These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 23455440)

  • 21. Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.
    Murphy KP; Carter RJ; Lione LA; Mangiarini L; Mahal A; Bates GP; Dunnett SB; Morton AJ
    J Neurosci; 2000 Jul; 20(13):5115-23. PubMed ID: 10864968
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington's disease mice.
    Kedaigle AJ; Reidling JC; Lim RG; Adam M; Wu J; Wassie B; Stocksdale JT; Casale MS; Fraenkel E; Thompson LM
    Hum Mol Genet; 2020 Jan; 29(2):202-215. PubMed ID: 31696228
    [TBL] [Abstract][Full Text] [Related]  

  • 23. In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons.
    Thomas EA; Coppola G; Tang B; Kuhn A; Kim S; Geschwind DH; Brown TB; Luthi-Carter R; Ehrlich ME
    Hum Mol Genet; 2011 Mar; 20(6):1049-60. PubMed ID: 21177255
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
    Liu W; Chaurette J; Pfister EL; Kennington LA; Chase KO; Bullock J; Vonsattel JP; Faull RL; Macdonald D; DiFiglia M; Zamore PD; Aronin N
    J Huntingtons Dis; 2013; 2(4):491-500. PubMed ID: 25062733
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.
    Hwang YJ; Hyeon SJ; Kim Y; Lim S; Lee MY; Kim J; Londhe AM; Gotina L; Kim Y; Pae AN; Cho YS; Seong J; Seo H; Kim YK; Choo H; Ryu H; Min SJ
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):856-868. PubMed ID: 33771089
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
    Chaturvedi RK; Hennessey T; Johri A; Tiwari SK; Mishra D; Agarwal S; Kim YS; Beal MF
    Hum Mol Genet; 2012 Aug; 21(15):3474-88. PubMed ID: 22589249
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease.
    Wang F; Yang Y; Lin X; Wang JQ; Wu YS; Xie W; Wang D; Zhu S; Liao YQ; Sun Q; Yang YG; Luo HR; Guo C; Han C; Tang TS
    Hum Mol Genet; 2013 Sep; 22(18):3641-53. PubMed ID: 23669348
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease.
    Desplats PA; Lambert JR; Thomas EA
    Neurobiol Dis; 2008 Sep; 31(3):298-308. PubMed ID: 18595722
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Modulation of nucleosome dynamics in Huntington's disease.
    Stack EC; Del Signore SJ; Luthi-Carter R; Soh BY; Goldstein DR; Matson S; Goodrich S; Markey AL; Cormier K; Hagerty SW; Smith K; Ryu H; Ferrante RJ
    Hum Mol Genet; 2007 May; 16(10):1164-75. PubMed ID: 17403718
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Epigenetic and transcriptional modulation of WDR5, a chromatin remodeling protein, in Huntington's disease human induced pluripotent stem cell (hiPSC) model.
    Baronchelli S; La Spada A; Ntai A; Barbieri A; Conforti P; Jotti GS; Redaelli S; Bentivegna A; De Blasio P; Biunno I
    Mol Cell Neurosci; 2017 Jul; 82():46-57. PubMed ID: 28476540
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
    Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models.
    Horne EA; Coy J; Swinney K; Fung S; Cherry AE; Marrs WR; Naydenov AV; Lin YH; Sun X; Keene CD; Grouzmann E; Muchowski P; Bates GP; Mackie K; Stella N
    Eur J Neurosci; 2013 Feb; 37(3):429-40. PubMed ID: 23167744
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load.
    Milnerwood AJ; Raymond LA
    J Physiol; 2007 Dec; 585(Pt 3):817-31. PubMed ID: 17947312
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Micro RNA-214 contributes to proteasome independent downregulation of beta catenin in Huntington's disease knock-in striatal cell model STHdhQ111/Q111.
    Ghatak S; Raha S
    Biochem Biophys Res Commun; 2015 Apr; 459(3):509-14. PubMed ID: 25747711
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
    Cui L; Jeong H; Borovecki F; Parkhurst CN; Tanese N; Krainc D
    Cell; 2006 Oct; 127(1):59-69. PubMed ID: 17018277
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease.
    Quintanilla RA; Johnson GV
    Brain Res Bull; 2009 Oct; 80(4-5):242-7. PubMed ID: 19622387
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.
    Irmak D; Fatima A; Gutiérrez-Garcia R; Rinschen MM; Wagle P; Altmüller J; Arrigoni L; Hummel B; Klein C; Frese CK; Sawarkar R; Rada-Iglesias A; Vilchez D
    Hum Mol Genet; 2018 Dec; 27(23):4117-4134. PubMed ID: 30452683
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease.
    Milnerwood AJ; Cummings DM; Dallérac GM; Brown JY; Vatsavayai SC; Hirst MC; Rezaie P; Murphy KP
    Hum Mol Genet; 2006 May; 15(10):1690-703. PubMed ID: 16600988
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5.
    Paoletti P; Vila I; Rifé M; Lizcano JM; Alberch J; Ginés S
    J Neurosci; 2008 Oct; 28(40):10090-101. PubMed ID: 18829967
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.
    Brito V; Puigdellívol M; Giralt A; del Toro D; Alberch J; Ginés S
    Cell Death Dis; 2013 Apr; 4(4):e595. PubMed ID: 23598407
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.