188 related articles for article (PubMed ID: 23434821)
1. HCM-linked ∆160E cardiac troponin T mutation causes unique progressive structural and molecular ventricular remodeling in transgenic mice.
Moore RK; Grinspan LT; Jimenez J; Guinto PJ; Ertz-Berger B; Tardiff JC
J Mol Cell Cardiol; 2013 May; 58():188-98. PubMed ID: 23434821
[TBL] [Abstract][Full Text] [Related]
2. Independent FHC-related cardiac troponin T mutations exhibit specific alterations in myocellular contractility and calcium kinetics.
Haim TE; Dowell C; Diamanti T; Scheuer J; Tardiff JC
J Mol Cell Cardiol; 2007 Jun; 42(6):1098-110. PubMed ID: 17490679
[TBL] [Abstract][Full Text] [Related]
3. Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy.
Moore RK; Abdullah S; Tardiff JC
Arch Biochem Biophys; 2014 Jun; 552-553():21-8. PubMed ID: 24480310
[TBL] [Abstract][Full Text] [Related]
4. FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation.
Abdullah S; Lynn ML; McConnell MT; Klass MM; Baldo AP; Schwartz SD; Tardiff JC
J Biol Chem; 2019 Oct; 294(40):14634-14647. PubMed ID: 31387947
[TBL] [Abstract][Full Text] [Related]
5. Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.
Crocini C; Ferrantini C; Scardigli M; Coppini R; Mazzoni L; Lazzeri E; Pioner JM; Scellini B; Guo A; Song LS; Yan P; Loew LM; Tardiff J; Tesi C; Vanzi F; Cerbai E; Pavone FS; Sacconi L; Poggesi C
J Mol Cell Cardiol; 2016 Feb; 91():42-51. PubMed ID: 26714042
[TBL] [Abstract][Full Text] [Related]
6. Chronic Calmodulin-Kinase II Activation Drives Disease Progression in Mutation-Specific Hypertrophic Cardiomyopathy.
Lehman SJ; Tal-Grinspan L; Lynn ML; Strom J; Benitez GE; Anderson ME; Tardiff JC
Circulation; 2019 Mar; 139(12):1517-1529. PubMed ID: 30586744
[TBL] [Abstract][Full Text] [Related]
7. Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.
Ferrantini C; Coppini R; Pioner JM; Gentile F; Tosi B; Mazzoni L; Scellini B; Piroddi N; Laurino A; Santini L; Spinelli V; Sacconi L; De Tombe P; Moore R; Tardiff J; Mugelli A; Olivotto I; Cerbai E; Tesi C; Poggesi C
J Am Heart Assoc; 2017 Jul; 6(7):. PubMed ID: 28735292
[TBL] [Abstract][Full Text] [Related]
8. Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models.
Guinto PJ; Haim TE; Dowell-Martino CC; Sibinga N; Tardiff JC
Am J Physiol Heart Circ Physiol; 2009 Aug; 297(2):H614-26. PubMed ID: 19502551
[TBL] [Abstract][Full Text] [Related]
9. Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias.
Frey N; Franz WM; Gloeckner K; Degenhardt M; Müller M; Müller O; Merz H; Katus HA
Cardiovasc Res; 2000 Aug; 47(2):254-64. PubMed ID: 10946062
[TBL] [Abstract][Full Text] [Related]
10. Hypertrophic cardiomyopathy mutations increase myofilament Ca
Robinson P; Liu X; Sparrow A; Patel S; Zhang YH; Casadei B; Watkins H; Redwood C
J Biol Chem; 2018 Jul; 293(27):10487-10499. PubMed ID: 29760186
[TBL] [Abstract][Full Text] [Related]
11. Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies.
Lombardi R; Bell A; Senthil V; Sidhu J; Noseda M; Roberts R; Marian AJ
Cardiovasc Res; 2008 Jul; 79(1):109-17. PubMed ID: 18349139
[TBL] [Abstract][Full Text] [Related]
12. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
Sequeira V; Wijnker PJ; Nijenkamp LL; Kuster DW; Najafi A; Witjas-Paalberends ER; Regan JA; Boontje N; Ten Cate FJ; Germans T; Carrier L; Sadayappan S; van Slegtenhorst MA; Zaremba R; Foster DB; Murphy AM; Poggesi C; Dos Remedios C; Stienen GJ; Ho CY; Michels M; van der Velden J
Circ Res; 2013 May; 112(11):1491-505. PubMed ID: 23508784
[TBL] [Abstract][Full Text] [Related]
13. Induction and reversal of cardiac phenotype of human hypertrophic cardiomyopathy mutation cardiac troponin T-Q92 in switch on-switch off bigenic mice.
Lutucuta S; Tsybouleva N; Ishiyama M; Defreitas G; Wei L; Carabello B; Marian AJ
J Am Coll Cardiol; 2004 Dec; 44(11):2221-30. PubMed ID: 15582321
[TBL] [Abstract][Full Text] [Related]
14. Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca
Robinson P; Sparrow AJ; Patel S; Malinowska M; Reilly SN; Zhang YH; Casadei B; Watkins H; Redwood C
Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H306-H319. PubMed ID: 32618513
[TBL] [Abstract][Full Text] [Related]
15. Expression of a mutant (Arg92Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocyte contractility.
Marian AJ; Zhao G; Seta Y; Roberts R; Yu QT
Circ Res; 1997 Jul; 81(1):76-85. PubMed ID: 9201030
[TBL] [Abstract][Full Text] [Related]
16. Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca
Sparrow AJ; Watkins H; Daniels MJ; Redwood C; Robinson P
Am J Physiol Heart Circ Physiol; 2020 Mar; 318(3):H715-H722. PubMed ID: 32083971
[TBL] [Abstract][Full Text] [Related]
17. Dominant-negative effect of a mutant cardiac troponin T on cardiac structure and function in transgenic mice.
Oberst L; Zhao G; Park JT; Brugada R; Michael LH; Entman ML; Roberts R; Marian AJ
J Clin Invest; 1998 Oct; 102(8):1498-505. PubMed ID: 9788962
[TBL] [Abstract][Full Text] [Related]
18. Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy.
Tardiff JC; Hewett TE; Palmer BM; Olsson C; Factor SM; Moore RL; Robbins J; Leinwand LA
J Clin Invest; 1999 Aug; 104(4):469-81. PubMed ID: 10449439
[TBL] [Abstract][Full Text] [Related]
19. Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT.
Manning EP; Tardiff JC; Schwartz SD
J Mol Biol; 2012 Aug; 421(1):54-66. PubMed ID: 22579624
[TBL] [Abstract][Full Text] [Related]
20. Abnormal heart rate regulation in murine hearts with familial hypertrophic cardiomyopathy-related cardiac troponin T mutations.
Jimenez J; Tardiff JC
Am J Physiol Heart Circ Physiol; 2011 Feb; 300(2):H627-35. PubMed ID: 21131475
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]