These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 23451158)

  • 1. An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss.
    Lombino F; Biundo F; Tamayev R; Arancio O; D'Adamio L
    PLoS One; 2013; 8(2):e57120. PubMed ID: 23451158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deletion of the γ-secretase subunits Aph1B/C impairs memory and worsens the deficits of knock-in mice modeling the Alzheimer-like familial Danish dementia.
    Biundo F; Ishiwari K; Del Prete D; D'Adamio L
    Oncotarget; 2016 Mar; 7(11):11923-44. PubMed ID: 26942869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia.
    Tamayev R; D'Adamio L
    Mol Neurodegener; 2012 Apr; 7():19. PubMed ID: 22537414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia.
    Tamayev R; Matsuda S; Arancio O; D'Adamio L
    EMBO Mol Med; 2012 Mar; 4(3):171-9. PubMed ID: 22170863
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: Effects on learning and memory.
    Biundo F; Ishiwari K; Del Prete D; D'Adamio L
    Neurobiol Learn Mem; 2015 Dec; 126():18-30. PubMed ID: 26528887
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection.
    Tamayev R; Akpan N; Arancio O; Troy CM; D'Adamio L
    Mol Neurodegener; 2012 Dec; 7():60. PubMed ID: 23217200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant.
    Tamayev R; Matsuda S; Giliberto L; Arancio O; D'Adamio L
    EMBO J; 2011 May; 30(12):2501-9. PubMed ID: 21587206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased AβPP processing in familial Danish dementia patients.
    Matsuda S; Tamayev R; D'Adamio L
    J Alzheimers Dis; 2011; 27(2):385-91. PubMed ID: 21841249
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits.
    Tamayev R; Matsuda S; Fà M; Arancio O; D'Adamio L
    Proc Natl Acad Sci U S A; 2010 Nov; 107(48):20822-7. PubMed ID: 21098268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission.
    Yin T; Yao W; Norris KA; D'Adamio L
    J Biol Chem; 2021 Sep; 297(3):101089. PubMed ID: 34416235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.
    Saura CA; Chen G; Malkani S; Choi SY; Takahashi RH; Zhang D; Gouras GK; Kirkwood A; Morris RG; Shen J
    J Neurosci; 2005 Jul; 25(29):6755-64. PubMed ID: 16033885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of beta-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity.
    Ma H; Lesné S; Kotilinek L; Steidl-Nichols JV; Sherman M; Younkin L; Younkin S; Forster C; Sergeant N; Delacourte A; Vassar R; Citron M; Kofuji P; Boland LM; Ashe KH
    Proc Natl Acad Sci U S A; 2007 May; 104(19):8167-72. PubMed ID: 17470798
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Danish and British dementia ITM2b/BRI2 mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission.
    Yin T; Yao W; Lemenze AD; D'Adamio L
    J Biol Chem; 2021; 296():100054. PubMed ID: 33172889
    [TBL] [Abstract][Full Text] [Related]  

  • 14. APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions.
    Del Prete D; Lombino F; Liu X; D'Adamio L
    PLoS One; 2014; 9(9):e108576. PubMed ID: 25247712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.
    Tamayev R; Giliberto L; Li W; d'Abramo C; Arancio O; Vidal R; D'Adamio L
    J Neurosci; 2010 Nov; 30(44):14915-24. PubMed ID: 21048150
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Memory deficits of British dementia knock-in mice are prevented by Aβ-precursor protein haploinsufficiency.
    Tamayev R; D'Adamio L
    J Neurosci; 2012 Apr; 32(16):5481-5. PubMed ID: 22514310
    [TBL] [Abstract][Full Text] [Related]  

  • 17. η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
    Willem M; Tahirovic S; Busche MA; Ovsepian SV; Chafai M; Kootar S; Hornburg D; Evans LD; Moore S; Daria A; Hampel H; Müller V; Giudici C; Nuscher B; Wenninger-Weinzierl A; Kremmer E; Heneka MT; Thal DR; Giedraitis V; Lannfelt L; Müller U; Livesey FJ; Meissner F; Herms J; Konnerth A; Marie H; Haass C
    Nature; 2015 Oct; 526(7573):443-7. PubMed ID: 26322584
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
    Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
    J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease.
    Gu XH; Xu LJ; Liu ZQ; Wei B; Yang YJ; Xu GG; Yin XP; Wang W
    Behav Brain Res; 2016 Sep; 311():309-321. PubMed ID: 27233830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.