236 related articles for article (PubMed ID: 23469146)
1. The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.
Lin C; Lu W; Zhang W; Londoño-Joshi AI; Buchsbaum DJ; Bu G; Li Y
PLoS One; 2013; 8(2):e58102. PubMed ID: 23469146
[TBL] [Abstract][Full Text] [Related]
2. Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells.
Lu W; Liu CC; Thottassery JV; Bu G; Li Y
Biochemistry; 2010 Jun; 49(22):4635-43. PubMed ID: 20446724
[TBL] [Abstract][Full Text] [Related]
3. Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo.
Lin C; Lu W; Zhai L; Bethea T; Berry K; Qu Z; Waud WR; Li Y
FEBS Lett; 2011 Oct; 585(19):3120-5. PubMed ID: 21907199
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of LRP5/6-mediated Wnt/β-catenin signaling by Mesd attenuates hyperoxia-induced pulmonary hypertension in neonatal rats.
Alapati D; Rong M; Chen S; Lin C; Li Y; Wu S
Pediatr Res; 2013 Jun; 73(6):719-25. PubMed ID: 23481549
[TBL] [Abstract][Full Text] [Related]
5. Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.
Li Y; Chen J; Lu W; McCormick LM; Wang J; Bu G
J Cell Sci; 2005 Nov; 118(Pt 22):5305-14. PubMed ID: 16263759
[TBL] [Abstract][Full Text] [Related]
6. Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.
MacDonald BT; Semenov MV; Huang H; He X
PLoS One; 2011; 6(8):e23537. PubMed ID: 21887268
[TBL] [Abstract][Full Text] [Related]
7. β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency.
Ring L; Neth P; Weber C; Steffens S; Faussner A
Cell Signal; 2014 Feb; 26(2):260-7. PubMed ID: 24269653
[TBL] [Abstract][Full Text] [Related]
8. Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway.
Lu W; Lin C; Roberts MJ; Waud WR; Piazza GA; Li Y
PLoS One; 2011; 6(12):e29290. PubMed ID: 22195040
[TBL] [Abstract][Full Text] [Related]
9. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Fenderico N; van Scherpenzeel RC; Goldflam M; Proverbio D; Jordens I; Kralj T; Stryeck S; Bass TZ; Hermans G; Ullman C; Aastrup T; Gros P; Maurice MM
Nat Commun; 2019 Jan; 10(1):365. PubMed ID: 30664649
[TBL] [Abstract][Full Text] [Related]
10. Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta.
Moosa S; Yamamoto GL; Garbes L; Keupp K; Beleza-Meireles A; Moreno CA; Valadares ER; de Sousa SB; Maia S; Saraiva J; Honjo RS; Kim CA; Cabral de Menezes H; Lausch E; Lorini PV; Lamounier A; Carniero TCB; Giunta C; Rohrbach M; Janner M; Semler O; Beleggia F; Li Y; Yigit G; Reintjes N; Altmüller J; Nürnberg P; Cavalcanti DP; Zabel B; Warman ML; Bertola DR; Wollnik B; Netzer C
Am J Hum Genet; 2019 Oct; 105(4):836-843. PubMed ID: 31564437
[TBL] [Abstract][Full Text] [Related]
11. Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
Nagaoka T; Karasawa H; Turbyville T; Rangel MC; Castro NP; Gonzales M; Baker A; Seno M; Lockett S; Greer YE; Rubin JS; Salomon DS; Bianco C
Cell Signal; 2013 Jan; 25(1):178-89. PubMed ID: 23022962
[TBL] [Abstract][Full Text] [Related]
12. Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.
Li Y; Lu W; He X; Bu G
FEBS Lett; 2006 Oct; 580(22):5423-8. PubMed ID: 16989816
[TBL] [Abstract][Full Text] [Related]
13. Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells.
Lu W; Lin C; King TD; Chen H; Reynolds RC; Li Y
Cell Signal; 2012 Dec; 24(12):2291-6. PubMed ID: 22820499
[TBL] [Abstract][Full Text] [Related]
14. Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.
Bourhis E; Tam C; Franke Y; Bazan JF; Ernst J; Hwang J; Costa M; Cochran AG; Hannoush RN
J Biol Chem; 2010 Mar; 285(12):9172-9. PubMed ID: 20093360
[TBL] [Abstract][Full Text] [Related]
15. LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation.
Chen J; Yan H; Ren DN; Yin Y; Li Z; He Q; Wo D; Ho MS; Chen Y; Liu Z; Yang J; Liu S; Zhu W
Cell Signal; 2014 May; 26(5):1068-74. PubMed ID: 24412751
[TBL] [Abstract][Full Text] [Related]
16. Wnt co-receptor LRP5/6 overexpression confers protection against hydrogen peroxide-induced neurotoxicity and reduces tau phosphorylation in SH-SY5Y cells.
Zhang L; Bahety P; Ee PL
Neurochem Int; 2015 Aug; 87():13-21. PubMed ID: 25959626
[TBL] [Abstract][Full Text] [Related]
17. LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells.
Peröbner I; Karow M; Jochum M; Neth P
Int J Biochem Cell Biol; 2012 Nov; 44(11):1970-82. PubMed ID: 22871567
[TBL] [Abstract][Full Text] [Related]
18. Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.
Haÿ E; Buczkowski T; Marty C; Da Nascimento S; Sonnet P; Marie PJ
J Bone Miner Res; 2012 Sep; 27(9):1852-63. PubMed ID: 22576936
[TBL] [Abstract][Full Text] [Related]
19. Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains.
Liu CC; Pearson C; Bu G
J Biol Chem; 2009 May; 284(22):15299-307. PubMed ID: 19339249
[TBL] [Abstract][Full Text] [Related]
20. TRAP1 Regulates Wnt/β-Catenin Pathway through LRP5/6 Receptors Expression Modulation.
Lettini G; Condelli V; Pietrafesa M; Crispo F; Zoppoli P; Maddalena F; Laurenzana I; Sgambato A; Esposito F; Landriscina M
Int J Mol Sci; 2020 Oct; 21(20):. PubMed ID: 33065966
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
