BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 23423439)

  • 1. T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.
    Stirnweiss A; Hartig R; Gieseler S; Lindquist JA; Reichardt P; Philipsen L; Simeoni L; Poltorak M; Merten C; Zuschratter W; Prokazov Y; Paster W; Stockinger H; Harder T; Gunzer M; Schraven B
    Sci Signal; 2013 Feb; 6(263):ra13. PubMed ID: 23423439
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetically encoded Förster resonance energy transfer sensors for the conformation of the Src family kinase Lck.
    Paster W; Paar C; Eckerstorfer P; Jakober A; Drbal K; Schütz GJ; Sonnleitner A; Stockinger H
    J Immunol; 2009 Feb; 182(4):2160-7. PubMed ID: 19201869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.
    Philipsen L; Reddycherla AV; Hartig R; Gumz J; Kästle M; Kritikos A; Poltorak MP; Prokazov Y; Turbin E; Weber A; Zuschratter W; Schraven B; Simeoni L; Müller AJ
    Sci Signal; 2017 Jan; 10(462):. PubMed ID: 28096507
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56
    Kästle M; Merten C; Hartig R; Kaehne T; Liaunardy-Jopeace A; Woessner NM; Schamel WW; James J; Minguet S; Simeoni L; Schraven B
    Cell Commun Signal; 2020 Nov; 18(1):183. PubMed ID: 33225946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conformational states of the kinase Lck regulate clustering in early T cell signaling.
    Rossy J; Owen DM; Williamson DJ; Yang Z; Gaus K
    Nat Immunol; 2013 Jan; 14(1):82-9. PubMed ID: 23202272
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues.
    Nyakeriga AM; Garg H; Joshi A
    Cytometry A; 2012 Sep; 81(9):797-805. PubMed ID: 22674786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of protein kinase Ctheta function during T cell activation by Lck-mediated tyrosine phosphorylation.
    Liu Y; Witte S; Liu YC; Doyle M; Elly C; Altman A
    J Biol Chem; 2000 Feb; 275(5):3603-9. PubMed ID: 10652356
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biophysical basis underlying dynamic Lck activation visualized by ZapLck FRET biosensor.
    Wan R; Wu J; Ouyang M; Lei L; Wei J; Peng Q; Harrison R; Wu Y; Cheng B; Li K; Zhu C; Tang L; Wang Y; Lu S
    Sci Adv; 2019 Jun; 5(6):eaau2001. PubMed ID: 31223643
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TAOK3 Regulates Canonical TCR Signaling by Preventing Early SHP-1-Mediated Inactivation of LCK.
    Ormonde JVS; Li Z; Stegen C; Madrenas J
    J Immunol; 2018 Dec; 201(11):3431-3442. PubMed ID: 30373850
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and Characterization of the Amphioxus Lck and Its Associated Tyrosine Phosphorylation-Dependent Inhibitory LRR Receptor.
    Zhou J; Xiao Z; Zhan Y; Qu X; Mou S; Deng C; Zhang T; Lan X; Huang S; Li Y
    Front Immunol; 2021; 12():656366. PubMed ID: 34149695
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.
    Denny MF; Kaufman HC; Chan AC; Straus DB
    J Biol Chem; 1999 Feb; 274(8):5146-52. PubMed ID: 9988764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lck Inhibits Heat Shock Protein 65-Mediated Reverse Cholesterol Transport in T Cells.
    Luo T; Hu J; Xi D; Xiong H; He W; Liu J; Li M; Lu H; Zhao J; Lai W; Guo Z
    J Immunol; 2016 Nov; 197(10):3861-3870. PubMed ID: 27742830
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Negative regulation of Lck by Cbl ubiquitin ligase.
    Rao N; Miyake S; Reddi AL; Douillard P; Ghosh AK; Dodge IL; Zhou P; Fernandes ND; Band H
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3794-9. PubMed ID: 11904433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of competing mechanisms on Lck regulation.
    Bozso SJ; Kang JJH; Nagendran J
    Immunol Res; 2020 Oct; 68(5):289-295. PubMed ID: 32794043
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model.
    Ballek O; Valečka J; Manning J; Filipp D
    Immunol Cell Biol; 2015 Apr; 93(4):384-95. PubMed ID: 25420722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation.
    Choi YB; Son M; Park M; Shin J; Yun Y
    J Biol Chem; 2010 Mar; 285(10):7271-80. PubMed ID: 20007709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.
    Granum S; Sundvold-Gjerstad V; Gopalakrishnan RP; Berge T; Koll L; Abrahamsen G; Sørlie M; Spurkland A
    Sci Signal; 2014 Dec; 7(355):ra118. PubMed ID: 25492967
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner.
    Won J; Hur YG; Hur EM; Park SH; Kang MA; Choi Y; Park C; Lee KH; Yun Y
    Eur J Immunol; 2003 Apr; 33(4):870-9. PubMed ID: 12672052
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells.
    Vang T; Abrahamsen H; Myklebust S; Enserink J; Prydz H; Mustelin T; Amarzguioui M; Tasken K
    Eur J Immunol; 2004 Aug; 34(8):2191-9. PubMed ID: 15259016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipid raft assembly and Lck recruitment in TRAIL costimulation mediates NF-κB activation and T cell proliferation.
    Huang SC; Tsai HF; Tzeng HT; Liao HJ; Hsu PN
    J Immunol; 2011 Jan; 186(2):931-9. PubMed ID: 21160038
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.