BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 23451083)

  • 1. Telmisartan inhibits cell proliferation by blocking nuclear translocation of ProHB-EGF C-terminal fragment in colon cancer cells.
    Ozeki K; Tanida S; Morimoto C; Inoue Y; Mizoshita T; Tsukamoto H; Shimura T; Kataoka H; Kamiya T; Nishiwaki E; Ishiguro H; Higashiyama S; Joh T
    PLoS One; 2013; 8(2):e56770. PubMed ID: 23451083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of proHB-EGF carboxy-terminal fragment nuclear translocation: a new molecular target therapy for gastric cancer.
    Shimura T; Kataoka H; Ogasawara N; Kubota E; Sasaki M; Tanida S; Joh T
    Clin Cancer Res; 2008 Jun; 14(12):3956-65. PubMed ID: 18559618
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TGFβ induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells.
    Ebi M; Kataoka H; Shimura T; Kubota E; Hirata Y; Mizushima T; Mizoshita T; Tanaka M; Mabuchi M; Tsukamoto H; Tanida S; Kamiya T; Higashiyama S; Joh T
    Biochem Biophys Res Commun; 2010 Nov; 402(3):449-54. PubMed ID: 20934403
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion.
    Shimura T; Yoshida M; Fukuda S; Ebi M; Hirata Y; Mizoshita T; Tanida S; Kataoka H; Kamiya T; Higashiyama S; Joh T
    BMC Cancer; 2012 May; 12():205. PubMed ID: 22646534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF.
    Nanba D; Mammoto A; Hashimoto K; Higashiyama S
    J Cell Biol; 2003 Nov; 163(3):489-502. PubMed ID: 14597771
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle.
    Toki F; Nanba D; Matsuura N; Higashiyama S
    J Cell Physiol; 2005 Mar; 202(3):839-48. PubMed ID: 15389565
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The carboxyl-terminal fragment of pro-HB-EGF reverses Bcl6-mediated gene repression.
    Kinugasa Y; Hieda M; Hori M; Higashiyama S
    J Biol Chem; 2007 May; 282(20):14797-806. PubMed ID: 17392284
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane.
    Hieda M; Isokane M; Koizumi M; Higashi C; Tachibana T; Shudou M; Taguchi T; Hieda Y; Higashiyama S
    J Cell Biol; 2008 Feb; 180(4):763-9. PubMed ID: 18299347
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intranuclear translocation signaling of HB-EGF carboxy-terminal fragment and mucosal defense through cell proliferation and migration in digestive tracts.
    Tanida S; Kataoka H; Mizoshita T; Shimura T; Kamiya T; Joh T
    Digestion; 2010; 82(3):145-9. PubMed ID: 20588025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
    Goishi K; Higashiyama S; Klagsbrun M; Nakano N; Umata T; Ishikawa M; Mekada E; Taniguchi N
    Mol Biol Cell; 1995 Aug; 6(8):967-80. PubMed ID: 7579712
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heparin-binding epidermal growth factor-like growth factor isoforms and epidermal growth factor receptor/ErbB1 expression in bladder cancer and their relation to clinical outcome.
    Kramer C; Klasmeyer K; Bojar H; Schulz WA; Ackermann R; Grimm MO
    Cancer; 2007 May; 109(10):2016-24. PubMed ID: 17394193
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The cytoplasmic tail of heparin-binding EGF-like growth factor regulates bidirectional intracellular trafficking between the plasma membrane and ER.
    Hieda M; Koizumi M; Higashi C; Tachibana T; Taguchi T; Higashiyama S
    FEBS Open Bio; 2012; 2():339-44. PubMed ID: 23650612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C.
    Dethlefsen SM; Raab G; Moses MA; Adam RM; Klagsbrun M; Freeman MR
    J Cell Biochem; 1998 May; 69(2):143-53. PubMed ID: 9548562
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of membrane-bound heparin-binding epidermal growth factor-like growth factor (HB-EGF) in renal epithelial cell branching.
    Takemura T; Hino S; Okada M; Murata Y; Yanagida H; Ikeda M; Yoshioka K; Harris RC
    Kidney Int; 2002 Jun; 61(6):1968-79. PubMed ID: 12028437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of charged amino acid residues in the cytoplasmic domain of proHB-EGF.
    Nanba D; Toki F; Higashiyama S
    Biochem Biophys Res Commun; 2004 Jul; 320(2):376-82. PubMed ID: 15219838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of different ligands on epidermal growth factor receptor (EGFR) nuclear translocation.
    Faria JAQA; de Andrade C; Goes AM; Rodrigues MA; Gomes DA
    Biochem Biophys Res Commun; 2016 Sep; 478(1):39-45. PubMed ID: 27462018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ectodomain shedding of HB-EGF: a potential target for cancer therapy.
    Miyazono K
    J Biochem; 2012 Jan; 151(1):1-3. PubMed ID: 21976708
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers.
    Hirata Y; Ogasawara N; Sasaki M; Mizushima T; Shimura T; Mizoshita T; Mori Y; Kubota E; Wada T; Tanida S; Kataoka H; Kamiya T; Higashiyama S; Joh T
    Br J Cancer; 2009 Apr; 100(8):1320-9. PubMed ID: 19337254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line.
    Cheng K; Xie G; Raufman JP
    Biochem Pharmacol; 2007 Apr; 73(7):1001-12. PubMed ID: 17222808
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of the cancer cell proliferation and survival functions of proHB-EGF by using an anti-HB-EGF antibody.
    Sato S; Kamada H; Watanabe T; Tsuji I; Fan J
    PLoS One; 2013; 8(1):e54509. PubMed ID: 23349913
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.