BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 23428873)

  • 21. DOT1L-mediated H3K79me2 modification critically regulates gene expression during cardiomyocyte differentiation.
    Cattaneo P; Kunderfranco P; Greco C; Guffanti A; Stirparo GG; Rusconi F; Rizzi R; Di Pasquale E; Locatelli SL; Latronico MV; Bearzi C; Papait R; Condorelli G
    Cell Death Differ; 2016 Apr; 23(4):555-64. PubMed ID: 25526092
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.
    Kuntimaddi A; Achille NJ; Thorpe J; Lokken AA; Singh R; Hemenway CS; Adli M; Zeleznik-Le NJ; Bushweller JH
    Cell Rep; 2015 May; 11(5):808-20. PubMed ID: 25921540
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
    Deshpande AJ; Chen L; Fazio M; Sinha AU; Bernt KM; Banka D; Dias S; Chang J; Olhava EJ; Daigle SR; Richon VM; Pollock RM; Armstrong SA
    Blood; 2013 Mar; 121(13):2533-41. PubMed ID: 23361907
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
    Rau RE; Rodriguez BA; Luo M; Jeong M; Rosen A; Rogers JH; Campbell CT; Daigle SR; Deng L; Song Y; Sweet S; Chevassut T; Andreeff M; Kornblau SM; Li W; Goodell MA
    Blood; 2016 Aug; 128(7):971-81. PubMed ID: 27335278
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.
    Lin H; Cossu IG; Leu NA; Deshpande AJ; Bernt KM; Luo M; Wang PJ
    Development; 2023 May; 150(9):. PubMed ID: 37082953
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.
    Vlaming H; McLean CM; Korthout T; Alemdehy MF; Hendriks S; Lancini C; Palit S; Klarenbeek S; Kwesi-Maliepaard EM; Molenaar TM; Hoekman L; Schmidlin TT; Altelaar AM; van Welsem T; Dannenberg JH; Jacobs H; van Leeuwen F
    EMBO J; 2019 Jul; 38(14):e101564. PubMed ID: 31304633
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia.
    Oittinen M; Popp A; Kurppa K; Lindfors K; Mäki M; Kaikkonen MU; Viiri K
    Stem Cells; 2017 Feb; 35(2):445-457. PubMed ID: 27570105
    [TBL] [Abstract][Full Text] [Related]  

  • 28. H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
    Krivtsov AV; Feng Z; Lemieux ME; Faber J; Vempati S; Sinha AU; Xia X; Jesneck J; Bracken AP; Silverman LB; Kutok JL; Kung AL; Armstrong SA
    Cancer Cell; 2008 Nov; 14(5):355-68. PubMed ID: 18977325
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The diverse functions of Dot1 and H3K79 methylation.
    Nguyen AT; Zhang Y
    Genes Dev; 2011 Jul; 25(13):1345-58. PubMed ID: 21724828
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer.
    Zhang X; Liu D; Li M; Cao C; Wan D; Xi B; Li W; Tan J; Wang J; Wu Z; Ma D; Gao Q
    J Hematol Oncol; 2017 Jan; 10(1):29. PubMed ID: 28114995
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cryosectioning the intestinal crypt-villus axis: an ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells.
    Vincent A; Kazmierczak C; Duchêne B; Jonckheere N; Leteurtre E; Van Seuningen I
    Stem Cell Res; 2015 Jan; 14(1):105-13. PubMed ID: 25590428
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle.
    Fu H; Maunakea AK; Martin MM; Huang L; Zhang Y; Ryan M; Kim R; Lin CM; Zhao K; Aladjem MI
    PLoS Genet; 2013 Jun; 9(6):e1003542. PubMed ID: 23754963
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DOT1L and H3K79 Methylation in Transcription and Genomic Stability.
    Wood K; Tellier M; Murphy S
    Biomolecules; 2018 Feb; 8(1):. PubMed ID: 29495487
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Chromatin-modifying enzymes as modulators of reprogramming.
    Onder TT; Kara N; Cherry A; Sinha AU; Zhu N; Bernt KM; Cahan P; Marcarci BO; Unternaehrer J; Gupta PB; Lander ES; Armstrong SA; Daley GQ
    Nature; 2012 Mar; 483(7391):598-602. PubMed ID: 22388813
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Neuronal Dot1l Activity Acts as a Mitochondrial Gene-Repressor Associated with Human Brain Aging via H3K79 Hypermethylation.
    Van Heesbeen HJ; Von Oerthel L; De Vries PM; Wagemans CMRJ; Smidt MP
    Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36674903
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages.
    Chen X; Liu X; Zhang Y; Huai W; Zhou Q; Xu S; Chen X; Li N; Cao X
    Cell Mol Immunol; 2020 Jan; 17(1):76-84. PubMed ID: 30275539
    [TBL] [Abstract][Full Text] [Related]  

  • 37. DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
    Nguyen AT; Taranova O; He J; Zhang Y
    Blood; 2011 Jun; 117(25):6912-22. PubMed ID: 21521783
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.
    Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T
    Cancer Res; 2017 May; 77(9):2522-2533. PubMed ID: 28209620
    [TBL] [Abstract][Full Text] [Related]  

  • 39. H3K79 methylation directly precedes the histone-to-protamine transition in mammalian spermatids and is sensitive to bacterial infections.
    Dottermusch-Heidel C; Klaus ES; Gonzalez NH; Bhushan S; Meinhardt A; Bergmann M; Renkawitz-Pohl R; Rathke C; Steger K
    Andrology; 2014 Sep; 2(5):655-65. PubMed ID: 25079683
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The emerging roles of DOT1L in leukemia and normal development.
    McLean CM; Karemaker ID; van Leeuwen F
    Leukemia; 2014 Nov; 28(11):2131-8. PubMed ID: 24854991
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.