375 related articles for article (PubMed ID: 23449980)
1. Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).
Ahn KH; Mahmoud MM; Shim JY; Kendall DA
J Biol Chem; 2013 Apr; 288(14):9790-9800. PubMed ID: 23449980
[TBL] [Abstract][Full Text] [Related]
2. Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.
Ahn KH; Mahmoud MM; Kendall DA
J Biol Chem; 2012 Apr; 287(15):12070-82. PubMed ID: 22343625
[TBL] [Abstract][Full Text] [Related]
3. Pyrimidinyl Biphenylureas Act as Allosteric Modulators to Activate Cannabinoid Receptor 1 and Initiate
Jagla CAD; Scott CE; Tang Y; Qiao C; Mateo-Semidey GE; Yudowski GA; Lu D; Kendall DA
Mol Pharmacol; 2019 Jan; 95(1):1-10. PubMed ID: 30322873
[TBL] [Abstract][Full Text] [Related]
4. Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.
Shore DM; Baillie GL; Hurst DH; Navas F; Seltzman HH; Marcu JP; Abood ME; Ross RA; Reggio PH
J Biol Chem; 2014 Feb; 289(9):5828-45. PubMed ID: 24366865
[TBL] [Abstract][Full Text] [Related]
5. Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.
Laprairie RB; Kulkarni AR; Kulkarni PM; Hurst DP; Lynch D; Reggio PH; Janero DR; Pertwee RG; Stevenson LA; Kelly ME; Denovan-Wright EM; Thakur GA
ACS Chem Neurosci; 2016 Jun; 7(6):776-98. PubMed ID: 27046127
[TBL] [Abstract][Full Text] [Related]
6. CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.
Baillie GL; Horswill JG; Anavi-Goffer S; Reggio PH; Bolognini D; Abood ME; McAllister S; Strange PG; Stephens GJ; Pertwee RG; Ross RA
Mol Pharmacol; 2013 Feb; 83(2):322-38. PubMed ID: 23160940
[TBL] [Abstract][Full Text] [Related]
7. Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action.
Cawston EE; Redmond WJ; Breen CM; Grimsey NL; Connor M; Glass M
Br J Pharmacol; 2013 Oct; 170(4):893-907. PubMed ID: 23937487
[TBL] [Abstract][Full Text] [Related]
8. Negative allosteric modulators of cannabinoid receptor 1: Ternary complexes including CB1, orthosteric CP55940 and allosteric ORG27569.
Aderibigbe AO; Pandey P; Doerksen RJ
J Biomol Struct Dyn; 2022 Aug; 40(13):5729-5747. PubMed ID: 33480332
[TBL] [Abstract][Full Text] [Related]
9. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.
Shenoy SK; Drake MT; Nelson CD; Houtz DA; Xiao K; Madabushi S; Reiter E; Premont RT; Lichtarge O; Lefkowitz RJ
J Biol Chem; 2006 Jan; 281(2):1261-73. PubMed ID: 16280323
[TBL] [Abstract][Full Text] [Related]
10. Assessing Allosteric Modulation of CB
Scott CE; Kendall DA
Methods Enzymol; 2017; 593():317-342. PubMed ID: 28750809
[TBL] [Abstract][Full Text] [Related]
11. Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor.
Khajehali E; Malone DT; Glass M; Sexton PM; Christopoulos A; Leach K
Mol Pharmacol; 2015 Aug; 88(2):368-79. PubMed ID: 26044547
[TBL] [Abstract][Full Text] [Related]
12. Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.
Gesty-Palmer D; Chen M; Reiter E; Ahn S; Nelson CD; Wang S; Eckhardt AE; Cowan CL; Spurney RF; Luttrell LM; Lefkowitz RJ
J Biol Chem; 2006 Apr; 281(16):10856-64. PubMed ID: 16492667
[TBL] [Abstract][Full Text] [Related]
13. GPCR kinase subtype requirements for arrestin-2 and -3 translocation to the cannabinoid CB
Manning JJ; Finlay DB; Glass M
Biochem Pharmacol; 2024 Jun; 224():116190. PubMed ID: 38604257
[TBL] [Abstract][Full Text] [Related]
14. A kinetic model for positive allosteric modulator (PAM)-antagonists for the type 1 cannabinoid (CB
Yang L; Zhu X; Finlay DB; Green H; Glass M; Duffull SB
Br J Pharmacol; 2023 Oct; 180(20):2661-2676. PubMed ID: 37277184
[TBL] [Abstract][Full Text] [Related]
15. Characterization of structurally novel G protein biased CB
Ford BM; Franks LN; Tai S; Fantegrossi WE; Stahl EL; Berquist MD; Cabanlong CV; Wilson CD; Penthala NR; Crooks PA; Prather PL
Pharmacol Res; 2017 Nov; 125(Pt B):161-177. PubMed ID: 28838808
[TBL] [Abstract][Full Text] [Related]
16. Parameterization of Org27569: an allosteric modulator of the cannabinoid CB1 G protein-coupled receptor.
Iliff HA; Lynch DL; Kotsikorou E; Reggio PH
J Comput Chem; 2011 Jul; 32(10):2119-26. PubMed ID: 21523790
[TBL] [Abstract][Full Text] [Related]
17. Allosteric modulators restore orthosteric agonist binding to mutated CB
Dopart R; Kendall DA
J Pharm Pharmacol; 2020 Jan; 72(1):84-91. PubMed ID: 31722122
[TBL] [Abstract][Full Text] [Related]
18. Cannabinoid 1 (CB
Manning JJ; Rawcliffe G; Finlay DB; Glass M
Br J Pharmacol; 2023 Feb; 180(3):369-382. PubMed ID: 36250246
[TBL] [Abstract][Full Text] [Related]
19. Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase.
Mahavadi S; Sriwai W; Huang J; Grider JR; Murthy KS
Am J Physiol Gastrointest Liver Physiol; 2014 Mar; 306(6):G535-45. PubMed ID: 24407588
[TBL] [Abstract][Full Text] [Related]
20. Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2.
Wei H; Ahn S; Barnes WG; Lefkowitz RJ
J Biol Chem; 2004 Nov; 279(46):48255-61. PubMed ID: 15355986
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]