257 related articles for article (PubMed ID: 23462713)
1. Design, structure-activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi.
Keenan M; Alexander PW; Diao H; Best WM; Khong A; Kerfoot M; Thompson RC; White KL; Shackleford DM; Ryan E; Gregg AD; Charman SA; von Geldern TW; Scandale I; Chatelain E
Bioorg Med Chem; 2013 Apr; 21(7):1756-63. PubMed ID: 23462713
[TBL] [Abstract][Full Text] [Related]
2. Analogues of fenarimol are potent inhibitors of Trypanosoma cruzi and are efficacious in a murine model of Chagas disease.
Keenan M; Abbott MJ; Alexander PW; Armstrong T; Best WM; Berven B; Botero A; Chaplin JH; Charman SA; Chatelain E; von Geldern TW; Kerfoot M; Khong A; Nguyen T; McManus JD; Morizzi J; Ryan E; Scandale I; Thompson RA; Wang SZ; White KL
J Med Chem; 2012 May; 55(9):4189-204. PubMed ID: 22536986
[TBL] [Abstract][Full Text] [Related]
3. Two analogues of fenarimol show curative activity in an experimental model of Chagas disease.
Keenan M; Chaplin JH; Alexander PW; Abbott MJ; Best WM; Khong A; Botero A; Perez C; Cornwall S; Thompson RA; White KL; Shackleford DM; Koltun M; Chiu FC; Morizzi J; Ryan E; Campbell M; von Geldern TW; Scandale I; Chatelain E; Charman SA
J Med Chem; 2013 Dec; 56(24):10158-70. PubMed ID: 24304150
[TBL] [Abstract][Full Text] [Related]
4. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
de Oliveira Filho GB; Cardoso MVO; Espíndola JWP; Oliveira E Silva DA; Ferreira RS; Coelho PL; Anjos PSD; Santos ES; Meira CS; Moreira DRM; Soares MBP; Leite ACL
Eur J Med Chem; 2017 Dec; 141():346-361. PubMed ID: 29031078
[TBL] [Abstract][Full Text] [Related]
5. Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR; de Oliveira AD; Teixeira de Moraes Gomes PA; de Simone CA; Villela FS; Ferreira RS; da Silva AC; dos Santos TA; Brelaz de Castro MC; Pereira VR; Leite AC
Eur J Med Chem; 2014 Mar; 75():467-78. PubMed ID: 24561675
[TBL] [Abstract][Full Text] [Related]
6. Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo.
de Souza EM; Oliveira GM; Boykin DW; Kumar A; Hu Q; De Nazaré C Soeiro M
J Antimicrob Chemother; 2006 Sep; 58(3):610-4. PubMed ID: 16854954
[TBL] [Abstract][Full Text] [Related]
7. Discovery of Strong 3-Nitro-2-Phenyl-
Carey SM; O'Neill DM; Conner GB; Sherman J; Rodriguez A; D'Antonio EL
Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673904
[TBL] [Abstract][Full Text] [Related]
8. Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi.
Keenan M; Alexander PW; Chaplin JH; Abbott MJ; Diao H; Wang Z; Best WM; Perez CJ; Cornwall SM; Keatley SK; Thompson RC; Charman SA; White KL; Ryan E; Chen G; Ioset JR; von Geldern TW; Chatelain E
Future Med Chem; 2013 Oct; 5(15):1733-52. PubMed ID: 24144410
[TBL] [Abstract][Full Text] [Related]
9. Chagas Disease Drug Discovery: Multiparametric Lead Optimization against
Fleau C; Padilla A; Miguel-Siles J; Quesada-Campos MT; Saiz-Nicolas I; Cotillo I; Cantizani Perez J; Tarleton RL; Marco M; Courtemanche G
J Med Chem; 2019 Nov; 62(22):10362-10375. PubMed ID: 31657555
[TBL] [Abstract][Full Text] [Related]
10. The urgent need to develop new drugs and tools for the treatment of Chagas disease.
Muñoz MJ; Murcia L; Segovia M
Expert Rev Anti Infect Ther; 2011 Jan; 9(1):5-7. PubMed ID: 21171870
[No Abstract] [Full Text] [Related]
11. 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency.
Calvet CM; Vieira DF; Choi JY; Kellar D; Cameron MD; Siqueira-Neto JL; Gut J; Johnston JB; Lin L; Khan S; McKerrow JH; Roush WR; Podust LM
J Med Chem; 2014 Aug; 57(16):6989-7005. PubMed ID: 25101801
[TBL] [Abstract][Full Text] [Related]
12. Novel drug design for Chagas disease via targeting Trypanosoma cruzi tubulin: Homology modeling and binding pocket prediction on Trypanosoma cruzi tubulin polymerization inhibition by naphthoquinone derivatives.
Ogindo CO; Khraiwesh MH; George M; Brandy Y; Brandy N; Gugssa A; Ashraf M; Abbas M; Southerland WM; Lee CM; Bakare O; Fang Y
Bioorg Med Chem; 2016 Aug; 24(16):3849-55. PubMed ID: 27345756
[TBL] [Abstract][Full Text] [Related]
13. Revisiting Pyrazolo[3,4-
Bouton J; Ferreira de Almeida Fiuza L; Cardoso Santos C; Mazzarella MA; Soeiro MNC; Maes L; Karalic I; Caljon G; Van Calenbergh S
J Med Chem; 2021 Apr; 64(7):4206-4238. PubMed ID: 33784107
[TBL] [Abstract][Full Text] [Related]
14. Effects of juvenile hormone analogues (JHA) on the development of Trypanosoma cruzi.
Fichera L; Esteva M; Wimmer Z; Rodriguez JB; Gros EG
Z Naturforsch C J Biosci; 1995; 50(7-8):578-80. PubMed ID: 7546047
[TBL] [Abstract][Full Text] [Related]
15. A new chemotype with promise against Trypanosoma cruzi.
Wang X; Cal M; Kaiser M; Buckner FS; Lepesheva GI; Sanford AG; Wallick AI; Davis PH; Vennerstrom JL
Bioorg Med Chem Lett; 2020 Jan; 30(1):126778. PubMed ID: 31706668
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents.
dos Santos Filho JM; Leite AC; de Oliveira BG; Moreira DR; Lima MS; Soares MB; Leite LF
Bioorg Med Chem; 2009 Sep; 17(18):6682-91. PubMed ID: 19683450
[TBL] [Abstract][Full Text] [Related]
17. Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.
da Silva EB; Oliveira E Silva DA; Oliveira AR; da Silva Mendes CH; Dos Santos TA; da Silva AC; de Castro MC; Ferreira RS; Moreira DR; Cardoso MV; de Simone CA; Pereira VR; Leite AC
Eur J Med Chem; 2017 Apr; 130():39-50. PubMed ID: 28242550
[TBL] [Abstract][Full Text] [Related]
18. In vitro and in vivo activity of the chloroaryl-substituted imidazole viniconazole against Trypanosoma cruzi.
Silva CF; Batista Dda G; Batista MM; Lionel J; Hammer ER; Brun R; Soeiro Mde N
Parasitology; 2014 Mar; 141(3):367-73. PubMed ID: 24553079
[TBL] [Abstract][Full Text] [Related]
19. 5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: preliminary in vivo studies.
Cabrera E; Murguiondo MG; Arias MG; Arredondo C; Pintos C; Aguirre G; Fernández M; Basmadjián Y; Rosa R; Pacheco JP; Raymondo S; Di Maio R; González M; Cerecetto H
Eur J Med Chem; 2009 Oct; 44(10):3909-14. PubMed ID: 19446929
[TBL] [Abstract][Full Text] [Related]
20. Novel 2-arylazoimidazole derivatives as inhibitors of Trypanosoma cruzi proliferation: Synthesis and evaluation of their biological activity.
Salerno A; Celentano AM; López J; Lara V; Gaozza C; Balcazar DE; Carrillo C; Frank FM; Blanco MM
Eur J Med Chem; 2017 Jan; 125():327-334. PubMed ID: 27688187
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
