327 related articles for article (PubMed ID: 23454517)
1. A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.
Lu C; Zhou Q; Yan J; Du Z; Huang L; Li X
Eur J Med Chem; 2013 Apr; 62():745-53. PubMed ID: 23454517
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Sun Y; Chen J; Chen X; Huang L; Li X
Bioorg Med Chem; 2013 Dec; 21(23):7406-17. PubMed ID: 24128814
[TBL] [Abstract][Full Text] [Related]
3. Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.
Xie SS; Wang X; Jiang N; Yu W; Wang KD; Lan JS; Li ZR; Kong LY
Eur J Med Chem; 2015 May; 95():153-65. PubMed ID: 25812965
[TBL] [Abstract][Full Text] [Related]
4. In vitro and in vivo Biological Evaluation of Newly Tacrine-Selegiline Hybrids as Multi-Target Inhibitors of Cholinesterases and Monoamine Oxidases for Alzheimer's Disease.
Huang ST; Luo JC; Zhong GH; Teng LP; Yang CY; Tang CL; Jing L; Zhou ZB; Liu J; Jiang N
Drug Des Devel Ther; 2024; 18():133-159. PubMed ID: 38283137
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
Xie SS; Wang XB; Li JY; Yang L; Kong LY
Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.
Korabecny J; Musilek K; Holas O; Binder J; Zemek F; Marek J; Pohanka M; Opletalova V; Dohnal V; Kuca K
Bioorg Med Chem Lett; 2010 Oct; 20(20):6093-5. PubMed ID: 20817518
[TBL] [Abstract][Full Text] [Related]
10. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
Samadi A; de los Ríos C; Bolea I; Chioua M; Iriepa I; Moraleda I; Bartolini M; Andrisano V; Gálvez E; Valderas C; Unzeta M; Marco-Contelles J
Eur J Med Chem; 2012 Jun; 52():251-62. PubMed ID: 22503231
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
Huang L; Su T; Shan W; Luo Z; Sun Y; He F; Li X
Bioorg Med Chem; 2012 May; 20(9):3038-48. PubMed ID: 22472046
[TBL] [Abstract][Full Text] [Related]
13. The interactions of azure B, a metabolite of methylene blue, with acetylcholinesterase and butyrylcholinesterase.
Petzer A; Harvey BH; Petzer JP
Toxicol Appl Pharmacol; 2014 Feb; 274(3):488-93. PubMed ID: 24161345
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and evaluation of novel 5,6,7-trimethoxyflavone-6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
Liao S; Deng H; Huang S; Yang J; Wang S; Yin B; Zheng T; Zhang D; Liu J; Gao G; Ma J; Deng Z
Bioorg Med Chem Lett; 2015 Apr; 25(7):1541-5. PubMed ID: 25724825
[TBL] [Abstract][Full Text] [Related]
15. New tacrine-acridine hybrids as promising multifunctional drugs for potential treatment of Alzheimer's disease.
Chufarova N; Czarnecka K; Skibiński R; Cuchra M; Majsterek I; Szymański P
Arch Pharm (Weinheim); 2018 Jul; 351(7):e1800050. PubMed ID: 29870588
[TBL] [Abstract][Full Text] [Related]
16. 4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer's Disease.
Kumar B; Dwivedi AR; Sarkar B; Gupta SK; Krishnamurthy S; Mantha AK; Parkash J; Kumar V
ACS Chem Neurosci; 2019 Jan; 10(1):252-265. PubMed ID: 30296051
[TBL] [Abstract][Full Text] [Related]
17. Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease.
Chen Y; Sun J; Peng S; Liao H; Zhang Y; Lehmann J
Arch Pharm (Weinheim); 2013 Dec; 346(12):865-71. PubMed ID: 24203864
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
[TBL] [Abstract][Full Text] [Related]
19. Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
Benek O; Soukup O; Pasdiorova M; Hroch L; Sepsova V; Jost P; Hrabinova M; Jun D; Kuca K; Zala D; Ramsay RR; Marco-Contelles J; Musilek K
ChemMedChem; 2016 Jun; 11(12):1264-9. PubMed ID: 26427608
[TBL] [Abstract][Full Text] [Related]
20. Tacrine-propargylamine derivatives with improved acetylcholinesterase inhibitory activity and lower hepatotoxicity as a potential lead compound for the treatment of Alzheimer's disease.
Mao F; Li J; Wei H; Huang L; Li X
J Enzyme Inhib Med Chem; 2015 Dec; 30(6):995-1001. PubMed ID: 25792506
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]