184 related articles for article (PubMed ID: 23454126)
1. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
Baird L; Dinkova-Kostova AT
Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
[TBL] [Abstract][Full Text] [Related]
2. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
Furukawa M; Xiong Y
Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
[TBL] [Abstract][Full Text] [Related]
3. Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2).
Wong DP; Wells G; Hagen T
Eur J Pharmacol; 2010 Sep; 643(2-3):188-94. PubMed ID: 20599909
[TBL] [Abstract][Full Text] [Related]
4. Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.
Eggler AL; Small E; Hannink M; Mesecar AD
Biochem J; 2009 Jul; 422(1):171-80. PubMed ID: 19489739
[TBL] [Abstract][Full Text] [Related]
5. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.
Lau A; Wang XJ; Zhao F; Villeneuve NF; Wu T; Jiang T; Sun Z; White E; Zhang DD
Mol Cell Biol; 2010 Jul; 30(13):3275-85. PubMed ID: 20421418
[TBL] [Abstract][Full Text] [Related]
6. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
[TBL] [Abstract][Full Text] [Related]
7. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
Kaspar JW; Niture SK; Jaiswal AK
J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
[TBL] [Abstract][Full Text] [Related]
8. Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex.
Baird L; Llères D; Swift S; Dinkova-Kostova AT
Proc Natl Acad Sci U S A; 2013 Sep; 110(38):15259-64. PubMed ID: 23986495
[TBL] [Abstract][Full Text] [Related]
9. Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Hubaux R; Lam WL
Biomed Res Int; 2014; 2014():159459. PubMed ID: 25114896
[TBL] [Abstract][Full Text] [Related]
10. Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.
Dinkova-Kostova AT; Kostov RV; Canning P
Arch Biochem Biophys; 2017 Mar; 617():84-93. PubMed ID: 27497696
[TBL] [Abstract][Full Text] [Related]
11. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases.
Villeneuve NF; Lau A; Zhang DD
Antioxid Redox Signal; 2010 Dec; 13(11):1699-712. PubMed ID: 20486766
[TBL] [Abstract][Full Text] [Related]
12. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
13. Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.
Iso T; Suzuki T; Baird L; Yamamoto M
Mol Cell Biol; 2016 Dec; 36(24):3100-3112. PubMed ID: 27697860
[TBL] [Abstract][Full Text] [Related]
14. Drug screening assay based on the interaction of intact Keap1 and Nrf2 proteins in cancer cells.
Zhou B; Zhang X; Wang G; Barbour KW; Berger FG; Wang Q
Bioorg Med Chem; 2019 Jan; 27(1):92-99. PubMed ID: 30473361
[TBL] [Abstract][Full Text] [Related]
15. Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.
Martinez VD; Vucic EA; Pikor LA; Thu KL; Hubaux R; Lam WL
Mol Cancer; 2013 Oct; 12(1):124. PubMed ID: 24138990
[TBL] [Abstract][Full Text] [Related]
16. Cysteine-based regulation of the CUL3 adaptor protein Keap1.
Sekhar KR; Rachakonda G; Freeman ML
Toxicol Appl Pharmacol; 2010 Apr; 244(1):21-6. PubMed ID: 19560482
[TBL] [Abstract][Full Text] [Related]
17. Monitoring Keap1-Nrf2 interactions in single live cells.
Baird L; Swift S; Llères D; Dinkova-Kostova AT
Biotechnol Adv; 2014 Nov; 32(6):1133-44. PubMed ID: 24681086
[TBL] [Abstract][Full Text] [Related]
18. Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications.
Keum YS
Ann N Y Acad Sci; 2011 Jul; 1229():184-9. PubMed ID: 21793854
[TBL] [Abstract][Full Text] [Related]
19. p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.
Tao S; Liu P; Luo G; Rojo de la Vega M; Chen H; Wu T; Tillotson J; Chapman E; Zhang DD
Mol Cell Biol; 2017 Apr; 37(8):. PubMed ID: 28115426
[TBL] [Abstract][Full Text] [Related]
20. Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes.
Ichikawa T; Li J; Meyer CJ; Janicki JS; Hannink M; Cui T
PLoS One; 2009 Dec; 4(12):e8391. PubMed ID: 20027226
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
