These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 23454131)

  • 1. Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors.
    Sánchez AI; Martínez-Barrasa V; Burgos C; Vaquero JJ; Alvarez-Builla J; Terricabras E; Segarra V
    Bioorg Med Chem; 2013 Apr; 21(8):2370-2378. PubMed ID: 23454131
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors.
    Castaño T; Wang H; Campillo NE; Ballester S; González-García C; Hernández J; Pérez C; Cuenca J; Pérez-Castillo A; Martínez A; Huertas O; Gelpí JL; Luque FJ; Ke H; Gil C
    ChemMedChem; 2009 May; 4(5):866-76. PubMed ID: 19350606
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
    Lorthiois E; Bernardelli P; Vergne F; Oliveira C; Mafroud AK; Proust E; Heuze L; Moreau F; Idrissi M; Tertre A; Bertin B; Coupe M; Wrigglesworth R; Descours A; Soulard P; Berna P
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4623-6. PubMed ID: 15324876
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, Anti-inflammatory Activity and Docking Studies of Some Newer 1,3-Thiazolidine-2,4-dione Derivatives as Dual Inhibitors of PDE4 and PDE7.
    Sharma H; Lather V; Grewal AS; Pandita D
    Curr Comput Aided Drug Des; 2019; 15(3):225-234. PubMed ID: 30280674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold.
    Sánchez AI; Meneses R; Mínguez JM; Núñez A; Castillo RR; Filace F; Burgos C; Vaquero JJ; Álvarez-Builla J; Cortés-Cabrera A; Gago F; Terricabras E; Segarra V
    Org Biomol Chem; 2014 Jun; 12(24):4233-42. PubMed ID: 24838636
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PDE7-Selective and Dual Inhibitors: Advances in Chemical and Biological Research.
    Jankowska A; Swierczek A; Chlon-Rzepa G; Pawlowski M; Wyska E
    Curr Med Chem; 2017; 24(7):673-700. PubMed ID: 28093982
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of potent pyrimidine inhibitors of phosphodiesterase 7 (PDE7) and their ability to inhibit T cell proliferation.
    Guo J; Watson A; Kempson J; Carlsen M; Barbosa J; Stebbins K; Lee D; Dodd J; Nadler SG; McKinnon M; Barrish J; Pitts WJ
    Bioorg Med Chem Lett; 2009 Apr; 19(7):1935-8. PubMed ID: 19272774
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
    Vergne F; Bernardelli P; Lorthiois E; Pham N; Proust E; Oliveira C; Mafroud AK; Royer F; Wrigglesworth R; Schellhaas J; Barvian M; Moreau F; Idrissi M; Tertre A; Bertin B; Coupe M; Berna P; Soulard P
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4607-13. PubMed ID: 15324874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
    Bernardelli P; Lorthiois E; Vergne F; Oliveira C; Mafroud AK; Proust E; Pham N; Ducrot P; Moreau F; Idrissi M; Tertre A; Bertin B; Coupe M; Chevalier E; Descours A; Berlioz-Seux F; Berna P; Li M
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4627-31. PubMed ID: 15324877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of 2-(cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as a new series of potent phosphodiesterase 7 inhibitors.
    Kawai K; Endo Y; Asano T; Amano S; Sawada K; Ueo N; Takahashi N; Sonoda Y; Nagai M; Kamei N; Nagata N
    J Med Chem; 2014 Dec; 57(23):9844-54. PubMed ID: 25383422
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors.
    García AM; Brea J; Morales-García JA; Perez DI; González A; Alonso-Gil S; Gracia-Rubio I; Ros-Simó C; Conde S; Cadavid MI; Loza MI; Perez-Castillo A; Valverde O; Martinez A; Gil C
    J Med Chem; 2014 Oct; 57(20):8590-607. PubMed ID: 25264825
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and SAR study of new phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phosphodiesterase 10A inhibitors.
    Asproni B; Murineddu G; Pau A; Pinna GA; Langgård M; Christoffersen CT; Nielsen J; Kehler J
    Bioorg Med Chem; 2011 Jan; 19(1):642-9. PubMed ID: 21087867
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and cAMP-dependent phosphodiesterase inhibition of novel thiazoloquinazoline derivatives.
    Selvam TP; Kumar PV
    Acta Pharm; 2011 Mar; 61(1):103-13. PubMed ID: 21406348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavities.
    Redondo M; Soteras I; Brea J; González-García A; Cadavid MI; Loza MI; Martinez A; Gil C; Campillo NE
    Eur J Med Chem; 2013; 70():781-8. PubMed ID: 24239625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, biological screening, and molecular docking of quinazolinone and quinazolinethione as phosphodiesterase 7 inhibitors.
    Elfeky SM; Sobahi TR; Gineinah MM; Ahmed NS
    Arch Pharm (Weinheim); 2020 Jan; 353(1):e1900211. PubMed ID: 31696968
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors.
    Kehler J; Ritzen A; Langgård M; Petersen SL; Farah MM; Bundgaard C; Christoffersen CT; Nielsen J; Kilburn JP
    Bioorg Med Chem Lett; 2011 Jun; 21(12):3738-42. PubMed ID: 21602043
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors.
    Amin KM; Hegazy GH; George RF; Ibrahim NR; Mohamed NM
    Arch Pharm (Weinheim); 2021 Sep; 354(9):e2100051. PubMed ID: 33977557
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and SAR study of 2-(4-pyridylamino)thieno[3,2-d]pyrimidin-4(3H)-ones as soluble and highly potent PDE7 inhibitors.
    Endo Y; Kawai K; Asano T; Amano S; Asanuma Y; Sawada K; Ogura K; Nagata N; Ueo N; Takahashi N; Sonoda Y; Kamei N
    Bioorg Med Chem Lett; 2015 Feb; 25(3):649-53. PubMed ID: 25529739
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new therapeutic approach in Parkinson's disease: some novel quinazoline derivatives as dual selective phosphodiesterase 1 inhibitors and anti-inflammatory agents.
    Laddha SS; Bhatnagar SP
    Bioorg Med Chem; 2009 Oct; 17(19):6796-802. PubMed ID: 19744861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation.
    Banerjee A; Yadav PS; Bajpai M; Sangana RR; Gullapalli S; Gudi GS; Gharat LA
    Bioorg Med Chem Lett; 2012 May; 22(9):3223-8. PubMed ID: 22487174
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.