BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 23420844)

  • 1. Glutamate acts as a partial inverse agonist to metabotropic glutamate receptor with a single amino acid mutation in the transmembrane domain.
    Yanagawa M; Yamashita T; Shichida Y
    J Biol Chem; 2013 Apr; 288(14):9593-9601. PubMed ID: 23420844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational change of the transmembrane helices II and IV of metabotropic glutamate receptor involved in G protein activation.
    Yamashita T; Terakita A; Kai T; Shichida Y
    J Neurochem; 2008 Jul; 106(2):850-9. PubMed ID: 18445134
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine.
    Malherbe P; Kratochwil N; Zenner MT; Piussi J; Diener C; Kratzeisen C; Fischer C; Porter RH
    Mol Pharmacol; 2003 Oct; 64(4):823-32. PubMed ID: 14500738
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative fluorescence resonance energy transfer analysis of metabotropic glutamate receptors: implications about the dimeric arrangement and rearrangement upon ligand bindings.
    Yanagawa M; Yamashita T; Shichida Y
    J Biol Chem; 2011 Jul; 286(26):22971-81. PubMed ID: 21550987
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular determinants of high affinity binding to group III metabotropic glutamate receptors.
    Rosemond E; Peltekova V; Naples M; Thøgersen H; Hampson DR
    J Biol Chem; 2002 Mar; 277(9):7333-40. PubMed ID: 11744707
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational rearrangement during activation of a metabotropic glutamate receptor.
    Liauw BW; Afsari HS; Vafabakhsh R
    Nat Chem Biol; 2021 Mar; 17(3):291-297. PubMed ID: 33398167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
    Thibado JK; Tano JY; Lee J; Salas-Estrada L; Provasi D; Strauss A; Marcelo Lamim Ribeiro J; Xiang G; Broichhagen J; Filizola M; Lohse MJ; Levitz J
    Elife; 2021 Apr; 10():. PubMed ID: 33880992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor.
    Jensen AA; Sheppard PO; Jensen LB; O'Hara PJ; Bräuner-Osborne H
    J Biol Chem; 2001 Mar; 276(13):10110-8. PubMed ID: 11133983
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.
    El Moustaine D; Granier S; Doumazane E; Scholler P; Rahmeh R; Bron P; Mouillac B; Banères JL; Rondard P; Pin JP
    Proc Natl Acad Sci U S A; 2012 Oct; 109(40):16342-7. PubMed ID: 22988116
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors.
    Doumazane E; Scholler P; Fabre L; Zwier JM; Trinquet E; Pin JP; Rondard P
    Proc Natl Acad Sci U S A; 2013 Apr; 110(15):E1416-25. PubMed ID: 23487753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A pivot between helices V and VI near the retinal-binding site is necessary for activation in rhodopsins.
    Tsukamoto H; Terakita A; Shichida Y
    J Biol Chem; 2010 Mar; 285(10):7351-7. PubMed ID: 20053991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.
    Zhang Y; Nayeem N; Nanao MH; Green T
    J Neurosci; 2006 Sep; 26(39):10033-42. PubMed ID: 17005866
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
    Bhattacharya S; Hall SE; Vaidehi N
    J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
    Brock C; Oueslati N; Soler S; Boudier L; Rondard P; Pin JP
    J Biol Chem; 2007 Nov; 282(45):33000-8. PubMed ID: 17855348
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.
    Litschig S; Gasparini F; Rueegg D; Stoehr N; Flor PJ; Vranesic I; Prézeau L; Pin JP; Thomsen C; Kuhn R
    Mol Pharmacol; 1999 Mar; 55(3):453-61. PubMed ID: 10051528
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual signaling is differentially activated by different active states of the metabotropic glutamate receptor 1alpha.
    Tateyama M; Kubo Y
    Proc Natl Acad Sci U S A; 2006 Jan; 103(4):1124-8. PubMed ID: 16410359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural organization and interactions of transmembrane domains in tetraspanin proteins.
    Kovalenko OV; Metcalf DG; DeGrado WF; Hemler ME
    BMC Struct Biol; 2005 Jun; 5():11. PubMed ID: 15985154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The second cytoplasmic loop of metabotropic glutamate receptor functions at the third loop position of rhodopsin.
    Yamashita T; Terakita A; Shichida Y
    J Biochem; 2001 Jul; 130(1):149-55. PubMed ID: 11432791
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.
    Worth CL; Kleinau G; Krause G
    PLoS One; 2009 Sep; 4(9):e7011. PubMed ID: 19756152
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel constitutively active mutation in the second cytoplasmic loop of metabotropic glutamate receptor.
    Yamashita T; Kai T; Terakita A; Shichida Y
    J Neurochem; 2004 Oct; 91(2):484-92. PubMed ID: 15447681
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.