5):3559-72. PubMed ID: 22158614
    [TBL] [Abstract][Full Text] [Related]  

  • 6. cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.
    Bui C; Barter MJ; Scott JL; Xu Y; Galler M; Reynard LN; Rowan AD; Young DA
    FASEB J; 2012 Jul; 26(7):3000-11. PubMed ID: 22505473
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation.
    Imagawa K; de Andrés MC; Hashimoto K; Itoi E; Otero M; Roach HI; Goldring MB; Oreffo RO
    Arthritis Rheumatol; 2014 Nov; 66(11):3040-51. PubMed ID: 25048791
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
    Hirata M; Kugimiya F; Fukai A; Saito T; Yano F; Ikeda T; Mabuchi A; Sapkota BR; Akune T; Nishida N; Yoshimura N; Nakagawa T; Tokunaga K; Nakamura K; Chung UI; Kawaguchi H
    Hum Mol Genet; 2012 Mar; 21(5):1111-23. PubMed ID: 22095691
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of interleukin 1-induced matrix metalloproteinase 13 expression in human chondrocytes by interferon gamma.
    Ahmad R; Qureshi HY; El Mabrouk M; Sylvester J; Ahmad M; Zafarullah M
    Ann Rheum Dis; 2007 Jun; 66(6):782-9. PubMed ID: 17179173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice.
    Ryu JH; Yang S; Shin Y; Rhee J; Chun CH; Chun JS
    Arthritis Rheum; 2011 Sep; 63(9):2732-43. PubMed ID: 21590680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.
    Roach HI; Yamada N; Cheung KS; Tilley S; Clarke NM; Oreffo RO; Kokubun S; Bronner F
    Arthritis Rheum; 2005 Oct; 52(10):3110-24. PubMed ID: 16200590
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes.
    Elayyan J; Lee EJ; Gabay O; Smith CA; Qiq O; Reich E; Mobasheri A; Henrotin Y; Kimber SJ; Dvir-Ginzberg M
    FASEB J; 2017 Jul; 31(7):3116-3125. PubMed ID: 28389425
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes.
    Macdonald CD; Falconer AMD; Chan CM; Wilkinson DJ; Skelton A; Reynard L; Litherland GJ; Europe-Finner GN; Rowan AD
    PLoS One; 2018; 13(11):e0207240. PubMed ID: 30440036
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.
    de Andrés MC; Imagawa K; Hashimoto K; Gonzalez A; Roach HI; Goldring MB; Oreffo RO
    Arthritis Rheum; 2013 Mar; 65(3):732-42. PubMed ID: 23239081
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD(+)-SIRT axis in articular chondrocytes is involved in osteoarthritis.
    Oh H; Kwak JS; Yang S; Gong MK; Kim JH; Rhee J; Kim SK; Kim HE; Ryu JH; Chun JS
    Osteoarthritis Cartilage; 2015 Dec; 23(12):2288-2296. PubMed ID: 26209889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cirsium japonicum var. maackii and apigenin block Hif-2α-induced osteoarthritic cartilage destruction.
    Cho C; Kang LJ; Jang D; Jeon J; Lee H; Choi S; Han SJ; Oh E; Nam J; Kim CS; Park E; Jeong SY; Park CH; Shin YS; Eyun SI; Yang S
    J Cell Mol Med; 2019 Aug; 23(8):5369-5379. PubMed ID: 31148341
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epigenetic regulation during fetal femur development: DNA methylation matters.
    de Andrés MC; Kingham E; Imagawa K; Gonzalez A; Roach HI; Wilson DI; Oreffo RO
    PLoS One; 2013; 8(1):e54957. PubMed ID: 23383012
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arthropod steroid hormone (20-Hydroxyecdysone) suppresses IL-1β-induced catabolic gene expression in cartilage.
    Sheu SY; Ho SR; Sun JS; Chen CY; Ke CJ
    BMC Complement Altern Med; 2015 Jan; 15():1. PubMed ID: 25617057
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MicroRNA-365 regulates IL-1β-induced catabolic factor expression by targeting HIF-2α in primary chondrocytes.
    Hwang HS; Park SJ; Lee MH; Kim HA
    Sci Rep; 2017 Dec; 7(1):17889. PubMed ID: 29263346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional regulation of the human reduced folate carrier in childhood acute lymphoblastic leukemia cells.
    Liu M; Ge Y; Payton SG; Aboukameel A; Buck S; Flatley RM; Haska C; Mohammad R; Taub JW; Matherly LH
    Clin Cancer Res; 2006 Jan; 12(2):608-16. PubMed ID: 16428507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.