BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 23456977)

  • 1. Role of Bruton's tyrosine kinase in myeloma cell migration and induction of bone disease.
    Bam R; Ling W; Khan S; Pennisi A; Venkateshaiah SU; Li X; van Rhee F; Usmani S; Barlogie B; Shaughnessy J; Epstein J; Yaccoby S
    Am J Hematol; 2013 Jun; 88(6):463-71. PubMed ID: 23456977
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells.
    Bam R; Venkateshaiah SU; Khan S; Ling W; Randal SS; Li X; Zhang Q; van Rhee F; Barlogie B; Epstein J; Yaccoby S
    Blood Cancer J; 2014 Aug; 4(8):e234. PubMed ID: 25083818
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide].
    Mahajan S; Ghosh S; Sudbeck EA; Zheng Y; Downs S; Hupke M; Uckun FM
    J Biol Chem; 1999 Apr; 274(14):9587-99. PubMed ID: 10092645
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis.
    Jongstra-Bilen J; Puig Cano A; Hasija M; Xiao H; Smith CI; Cybulsky MI
    J Immunol; 2008 Jul; 181(1):288-98. PubMed ID: 18566394
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity.
    van den Akker E; van Dijk TB; Schmidt U; Felida L; Beug H; Löwenberg B; von Lindern M
    Biol Chem; 2004 May; 385(5):409-13. PubMed ID: 15196000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism.
    Uckun FM; Vassilev A; Bartell S; Zheng Y; Mahajan S; Tibbles HE
    Leuk Lymphoma; 2003 Sep; 44(9):1569-77. PubMed ID: 14565661
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro and in vivo chemosensitizing activity of LFM-A13, a dual-function inhibitor of Bruton's tyrosine kinase and polo-like kinases, against human leukemic B-cell precursors.
    Uckun F; Dibirdik I; Sarkissian A; Qazi S
    Arzneimittelforschung; 2011; 61(4):252-9. PubMed ID: 21650085
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA).
    Heinonen JE; Smith CI; Nore BF
    FEBS Lett; 2002 Sep; 527(1-3):274-8. PubMed ID: 12220673
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo pharmacokinetic features, toxicity profile, and chemosensitizing activity of alpha-cyano-beta-hydroxy-beta- methyl-N-(2,5-dibromophenyl)propenamide (LFM-A13), a novel antileukemic agent targeting Bruton's tyrosine kinase.
    Uckun FM; Zheng Y; Cetkovic-Cvrlje M; Vassilev A; Lisowski E; Waurzyniak B; Chen H; Carpenter R; Chen CL
    Clin Cancer Res; 2002 May; 8(5):1224-33. PubMed ID: 12006542
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
    Eda H; Santo L; Cirstea DD; Yee AJ; Scullen TA; Nemani N; Mishima Y; Waterman PR; Arastu-Kapur S; Evans E; Singh J; Kirk CJ; Westlin WF; Raje NS
    Leukemia; 2014 Sep; 28(9):1892-901. PubMed ID: 24518207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor.
    Gilbert C; Levasseur S; Desaulniers P; Dusseault AA; Thibault N; Bourgoin SG; Naccache PH
    J Immunol; 2003 May; 170(10):5235-43. PubMed ID: 12734372
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer.
    Tankiewicz-Kwedlo A; Hermanowicz JM; Domaniewski T; Pawlak K; Rusak M; Pryczynicz A; Surazynski A; Kaminski T; Kazberuk A; Pawlak D
    Br J Pharmacol; 2018 Mar; 175(5):743-762. PubMed ID: 29160911
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells.
    Guendel I; Iordanskiy S; Sampey GC; Van Duyne R; Calvert V; Petricoin E; Saifuddin M; Kehn-Hall K; Kashanchi F
    J Neurovirol; 2015 Jun; 21(3):257-75. PubMed ID: 25672887
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bruton's tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress.
    Ghosh S; Mohammed Z; Singh I
    J Neuroinflammation; 2021 Dec; 18(1):289. PubMed ID: 34895246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients.
    Zannettino AC; Farrugia AN; Kortesidis A; Manavis J; To LB; Martin SK; Diamond P; Tamamura H; Lapidot T; Fujii N; Gronthos S
    Cancer Res; 2005 Mar; 65(5):1700-9. PubMed ID: 15753365
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bruton's tyrosine kinase as a new therapeutic target.
    Uckun FM; Tibbles HE; Vassilev AO
    Anticancer Agents Med Chem; 2007 Nov; 7(6):624-32. PubMed ID: 18045057
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effects of Bruton tyrosine kinase inhibition on chemotaxis and superoxide generation in human neutrophils.
    Broides A; Hadad N; Levy J; Levy R
    J Clin Immunol; 2014 Jul; 34(5):555-60. PubMed ID: 24771458
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways.
    Pandey MK; Kale VP; Song C; Sung SS; Sharma AK; Talamo G; Dovat S; Amin SG
    Exp Hematol; 2014 Oct; 42(10):883-96. PubMed ID: 25034231
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.
    Tai YT; Chang BY; Kong SY; Fulciniti M; Yang G; Calle Y; Hu Y; Lin J; Zhao JJ; Cagnetta A; Cea M; Sellitto MA; Zhong MY; Wang Q; Acharya C; Carrasco DR; Buggy JJ; Elias L; Treon SP; Matsui W; Richardson P; Munshi NC; Anderson KC
    Blood; 2012 Aug; 120(9):1877-87. PubMed ID: 22689860
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Role of Bruton's tyrosine kinase in endotoxin/lipopolysaccharide-induced pyroptosis of intestinal cells in scalded mice].
    Jin X; Wan J; Duan SF; Gong YZ; Wang F; Chen XL
    Zhonghua Shao Shang Za Zhi; 2021 Jun; 37(6):546-554. PubMed ID: 34139835
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 13.