187 related articles for article (PubMed ID: 23429889)
1. Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.
Iusuf D; van Esch A; Hobbs M; Taylor M; Kenworthy KE; van de Steeg E; Wagenaar E; Schinkel AH
Mol Pharmacol; 2013 May; 83(5):919-29. PubMed ID: 23429889
[TBL] [Abstract][Full Text] [Related]
2. Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.
Iusuf D; Sparidans RW; van Esch A; Hobbs M; Kenworthy KE; van de Steeg E; Wagenaar E; Beijnen JH; Schinkel AH
Mol Pharm; 2012 Sep; 9(9):2497-504. PubMed ID: 22812517
[TBL] [Abstract][Full Text] [Related]
3. Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.
Iusuf D; Hendrikx JJ; van Esch A; van de Steeg E; Wagenaar E; Rosing H; Beijnen JH; Schinkel AH
Int J Cancer; 2015 Jan; 136(1):225-33. PubMed ID: 24825069
[TBL] [Abstract][Full Text] [Related]
4. In vivo disposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters.
Durmus S; Naik J; Buil L; Wagenaar E; van Tellingen O; Schinkel AH
Int J Cancer; 2014 Oct; 135(7):1700-10. PubMed ID: 24554572
[TBL] [Abstract][Full Text] [Related]
5. Enterohepatic disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine and gemfibrozil.
Bergman E; Lundahl A; Fridblom P; Hedeland M; Bondesson U; Knutson L; Lennernäs H
Drug Metab Dispos; 2009 Dec; 37(12):2349-58. PubMed ID: 19773540
[TBL] [Abstract][Full Text] [Related]
6. OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.
Iusuf D; Ludwig M; Elbatsh A; van Esch A; van de Steeg E; Wagenaar E; van der Valk M; Lin F; van Tellingen O; Schinkel AH
Mol Cancer Ther; 2014 Feb; 13(2):492-503. PubMed ID: 24194565
[TBL] [Abstract][Full Text] [Related]
7. Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.
Higgins JW; Bao JQ; Ke AB; Manro JR; Fallon JK; Smith PC; Zamek-Gliszczynski MJ
Drug Metab Dispos; 2014 Jan; 42(1):182-92. PubMed ID: 24194513
[TBL] [Abstract][Full Text] [Related]
8. The effect of gemfibrozil on the pharmacokinetics of rosuvastatin.
Schneck DW; Birmingham BK; Zalikowski JA; Mitchell PD; Wang Y; Martin PD; Lasseter KC; Brown CD; Windass AS; Raza A
Clin Pharmacol Ther; 2004 May; 75(5):455-63. PubMed ID: 15116058
[TBL] [Abstract][Full Text] [Related]
9. Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine.
Simonson SG; Raza A; Martin PD; Mitchell PD; Jarcho JA; Brown CD; Windass AS; Schneck DW
Clin Pharmacol Ther; 2004 Aug; 76(2):167-77. PubMed ID: 15289793
[TBL] [Abstract][Full Text] [Related]
10. Understanding the interplay of drug transporters involved in the disposition of rosuvastatin in the isolated perfused rat liver using a physiologically-based pharmacokinetic model.
Hobbs M; Parker C; Birch H; Kenworthy K
Xenobiotica; 2012 Apr; 42(4):327-38. PubMed ID: 22035568
[TBL] [Abstract][Full Text] [Related]
11. The effect of acute administration of rifampicin and imatinib on the enterohepatic transport of rosuvastatin in vivo.
Bergman E; Hedeland M; Bondesson U; Lennernäs H
Xenobiotica; 2010 Aug; 40(8):558-68. PubMed ID: 20583894
[TBL] [Abstract][Full Text] [Related]
12. Functions of OATP1A and 1B transporters in vivo: insights from mouse models.
Iusuf D; van de Steeg E; Schinkel AH
Trends Pharmacol Sci; 2012 Feb; 33(2):100-8. PubMed ID: 22130008
[TBL] [Abstract][Full Text] [Related]
13. Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin.
Prueksaritanont T; Chu X; Evers R; Klopfer SO; Caro L; Kothare PA; Dempsey C; Rasmussen S; Houle R; Chan G; Cai X; Valesky R; Fraser IP; Stoch SA
Br J Clin Pharmacol; 2014 Sep; 78(3):587-98. PubMed ID: 24617605
[TBL] [Abstract][Full Text] [Related]
14. Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin.
Kitamura S; Maeda K; Wang Y; Sugiyama Y
Drug Metab Dispos; 2008 Oct; 36(10):2014-23. PubMed ID: 18617601
[TBL] [Abstract][Full Text] [Related]
15. Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.
Bosgra S; van de Steeg E; Vlaming ML; Verhoeckx KC; Huisman MT; Verwei M; Wortelboer HM
Eur J Pharm Sci; 2014 Dec; 65():156-66. PubMed ID: 25261337
[TBL] [Abstract][Full Text] [Related]
16. Disposition of atorvastatin, rosuvastatin, and simvastatin in oatp1b2-/- mice and intraindividual variability in human subjects.
DeGorter MK; Urquhart BL; Gradhand U; Tirona RG; Kim RB
J Clin Pharmacol; 2012 Nov; 52(11):1689-97. PubMed ID: 22167570
[TBL] [Abstract][Full Text] [Related]
17. Eltrombopag increases plasma rosuvastatin exposure in healthy volunteers.
Allred AJ; Bowen CJ; Park JW; Peng B; Williams DD; Wire MB; Lee E
Br J Clin Pharmacol; 2011 Aug; 72(2):321-9. PubMed ID: 21434975
[TBL] [Abstract][Full Text] [Related]
18. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
Ho RH; Tirona RG; Leake BF; Glaeser H; Lee W; Lemke CJ; Wang Y; Kim RB
Gastroenterology; 2006 May; 130(6):1793-806. PubMed ID: 16697742
[TBL] [Abstract][Full Text] [Related]
19. Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1.
Higgins JW; Ke AB; Zamek-Gliszczynski MJ
Drug Metab Dispos; 2014 Nov; 42(11):1780-4. PubMed ID: 25106415
[TBL] [Abstract][Full Text] [Related]
20. The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin.
Windass AS; Lowes S; Wang Y; Brown CD
J Pharmacol Exp Ther; 2007 Sep; 322(3):1221-7. PubMed ID: 17585018
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
