BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 23455610)

  • 1. Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy.
    Schulz A; Baader SL; Niwa-Kawakita M; Jung MJ; Bauer R; Garcia C; Zoch A; Schacke S; Hagel C; Mautner VF; Hanemann CO; Dun XP; Parkinson DB; Weis J; Schröder JM; Gutmann DH; Giovannini M; Morrison H
    Nat Neurosci; 2013 Apr; 16(4):426-33. PubMed ID: 23455610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A neuronal function of the tumor suppressor protein merlin.
    Schulz A; Zoch A; Morrison H
    Acta Neuropathol Commun; 2014 Jul; 2():82. PubMed ID: 25012216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of NF2 haploinsufficiency in NF2-associated polyneuropathy.
    Hanemann CO; Diebold R; Kaufmann D
    Brain Pathol; 2007 Oct; 17(4):371-6. PubMed ID: 17655741
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling.
    Schulz A; Kyselyova A; Baader SL; Jung MJ; Zoch A; Mautner VF; Hagel C; Morrison H
    Brain; 2014 Feb; 137(Pt 2):420-32. PubMed ID: 24309211
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism.
    Wong HK; Shimizu A; Kirkpatrick ND; Garkavtsev I; Chan AW; di Tomaso E; Klagsbrun M; Jain RK
    Neoplasia; 2012 Feb; 14(2):84-94. PubMed ID: 22431917
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Missense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function.
    Yang C; Asthagiri AR; Iyer RR; Lu J; Xu DS; Ksendzovsky A; Brady RO; Zhuang Z; Lonser RR
    Proc Natl Acad Sci U S A; 2011 Mar; 108(12):4980-5. PubMed ID: 21383154
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling.
    Cui Y; Groth S; Troutman S; Carlstedt A; Sperka T; Riecken LB; Kissil JL; Jin H; Morrison H
    Oncogene; 2019 Sep; 38(36):6370-6381. PubMed ID: 31312020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis.
    Petrilli A; Bott M; Fernández-Valle C
    Oncotarget; 2013 Dec; 4(12):2354-65. PubMed ID: 24259290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
    Shimizu T; Seto A; Maita N; Hamada K; Tsukita S; Tsukita S; Hakoshima T
    J Biol Chem; 2002 Mar; 277(12):10332-6. PubMed ID: 11756419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NF2: the wizardry of merlin.
    Xiao GH; Chernoff J; Testa JR
    Genes Chromosomes Cancer; 2003 Dec; 38(4):389-99. PubMed ID: 14566860
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nf2 Mutation in Schwann Cells Delays Functional Neural Recovery Following Injury.
    Truong K; Ahmad I; Jason Clark J; Seline A; Bertroche T; Mostaert B; Van Daele DJ; Hansen MR
    Neuroscience; 2018 Mar; 374():205-213. PubMed ID: 29408605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin.
    Meng JJ; Lowrie DJ; Sun H; Dorsey E; Pelton PD; Bashour AM; Groden J; Ratner N; Ip W
    J Neurosci Res; 2000 Nov; 62(4):491-502. PubMed ID: 11070492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p21-activated kinase links Rac/Cdc42 signaling to merlin.
    Xiao GH; Beeser A; Chernoff J; Testa JR
    J Biol Chem; 2002 Jan; 277(2):883-6. PubMed ID: 11719502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, hepatocyte growth factor-regulated tyrosine kinase substrate.
    Sun CX; Haipek C; Scoles DR; Pulst SM; Giovannini M; Komada M; Gutmann DH
    Hum Mol Genet; 2002 Dec; 11(25):3167-78. PubMed ID: 12444101
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene.
    Golovnina K; Blinov A; Akhmametyeva EM; Omelyanchuk LV; Chang LS
    BMC Evol Biol; 2005 Dec; 5():69. PubMed ID: 16324214
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor.
    Hirokawa Y; Tikoo A; Huynh J; Utermark T; Hanemann CO; Giovannini M; Xiao GH; Testa JR; Wood J; Maruta H
    Cancer J; 2004; 10(1):20-6. PubMed ID: 15000491
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
    Shaw RJ; Paez JG; Curto M; Yaktine A; Pruitt WM; Saotome I; O'Bryan JP; Gupta V; Ratner N; Der CJ; Jacks T; McClatchey AI
    Dev Cell; 2001 Jul; 1(1):63-72. PubMed ID: 11703924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The neurofibromatosis type 2 gene product, merlin, reverses the F-actin cytoskeletal defects in primary human Schwannoma cells.
    Bashour AM; Meng JJ; Ip W; MacCollin M; Ratner N
    Mol Cell Biol; 2002 Feb; 22(4):1150-7. PubMed ID: 11809806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
    Hawley E; Gehlhausen J; Karchugina S; Chow HY; Araiza-Olivera D; Radu M; Smith A; Burks C; Jiang L; Li X; Bessler W; Masters A; Edwards D; Burgin C; Jones D; Yates C; Clapp DW; Chernoff J; Park SJ
    Hum Mol Genet; 2021 Aug; 30(17):1607-1617. PubMed ID: 34075397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK.
    Poulikakos PI; Xiao GH; Gallagher R; Jablonski S; Jhanwar SC; Testa JR
    Oncogene; 2006 Sep; 25(44):5960-8. PubMed ID: 16652148
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.